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An Extremely Beautiful Experiment

Frederic Lawrence Holmes

in Meselson, Stahl, and the Replication of DNA: A History of "The Most Beautiful Experiment in Biology"

Published in print:
2001
Published Online:
October 2013
ISBN:
9780300085402
eISBN:
9780300129663
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300085402.003.0011
Subject:
History, History of Science, Technology, and Medicine

This chapter describes Meselson's reaction to the outcome of the transfer experiment begun in Stahl's absence. The outcome, according to Meselson, was ludicrous—an artifact due to his having mixed up ... More


One Discovery, Three Stories

Frederic Lawrence Holmes

in Meselson, Stahl, and the Replication of DNA: A History of "The Most Beautiful Experiment in Biology"

Published in print:
2001
Published Online:
October 2013
ISBN:
9780300085402
eISBN:
9780300129663
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300085402.003.0010
Subject:
History, History of Science, Technology, and Medicine

This chapter discusses Meselson's and Stahl's decision to switch from 5-BU to 15N to produce heavy DNA and, at the same time, to carry out the transfer experiments with bacteria in place of phage. ... More


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