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Thyroid Hormone Signaling as a Target of Multiple Pollutants

Barbara Demeneix

in Losing Our Minds: Effects of Chemical Pollution on the Intellectual Capacity and Mental Health of Future Generations

Published in print:
2014
Published Online:
August 2014
ISBN:
9780199917518
eISBN:
9780190232382
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199917518.003.0004
Subject:
Psychology, Behavioural Neuroendocrinology

This chapter provides a physiological framework for understanding why chemicals that interfere with thyroid hormone (TH) signaling are such a cause for concern. TH production, distribution, ... More


Control of myelin gene expression

Lynn D. Hudson, Nerissa Ko, and Jin G. Kim

in Glial Cell Development: basic principles and clinical relevance

Published in print:
1997
Published Online:
March 2012
ISBN:
9781872748542
eISBN:
9780191724367
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9781872748542.003.0006
Subject:
Neuroscience, Development

This chapter focuses on the most recent efforts on the transcription front to unravel the means by which glial cells achieve their wraps. It begins with an overview of the coordinate control of ... More


Examples of Chemical Pollution Targeting Thyroid Hormone Action

Barbara Demeneix

in Losing Our Minds: Effects of Chemical Pollution on the Intellectual Capacity and Mental Health of Future Generations

Published in print:
2014
Published Online:
August 2014
ISBN:
9780199917518
eISBN:
9780190232382
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199917518.003.0005
Subject:
Psychology, Behavioural Neuroendocrinology

Schematically, thyroid hormone (TH) structure is an iodinated pair of phenyl rings, resembling a pair of spectacles. The phenyl ring is an extremely versatile base for chemists to synthesize new ... More


Hormone regulation and the evolution of frog metamorphic diversity

Daniel R. Buchholz, Christine L. Moskalik, Saurabh S. Kulkarni, Amy R. Hollar, and Allison Ng

in Mechanisms of Life History Evolution: The Genetics and Physiology of Life History Traits and Trade-Offs

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199568765
eISBN:
9780191774591
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199568765.003.0007
Subject:
Biology, Evolutionary Biology / Genetics

A vast body of work exists on the hormonal regulation of frog metamorphosis, and a non-intersecting set of literature describes the large diversity and evolution of frog reproductive modes. Uniting ... More


Losing Our Minds: Effects of Chemical Pollution on the Intellectual Capacity and Mental Health of Future Generations

Barbara Demeneix

Published in print:
2014
Published Online:
August 2014
ISBN:
9780199917518
eISBN:
9780190232382
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199917518.001.0001
Subject:
Psychology, Behavioural Neuroendocrinology

There is a global acceleration in the incidence of neurodevelopmental disorders. Numbers of children affected by an autism spectrum disorders (ASD) in the United States has reached 1 in 88 (1 in 56 ... More


Thyroidal regulation of life history transitions in fish

Richard G. Manzon

in Mechanisms of Life History Evolution: The Genetics and Physiology of Life History Traits and Trade-Offs

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199568765
eISBN:
9780191774591
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199568765.003.0006
Subject:
Biology, Evolutionary Biology / Genetics

Among fish one can describe a wide variety of different life history transitions ranging from the transition of fry to juvenile as the yolk sac is depleted, to the dramatic ‘true’ or first ... More


Thyroid Hormone, Iodine, Selenium, and Mercury

Barbara Demeneix

in Losing Our Minds: Effects of Chemical Pollution on the Intellectual Capacity and Mental Health of Future Generations

Published in print:
2014
Published Online:
August 2014
ISBN:
9780199917518
eISBN:
9780190232382
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199917518.003.0002
Subject:
Psychology, Behavioural Neuroendocrinology

Iodine and selenium are required for the production and activation of thyroid hormone (TH). As TH is needed for brain development, iodine and selenium are required in the foetus and child and for ... More


Reactive species can be useful: Some more examples

Barry Halliwell and John M.C. Gutteridge

in Free Radicals in Biology and Medicine

Published in print:
2015
Published Online:
October 2015
ISBN:
9780198717478
eISBN:
9780191802133
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198717478.003.0008
Subject:
Biology, Biochemistry / Molecular Biology, Disease Ecology / Epidemiology

This chapter gives examples of how oxygen radicals and other reactive species (RS) are useful. It describes how enzymes such as ribonucleotide reductase (tyrosyl, glycyl, or deoxyadenosyl radicals, ... More


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