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Second Messenger Systems

Sean Murphy and Brian R. Pearce

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0016
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter focuses on recent developments in (predominantly astro-) glial second messenger pathways, particularly those involved in intracellular Ca2+ signaling. It illustrates signaling cascades ... More


. Second Messengers (1951–1990)

Joseph D. Robinson

in Mechanisms of Synaptic Transmission: Bridging the Gaps (1890-1990)

Published in print:
2001
Published Online:
March 2012
ISBN:
9780195137613
eISBN:
9780199848164
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195137613.003.0007
Subject:
Neuroscience, Molecular and Cellular Systems

This chapter discusses the concept of a second messenger which arose from studies on the hormonal control of glucose availability and matured into appreciations of general mechanisms for signal ... More


Metabotropic Glutamate Receptors

ROBERT BALÁZS, RICHARD J. BRIDGES, and CARL W. COTMAN

in Excitatory Amino Acid Transmission in Health and Disease

Published in print:
2005
Published Online:
January 2010
ISBN:
9780195150025
eISBN:
9780199865079
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195150025.003.0007
Subject:
Neuroscience, Sensory and Motor Systems

Metabotropic glutamate receptors (mGluRs) are a distinct family of excitatory amino acid receptors. Unlike the ionotropic glutamate receptors (iGluRs), which constitute cation-specific ion channels ... More


Metabotropic receptors mediate slow synaptic responses

Motoy Kuno

in The Synapse: Function, Plasticity, and Neurotrophism

Published in print:
1994
Published Online:
March 2012
ISBN:
9780198546870
eISBN:
9780191724350
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198546870.003.0075
Subject:
Neuroscience, Molecular and Cellular Systems

The activation of metabotropic receptors causes their target ionic channels, located at a distance, to open or close. On activation, the receptor must signal the target ionic channel via the ... More


Biochemical compartmentalization in dendrites

Fritjof Helmchen and U. Valentin Nägerl

in Dendrites

Published in print:
2016
Published Online:
May 2016
ISBN:
9780198745273
eISBN:
9780191819735
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198745273.003.0010
Subject:
Neuroscience, Sensory and Motor Systems, Molecular and Cellular Systems

Dendrites have both an electrical and a biochemical character, which are closely linked. This chapter discusses dendritic structures as compartments for chemical signals such as concentration changes ... More


Initiation of smooth muscle response

A. M. Shaw and J. C. McGrath

in The Pharmacology of Vascular Smooth Muscle

Published in print:
1996
Published Online:
March 2012
ISBN:
9780192623874
eISBN:
9780191724671
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192623874.003.0005
Subject:
Neuroscience, Sensory and Motor Systems

The tension of vascular smooth muscle is regulated by numerous exogenous chemical agents whose concentrations change in response to physiological and pathophysiological events in order to modulate ... More


Floyd E. Bloom

Larry R. Squire

in The History of Neuroscience in Autobiography: Volume 7

Published in print:
2011
Published Online:
January 2012
ISBN:
9780195396133
eISBN:
9780199918409
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195396133.003.0001
Subject:
Neuroscience, History of Neuroscience

This autobiography describes his family upbringing, his undergraduate and graduate medical education, his early clinical training and the beginnings of his neuroscience research career. The details ... More


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