Chih-Ming Ho (ed.)
- Published in print:
- 2010
- Published Online:
- September 2010
- ISBN:
- 9780199219698
- eISBN:
- 9780191594229
- Item type:
- book
- Publisher:
- Oxford University Press
- DOI:
- 10.1093/acprof:oso/9780199219698.001.0001
- Subject:
- Mathematics, Mathematical Biology
A universal goal of technological development is the enrichment of human life. The fast developments of nano/micro technologies enable us to directly handle a single cell or a single molecule. This ...
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A universal goal of technological development is the enrichment of human life. The fast developments of nano/micro technologies enable us to directly handle a single cell or a single molecule. This capability propels the molecular based diagnostic and therapeutic technologies to a new horizon. In this book, we not only examine the-state- of-art biotechnologies, but also present many cutting-edge research topics which will lead toward the next generation technologies for improving human health. With the capabilities of moving, stopping, mixing and concentrating minute amount of fluid and/or particles, microfluidic circuitry provides unprecedented functions for advancing sample preparation and cell culture processes. Integrated bio-marker sensors with microfluidics, it becomes possible to detect diseases in extremely sensitive and specific manner. With the cutting edge optical techniques and proper surface molecular modification, we can study and manipulate biological processes in live cell. While we have made significant progresses in studying and controlling the phenomena in the nano/micro scale, human health is a system issue with a length in the order of a meter. A disparity of several orders of magnitude in the length scales presents significant challenges. Our current and future tasks are to develop the seamless integration processes from materials through devices and eventually into engineering systems. Our ultimate goal is that these nano/micro technology based systems can effectively interface and direct the biological complex system toward desired fate.Less
A universal goal of technological development is the enrichment of human life. The fast developments of nano/micro technologies enable us to directly handle a single cell or a single molecule. This capability propels the molecular based diagnostic and therapeutic technologies to a new horizon. In this book, we not only examine the-state- of-art biotechnologies, but also present many cutting-edge research topics which will lead toward the next generation technologies for improving human health. With the capabilities of moving, stopping, mixing and concentrating minute amount of fluid and/or particles, microfluidic circuitry provides unprecedented functions for advancing sample preparation and cell culture processes. Integrated bio-marker sensors with microfluidics, it becomes possible to detect diseases in extremely sensitive and specific manner. With the cutting edge optical techniques and proper surface molecular modification, we can study and manipulate biological processes in live cell. While we have made significant progresses in studying and controlling the phenomena in the nano/micro scale, human health is a system issue with a length in the order of a meter. A disparity of several orders of magnitude in the length scales presents significant challenges. Our current and future tasks are to develop the seamless integration processes from materials through devices and eventually into engineering systems. Our ultimate goal is that these nano/micro technology based systems can effectively interface and direct the biological complex system toward desired fate.
Mary Jo Nye
- Published in print:
- 2011
- Published Online:
- September 2013
- ISBN:
- 9780226610634
- eISBN:
- 9780226610658
- Item type:
- chapter
- Publisher:
- University of Chicago Press
- DOI:
- 10.7208/chicago/9780226610658.003.0004
- Subject:
- History, History of Science, Technology, and Medicine
This chapter examines Michael Polanyi's work in surface chemistry and X-ray diffraction by way of analyzing how he later drew upon his experiences in order to develop the notion of the “typical” or ...
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This chapter examines Michael Polanyi's work in surface chemistry and X-ray diffraction by way of analyzing how he later drew upon his experiences in order to develop the notion of the “typical” or ordinary scientist who is at the heart of everyday scientific practice. Polanyi's investigations in these two fields generated greater skepticism and less recognition from his colleagues than his results in chemical kinetics and reaction dynamics, which are the subject of the next chapter. Polanyi's reflections on resistance to his work turned him to sociological, rather than logical, explanation, for the mechanism by which scientific priority and recognition are accorded within the structure of scientific authority. The chapter concludes with an analysis of how Polanyi reinterpreted his work on surface chemistry and X-ray diffraction within a sociological framework in two essays published in the early 1960s.Less
This chapter examines Michael Polanyi's work in surface chemistry and X-ray diffraction by way of analyzing how he later drew upon his experiences in order to develop the notion of the “typical” or ordinary scientist who is at the heart of everyday scientific practice. Polanyi's investigations in these two fields generated greater skepticism and less recognition from his colleagues than his results in chemical kinetics and reaction dynamics, which are the subject of the next chapter. Polanyi's reflections on resistance to his work turned him to sociological, rather than logical, explanation, for the mechanism by which scientific priority and recognition are accorded within the structure of scientific authority. The chapter concludes with an analysis of how Polanyi reinterpreted his work on surface chemistry and X-ray diffraction within a sociological framework in two essays published in the early 1960s.
