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Neuroimmune Interactions That Operate In The Development And Progression Of Inflammatory Demyelinating Diseases: Lessons From Pathogenesis Of Multiple Sclerosis

Enrico Fainardi and Massimiliano Castellazzi

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0012
Subject:
Neuroscience, Molecular and Cellular Systems

Multiple sclerosis (MS) is considered an autoimmune chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal damage. The view of MS as a “two-stage ... More


Pain and the discovery of nociceptors

Perl Edward R.

in Neurobiology of Nociceptors

Published in print:
1996
Published Online:
March 2012
ISBN:
9780198523345
eISBN:
9780191724527
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523345.003.0001
Subject:
Neuroscience, Sensory and Motor Systems

Nociceptors are primary afferent neurons signalling the presence of tissue-damaging stimuli or the existence of tissue damage. Their activity produces adversive and protective reactions including the ... More


Central pain

L. S. Illis

in Spinal Cord Dysfunction: Volume II: Intervention and Treatment

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192617873
eISBN:
9780191724312
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192617873.003.0010
Subject:
Neuroscience, Disorders of the Nervous System

Central pain is the term used for pain, arising from lesions confined to the central nervous system, which is of an intense unbearable nature and often found in association with particularly ... More


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