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Traumatic injury of spinal axons

OSAMU HONMOU and WISE YOUNG

in The Axon: Structure, Function and Pathophysiology

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.003.0025
Subject:
Neuroscience, Disorders of the Nervous System

This chapter discusses the mechanisms of axonal loss and dysfunction in spinal cord injury. It focuses on the primary causes of axonal injury, the subsequent extracellular ionic derangements that ... More


Summary of Strategies Used to Repair the Injured Spinal Cord

Gerta Vrbová and Urszula Sławin´ska

in Restorative Neurology of Spinal Cord Injury

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199746507
eISBN:
9780199918768
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199746507.003.0005
Subject:
Neuroscience, Sensory and Motor Systems, Disorders of the Nervous System

At the Summer School for Biological Treatment of Chronic Spinal Cord Injury, held in Vienna in October 2008, some approaches tested on patients, based on experimental work on animals to encourage ... More


Neural Control of Locomotion

Gerta Vrbová, Urszula Sławin´ska, and Henryk Majczyn´ski

in Restorative Neurology of Spinal Cord Injury

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199746507
eISBN:
9780199918768
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199746507.003.0004
Subject:
Neuroscience, Sensory and Motor Systems, Disorders of the Nervous System

This chapter presents animal models of spinal cord injury (SCI) and discusses how an understanding of the mechanisms responsible for producing the locomotor pattern, rhythmic limb movements ... More


Transcutaneous Lumbar Posterior Root Stimulation for Motor Control Studies and Modification of Motor Activity after Spinal Cord Injury

Karen Minassian, Ursula Hofstoetter, and Frank Rattay

in Restorative Neurology of Spinal Cord Injury

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199746507
eISBN:
9780199918768
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199746507.003.0010
Subject:
Neuroscience, Sensory and Motor Systems, Disorders of the Nervous System

A method for transcutaneous spinal cord stimulation that can be used for noninvasive investigations of lumbar neural circuits' function in human subjects was recently developed. The same technique ... More


Clinical aspects of traumatic injury to central nervous system axons

MILAN R. DIMITRIJEVIC

in The Axon: Structure, Function and Pathophysiology

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.003.0034
Subject:
Neuroscience, Disorders of the Nervous System

This chapter begins by describing the features of segmental reflex activities in patients with chronic and clinically complete spinal cord injury. It then presents evidence that some of those ... More


Human Neural Stem Cell–Mediated Repair of the Contused Spinal Cord: Timing the Microenvironment

Brian J. Cummings, Mitra J. Hooshmand, Desirée L. Salazar, and Aileen J. Anderson

in From Development to Degeneration and Regeneration of the Nervous System

Published in print:
2008
Published Online:
May 2009
ISBN:
9780195369007
eISBN:
9780199865253
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195369007.003.0015
Subject:
Neuroscience, Molecular and Cellular Systems, Development

Spinal cord injury (SCI) is a debilitating and devastating condition that affects approximately 11,000 new people in the United States each year. Understanding of the pathophysiology and potential ... More


Neurophysiological Monitoring of the Human Spinal Cord Functional Integrity during Surgical Interventions

Vedran Deletis, Francesco Sala, and Paolo Costa

in Restorative Neurology of Spinal Cord Injury

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199746507
eISBN:
9780199918768
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199746507.003.0009
Subject:
Neuroscience, Sensory and Motor Systems, Disorders of the Nervous System

This chapter describes methods used for the intraoperative neurophysiological assessment of spinal cord function, including the epidural, scalp, and electromyographic recording methods, to evaluate ... More


Therapy of acute spinal cord injury

Wise Young

in Spinal Cord Dysfunction: Volume II: Intervention and Treatment

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192617873
eISBN:
9780191724312
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192617873.003.0003
Subject:
Neuroscience, Disorders of the Nervous System

Clinical and laboratory approaches to spinal cord injury maintain the traditional pessimism first expressed in the Edwin Smith Papyrus, which regarded the possibility of recovery from spinal cord ... More


The Origin of the Interoceptive Pathway: Homeostatic Sensory Fibers and the Interoceptive Dorsal Horn

A. D. (Bud) Craig

in How Do You Feel?: An Interoceptive Moment with Your Neurobiological Self

Published in print:
2014
Published Online:
October 2017
ISBN:
9780691156767
eISBN:
9781400852727
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691156767.003.0003
Subject:
Biology, Neurobiology

This chapter describes the functional and anatomical characteristics of interoceptive processing at the levels of the primary sensory fiber and the spinal cord. The association of the spinothalamic ... More


Autonomic Regulation of the Urinary Bladder and Urethra

William C. de Groat

in Central Regulation of Autonomic Functions

Published in print:
2011
Published Online:
May 2011
ISBN:
9780195306637
eISBN:
9780199894130
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195306637.003.0019
Subject:
Neuroscience, Neuroendocrine and Autonomic

