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The Science of Marijuana

Leslie L. Iversen

Published in print:
2007
Published Online:
January 2010
ISBN:
9780195328240
eISBN:
9780199864751
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328240.001.0001
Subject:
Neuroscience, Sensory and Motor Systems

In this work, the author explains the remarkable advances that have been made in scientific research on cannabis with the discovery of specific receptors and the existence of naturally occurring ... More


 Storage of the Distance between Place Cell Firing Fields in the Strength of Plastic Synapses with a Novel Learning Rule

György Csizmadia and Robert U. Muller

in Hippocampal Place Fields: Relevance to Learning and Memory

Published in print:
2008
Published Online:
May 2008
ISBN:
9780195323245
eISBN:
9780199869268
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195323245.003.0025
Subject:
Psychology, Cognitive Neuroscience

The idea that the hippocampal map has the form of a Euclidean graph of the environment is far from complete. For example, it is plausible that the start of a path is signaled by place cells whose ... More


Receptor and Ion-Channel Trafficking: Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels

Stephen J. Moss and Jeremy Henley (eds)

Published in print:
2002
Published Online:
March 2012
ISBN:
9780192632241
eISBN:
9780191724763
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192632241.001.0001
Subject:
Neuroscience, Molecular and Cellular Systems

This book reviews the recent advances in understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting, and anchoring of the protein complexes making up the ... More


Shigetada Nakanishi

Larry R. Squire

in The History of Neuroscience in Autobiography Volume 6

Published in print:
2009
Published Online:
May 2009
ISBN:
9780195380101
eISBN:
9780199864362
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195380101.003.0011
Subject:
Neuroscience, History of Neuroscience

This chapter presents an autobiography of Shigetada Nakanishi. Nakanishi's early studies elucidated the characteristic precursor architectures of various neuropeptides and vasoactive peptides by ... More


Trafficking of Glutamate Receptors

ROBERT BALÁZS, RICHARD J. BRIDGES, and CARL W. COTMAN

in Excitatory Amino Acid Transmission in Health and Disease

Published in print:
2005
Published Online:
January 2010
ISBN:
9780195150025
eISBN:
9780199865079
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195150025.003.0010
Subject:
Neuroscience, Sensory and Motor Systems

The molecular composition of the excitatory synapses is far from static. Indeed, changes in the localization and density of excitatory amino acid receptors are now recognized as an essential ... More


Cortical Neurons and Their Models

Roger D. Roger and Miles A. Whittington

in Cortical Oscillations in Health and Disease

Published in print:
2010
Published Online:
May 2010
ISBN:
9780195342796
eISBN:
9780199776276
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195342796.003.0008
Subject:
Neuroscience, Molecular and Cellular Systems, Development

The complexity of behavior of single neurons derives from a number a factors: they have complicated shapes; voltage-dependent conductances have intricate properties, and the conductances are ... More


Using ancestral gene resurrection to unravel the evolution of protein function

Joseph W. Thornton and Jamie T. Bridgham

in Ancestral Sequence Reconstruction

Published in print:
2007
Published Online:
September 2008
ISBN:
9780199299188
eISBN:
9780191714979
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199299188.003.0016
Subject:
Biology, Evolutionary Biology / Genetics

This chapter reviews the use of ancestral gene resurrection to understand how the members of a biologically crucial gene family, the steroid hormone receptors, evolved their diverse and highly ... More


Neurophysiology of Hand Function

Lynette A. Jones and Susan J. Lederman

in Human Hand Function

Published in print:
2006
Published Online:
September 2007
ISBN:
9780195173154
eISBN:
9780199786749
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195173154.003.0003
Subject:
Psychology, Cognitive Neuroscience

This chapter considers human hand function from a neurophysiological perspective and begins by highlighting several areas of controversy in this research area. The structure and function of the ... More


Molecular Pharmacology of the Dopamine Receptors

Michele L. Rankin, Lisa A. Hazelwood, R. Benjamin Free, Yoon Namkung, Elizabeth B. Rex, Rebecca A. Roof, and David R. Sibley

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0006
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

Dopamine receptors are rhodopsin-like seven-transmembrane receptors (also called G protein-coupled receptors) that mediate the central and peripheral actions of dopamine. Dopamine receptors are most ... More


