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Bridging the Gap between Patients and Models

Ilka Diester, Franz Hefti, Isabelle Mansuy, Alvaro Pascual-Leone, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Marius Wernig, Gül Dölen, Steven E. Hyman, Lennart Mucke, Karoly Nikolich, and Bernd Sommer

in Translational Neuroscience: Toward New Therapies

Published in print:
2015
Published Online:
September 2016
ISBN:
9780262029865
eISBN:
9780262329859
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029865.003.0013
Subject:
Neuroscience, Research and Theory

Classic research into human disease tends to be top-down or bottom-up, from symptoms or genes, respectively. While bottom-up approaches may work in oncology and might advance understanding of ... More


Regional Stabilization in International Relations Theory

Norrin M. Ripsman

in Peacemaking from Above, Peace from Below: Ending Conflict between Regional Rivals

Published in print:
2016
Published Online:
January 2017
ISBN:
9781501702471
eISBN:
9781501704079
Item type:
chapter
Publisher:
Cornell University Press
DOI:
10.7591/cornell/9781501702471.003.0002
Subject:
Political Science, International Relations and Politics

This chapter presents an overview of the different possible paths to peace between regional rivals. It begins with a discussion of the complexity of regional rivalries, complicated as they are by ... More


Risk Aggregation and Capital Management

Sumit Mathur

in Investment Risk Management

Published in print:
2015
Published Online:
January 2015
ISBN:
9780199331963
eISBN:
9780190214098
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199331963.003.0014
Subject:
Economics and Finance, Financial Economics

This chapter provides an analysis of the risk aggregation process in banks in both a regulatory and a non-regulatory context. It starts with a brief introduction defining risk aggregation and ... More


The HIV Pandemic: Local and Global Implications

Eduard J. Beck, Nicholas Mays, Alan W. Whiteside, and José M. Zuniga (eds)

Published in print:
2007
Published Online:
September 2009
ISBN:
9780199237401
eISBN:
9780191723957
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199237401.001.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This book examines how local and global responses to the HIV Pandemic are shaped by the history, culture, institutions, and health system of the countries affected. Country chapters combine health ... More


Flow Protection Methods

Angela H. Arthington

in Environmental Flows: Saving Rivers in the Third Millennium

Published in print:
2012
Published Online:
May 2013
ISBN:
9780520273696
eISBN:
9780520953451
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520273696.003.0011
Subject:
Biology, Biodiversity / Conservation Biology

In the early 1990s, river scientists made the case for a broader, holistic approach to sustain and conserve river ecosystems rather than focusing on the habitat requirements of a few target species. ... More


Linking learning and consciousness: the self-organizing consciousness (SOC) model

Pierre Perruchet and Annie Vinter

in The Unity of Consciousness: Binding, Integration, and Dissociation

Published in print:
2003
Published Online:
March 2012
ISBN:
9780198508571
eISBN:
9780191687358
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198508571.003.0010
Subject:
Psychology, Cognitive Psychology

The literature on consciousness usually makes no reference to learning. Consciousness is usually construed as making accessible the end-product of the unconscious computations involved during ... More


The Israeli-Jordanian Treaty

Norrin M. Ripsman

in Peacemaking from Above, Peace from Below: Ending Conflict between Regional Rivals

Published in print:
2016
Published Online:
January 2017
ISBN:
9781501702471
eISBN:
9781501704079
Item type:
chapter
Publisher:
Cornell University Press
DOI:
10.7591/cornell/9781501702471.003.0005
Subject:
Political Science, International Relations and Politics

This chapter examines the Israeli–Jordanian peace treaty of 1994. The parties engaged in peacemaking because of statist pressures: both Israel and Jordan faced greater regional threats than their ... More


Lattice Boltzmann Models without Underlying Boolean Microdynamics

Sauro Succi

in The Lattice Boltzmann Equation: For Complex States of Flowing Matter

Published in print:
2018
Published Online:
June 2018
ISBN:
9780199592357
eISBN:
9780191847967
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199592357.003.0013
Subject:
Physics, Theoretical, Computational, and Statistical Physics, Condensed Matter Physics / Materials

Chapter 12 showed how to circumvent two major stumbling blocks of the LGCA approach: statistical noise and exponential complexity of the collision rule. Yet, the ensuing LB still remains connected to ... More


Ordering sparse matrices for band solution

I. S. Duff, A. M. Erisman, and J. K. Reid

in Direct Methods for Sparse Matrices

Published in print:
2017
Published Online:
April 2017
ISBN:
9780198508380
eISBN:
9780191746420
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198508380.003.0008
Subject:
Mathematics, Numerical Analysis

We consider a different approach to reordering to preserve sparsity, with algorithms that take a global view of the problem. We now take a top-down approach to ordering as opposed to the local ... More


Entropic Lattice Boltzmann

Sauro Succi

in The Lattice Boltzmann Equation: For Complex States of Flowing Matter

Published in print:
2018
Published Online:
June 2018
ISBN:
9780199592357
eISBN:
9780191847967
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199592357.003.0021
Subject:
Physics, Theoretical, Computational, and Statistical Physics, Condensed Matter Physics / Materials

The LB with enhanced collisions opened the way to the top-down design of LB schemes, with major gains in flexibility and computational efficiency. However, compliance with the second principle was ... More


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