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5-HT in migraine: evidence from 5-HT receptor antagonists for a neuronal aetiology

J.R. Fozard

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0011
Subject:
Neuroscience, Disorders of the Nervous System

The fact that antagonists at certain 5-HT receptor subtypes are effective in the prophylaxis or treatment of migraine implicates the endogenous amine in a causal role in the condition. On the basis ... More


5-HT in migraine: evidence from 5-HT1-like receptor agonists for a vascular aetiology

P.P.A. Humphrey, W. Feniuk, and M.J. Perren

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0012
Subject:
Neuroscience, Disorders of the Nervous System

Regardless of the many considerations, GR43175 has been shown to be effective when administered subcutaneously and orally as well as when administered intravenously in the treatment of acute ... More


Behavioural effects of m-chlorophenylpiperazine (m-CPP), a reported migraine precipitant

G. Curzon, G.A. Kennett, K. Shah, and P. Whitton

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0013
Subject:
Neuroscience, Disorders of the Nervous System

The anxiogenic effect may be relevant to migraine, as anxiety or stress are candidates for precipitating attacks of migraine, and it is therefore of great interest that Brewerton et al. recently ... More


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