Storage and elimination of urine is dependent upon the coordinated activity of two functional units in the lower urinary tract: (1) the urinary bladder and (2) the urethra. These structures are in ... More


Restorative Neurology of Motor Control after Spinal Cord Injury: Clinical Practice

Keith Tansey, Meta M Dimitrijevic, Winfried Mayr, Manfred Bijak, and Milan R Dimitrijevic

in Restorative Neurology of Spinal Cord Injury

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199746507
eISBN:
9780199918768
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199746507.003.0003
Subject:
Neuroscience, Sensory and Motor Systems, Disorders of the Nervous System

This chapter discusses how established procedures using physiotherapy, neuromuscular and peripheral nerve stimulation, and spinal cord stimulation can be used as restorative procedures. It describes ... More


Neural Circuits: Spinal Cord, Retina, Invertebrate Systems

Gordon M. Shepherd

in Creating Modern Neuroscience: The Revolutionary 1950s

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.003.0009
Subject:
Neuroscience, History of Neuroscience

In the 1950s, the microelectrode opened the door not only to understanding the properties of the individual nerve cell, but also to how they are connected; how they “talk” to each other. Two ... More


Inductive signals and the assignment of cell fate in the spinal cord and hindbrain: An axial coordinate system for neural patterning

Thomas M. Jessell and Andrew Lumsden

in Molecular and Cellular Approaches to Neural Development

Published in print:
1998
Published Online:
May 2009
ISBN:
9780195111668
eISBN:
9780199865833
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195111668.003.0008
Subject:
Neuroscience, Molecular and Cellular Systems, Development

Recent studies of the molecular mechanisms that control the identity and pattern of neural cell types generated in vertebrate embryos have focused on three main issues: (i) defining the source and ... More


Sympathetic Preganglionic Neurons

Ida J. Llewellyn-Smith

in Central Regulation of Autonomic Functions

Published in print:
2011
Published Online:
May 2011
ISBN:
9780195306637
eISBN:
9780199894130
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195306637.003.0006
Subject:
Neuroscience, Neuroendocrine and Autonomic

Sympathetic preganglionic neurons in the lateral horn of the spinal cord are the source of sympathetic outflow to the periphery and the final site for integration of information that arises from ... More


Spinal Cord Dysfunction: Volume II: Intervention and Treatment

L. S. Illis (ed.)

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192617873
eISBN:
9780191724312
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192617873.001.0001
Subject:
Neuroscience, Disorders of the Nervous System

This is the second in a series of books dealing with the enormous clinical problem of spinal-cord dysfunction. Volume I discussed assessment; this book focuses on intervention. There are three main ... More


Restorative Neurology of Spinal Cord Injury

Milan R. Dimitrijevic, Byron A. Kakulas, W. Barry McKay, and Gerta Vrbova (eds)

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199746507
eISBN:
9780199918768
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199746507.001.0001
Subject:
Neuroscience, Sensory and Motor Systems, Disorders of the Nervous System

Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or ... More


Neurophysiological Mechanisms

Mark L. Latash

in Synergy

Published in print:
2008
Published Online:
May 2009
ISBN:
9780195333169
eISBN:
9780199864195
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195333169.003.0007
Subject:
Neuroscience, Sensory and Motor Systems, Techniques

The seventh part of this book deals with possible neurophysiological mechanisms involved in motor synergies. It starts with a discussion of the structure-function controversy in neurophysiology. ... More


Neurobiology Of Chronic Pain

Min Zhuo

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0006
Subject:
Neuroscience, Molecular and Cellular Systems

Understanding the neurobiology of sensory synapses in the central nervous system provides us with basic knowledge of physiological and pathological pain, and has the potential to reveal possible drug ... More


Brain and Spinal Cord Injury

Lorene M. Nelson, Caroline M. Tanner, Stephen K. Van Den Eeden, and Valerie M. McGuire

in Neuroepidemiology: From principles to practice

Published in print:
2004
Published Online:
September 2009
ISBN:
9780195133790
eISBN:
9780199863730
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195133790.003.10
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Up to 50% of all trauma deaths in the United States involve significant injury to the brain or spinal cord. This chapter highlights the public health significance of traumatic brain and spinal cord ... More


Epilogue

Milan R Dimitrijevic, Byron A Kakulas, W. Barry McKay, and Gerta Vrbová

in Restorative Neurology of Spinal Cord Injury

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199746507
eISBN:
9780199918768
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199746507.003.0011
Subject:
Neuroscience, Sensory and Motor Systems, Disorders of the Nervous System

This chapter evaluates the significance of considering residual neural function at the subclinical level in clinical practice to enhance the control of movement after spinal cord injury. Existing ... More


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