Markov Chain Models of Ion Channels and Calcium Release Sites

Jeffrey R. Groff, Hilary DeRemigio, and Gregory D. Smith

in Stochastic Methods in Neuroscience

Published in print:
2009
Published Online:
February 2010
ISBN:
9780199235070
eISBN:
9780191715778
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235070.003.0002
Subject:
Mathematics, Biostatistics

This chapter is an introduction to modelling stochastically gating ion channels using continuous-time discrete-state Markov chains. Analytical and numerical methods are presented for determining ... More


Molecular Organization of Glutamate Receptors in the Postsynaptic Density

ROBERT BALÁZS, RICHARD J. BRIDGES, and CARL W. COTMAN

in Excitatory Amino Acid Transmission in Health and Disease

Published in print:
2005
Published Online:
January 2010
ISBN:
9780195150025
eISBN:
9780199865079
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195150025.003.0009
Subject:
Neuroscience, Sensory and Motor Systems

A significant advance in the field of excitatory amino acid (EAA) transmission has been the great progress made toward elucidation of the molecular composition and function of the postsynaptic ... More


Signal reception: G protein-coupled receptors

Jennifer A Koenig

in Molecular Biology of the Neuron

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198509981
eISBN:
9780191723810
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509981.003.0009
Subject:
Neuroscience, Molecular and Cellular Systems

G protein-coupled receptors (GPCRs) transduce extracellular signals into a multitude of intracellular changes including changes in electrical activity, levels of second messengers, secretion, ... More


Modulation of axonal excitability by neurotransmitter receptors

JEFFERY D. KOCSIS and KAORU SAKATANI

in The Axon: Structure, Function and Pathophysiology

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.003.0014
Subject:
Neuroscience, Disorders of the Nervous System

This chapter describes axonal regions in the mammalian nervous system that have well-defined neurotransmitter receptors and discusses their possible functional significance. It focuses on the axonal ... More


Other PET Ligands Used in Epilepsy

William H. Theodore

in Neuroimaging in Epilepsy

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195342765
eISBN:
9780199863617
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195342765.003.0013
Subject:
Neuroscience, Disorders of the Nervous System

PET can be used to image neurotransmitter receptor ligands. Increased mu and delta, and probably decreased kappa opiate receptors have been demonstrated in patients with temporal lobe epilepsy (TLE). ... More


Mechanisms of Nutritional Regulation

Stephen J. Simpson and David Raubenheimer

in The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity

Published in print:
2012
Published Online:
October 2017
ISBN:
9780691145655
eISBN:
9781400842803
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691145655.003.0003
Subject:
Biology, Animal Biology

This chapter focuses on how animals are able to regulate their intake and use of multiple nutrients. To regulate the balance of nutrients eaten, an animal needs to assess the composition of available ... More


Contributions of Mesocorticolimbic Dopamine to Cognition and Executive Function

Stan B. Floresco

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0015
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

This chapter presents a summary of studies that have investigated the contribution of prefrontal cortex (PFC) dopamine (DA) transmission to higher-order cognition, and compares and contrasts the ... More


How Antipsychotics Work: Linking Receptors to Response

Nathalie Ginovart and Shitij Kapur

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0038
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

Schizophrenia is a chronic and disabling disease that typically begins during adolescence or early adult life and severely impacts psychosocial functioning. There is no known single cause of ... More


Glutamatergic Signaling In Neurogenesis

Noritaka Nakamichi and Yukio Yoneda

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0011
Subject:
Neuroscience, Molecular and Cellular Systems

This chapter summarizes recent studies on the functional expression of ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs) by neural progenitor cells isolated from ... More


Functional Neuroanatomy of Dopamine in the Striatum

Charles R. Gerfen

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0002
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

This chapter begins with a discussion of the mesostriatal dopamine system. It then covers striatal patch-matrix compartments, input—output organization of the striatal patch and matrix compartments, ... More


Functional Implications of Dopamine D2 Receptor Localization in Relation to Glutamate Neurons

Susan R. Sesack

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0003
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

This chapter focuses on dopamine (DA) receptors of the D2 class and their spatial and functional relationships with Glut neurons within the circuitry that comprises midbrain DA neurons and their ... More


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