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Free Radicals in Biology and Medicine

Barry Halliwell and John M. C. Gutteridge

Published in print:
2015
Published Online:
October 2015
ISBN:
9780198717478
eISBN:
9780191802133
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198717478.001.0001
Subject:
Biology, Biochemistry / Molecular Biology, Disease Ecology / Epidemiology

The new edition of this well-established book is thoroughly revised and gives a comprehensive account of the role of free radicals, other reactive species (RS), and antioxidants in life, health, and ... More


Antioxidant defences synthesized in vivo

Barry Halliwell and John M.C. Gutteridge

in Free Radicals in Biology and Medicine

Published in print:
2015
Published Online:
October 2015
ISBN:
9780198717478
eISBN:
9780191802133
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198717478.003.0003
Subject:
Biology, Biochemistry / Molecular Biology, Disease Ecology / Epidemiology

This chapter defines the term ‘antioxidant’, explains the different mechanisms of antioxidant action, and describes the antioxidants synthesized by living organisms: how they are made, how they work, ... More


Reactivity of superoxide ion

Donald T. Sawyer and R. J. P. Williams

in Oxygen Chemistry

Published in print:
1992
Published Online:
November 2020
ISBN:
9780195057980
eISBN:
9780197560112
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195057980.003.0011
Subject:
Chemistry, Organic Chemistry

Reduction of dioxygen by electron transfer yields superoxide ion (O2-.), which has its negative charge and electronic spin density delocalized between the two oxygens. As such it has limited ... More


Ageing, nutrition, disease, and therapy: a role for antioxidants?

Barry Halliwell and John M.C. Gutteridge

in Free Radicals in Biology and Medicine

Published in print:
2015
Published Online:
October 2015
ISBN:
9780198717478
eISBN:
9780191802133
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198717478.003.0011
Subject:
Biology, Biochemistry / Molecular Biology, Disease Ecology / Epidemiology

This chapter reviews various theories of ageing, with a particular focus on the free-radical theory of ageing (cumulative oxidative damage by reactive species [RS] causes ageing) and the evidence ... More


Reactivity of Oxygen Radicals [HO·, RO·,·O·, HOO·, ROO·, and RC(O)O·]

Donald T. Sawyer and R. J. P. Williams

in Oxygen Chemistry

Published in print:
1992
Published Online:
November 2020
ISBN:
9780195057980
eISBN:
9780197560112
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195057980.003.0009
Subject:
Chemistry, Organic Chemistry

Oxygen radicals are defined as those molecules that contain an oxygen atom with an unpaired, nonbonding electron (e.g., HO·). Although triplet dioxygen (·O2·) and superoxide ion (O2 - ·) come under ... More


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