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A theoretical view of the neuron as a plastic input-output device

Ithai Rabinowitch, Michael London, and Idan Segev

in Dendrites

Published in print:
2007
Published Online:
March 2012
ISBN:
9780198566564
eISBN:
9780191724206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566564.003.0013
Subject:
Neuroscience, Molecular and Cellular Systems

Wilfrid Rall developed the theoretical foundations for understanding dendritic function almost fifty years ago. Since then his theory has been intensely employed and extended in order to explore the ... More


Synapse-to-nucleus calcium signalling

Giles E. Hardingham

in Molecular Biology of the Neuron

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198509981
eISBN:
9780191723810
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509981.003.0010
Subject:
Neuroscience, Molecular and Cellular Systems

Many extracellular stimuli result in an elevation of intracellular calcium concentration. Calcium ions act as messengers, coupling many external events or stimuli to the cell's responses to those ... More


Spine calcium signaling

Adam Carter and Bernardo Sabatini

in Dendrites

Published in print:
2007
Published Online:
March 2012
ISBN:
9780198566564
eISBN:
9780191724206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566564.003.0011
Subject:
Neuroscience, Molecular and Cellular Systems

Spines are specialized cellular compartments found at high density on the dendrites of many neurons. Glutamatergic synapses are made onto spines, which house much of the local machinery necessary to ... More


Intracellular Calcium Control Mechanisms in Glia

Maria Luisa Cotrina and Maiken Nedergaard

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0017
Subject:
Neuroscience, Development, Disorders of the Nervous System

Glial cells rely on calcium ions to display a large variety of signaling capabilities inside the cell and among neighboring cells. These calcium activities are key to regulating not only the growth ... More


A Thorny Question: The Role of Spine Morphogenesis in Adaptive Plasticity

Hamilton Andrew and Zito Karen

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0011
Subject:
Neuroscience, Research and Theory

This chapter discusses some of the most exciting recent discoveries concerning the mechanisms of spine synapse plasticity and reviews the most intriguing questions which still loom over these tiny ... More


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