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Detecting Positive Selection

Norman A. Johnson

in Darwinian Detectives: Revealing the Natural History of Genes and Genomes

Published in print:
2007
Published Online:
September 2007
ISBN:
9780195306750
eISBN:
9780199790203
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195306750.003.0004
Subject:
Biology, Evolutionary Biology / Genetics

Positive natural selection, though rare in comparison with negative selection, is the main evolutionary force responsible for adaptive evolutionary change. Using the neutral theory to generate null ... More


Neutral and adaptive protein evolution

ZIHENG YANG

in Computational Molecular Evolution

Published in print:
2006
Published Online:
April 2010
ISBN:
9780198567028
eISBN:
9780191728280
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198567028.003.0008
Subject:
Biology, Evolutionary Biology / Genetics

This chapter introduces the basic concepts of negative and positive selection and the major theories of molecular evolution, and reviews tests of neutrality developed in population genetics. It ... More


What Are the Genetic Differences That Made Us Human?

Norman A. Johnson

in Darwinian Detectives: Revealing the Natural History of Genes and Genomes

Published in print:
2007
Published Online:
September 2007
ISBN:
9780195306750
eISBN:
9780199790203
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195306750.003.0009
Subject:
Biology, Evolutionary Biology / Genetics

Humans differ from chimpanzees and other apes with respect to our large brains and our abilities to use language, among other differences. This chapter discusses several candidate genes involved in ... More


Natural selection and demography as causes of molecular non-randomness

Asher D. Cutter

in A Primer of Molecular Population Genetics

Published in print:
2019
Published Online:
August 2019
ISBN:
9780198838944
eISBN:
9780191874826
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198838944.003.0007
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

Chapter 7, “Natural selection and demography as causes of molecular non-randomness,” outlines the predictable molecular evolutionary patterns that arise when the Neutral Theory has its assumptions ... More


Pathophysiology of alcohol addiction

Wolfgang H. Sommer

in Alcohol: Science, Policy and Public Health

Published in print:
2013
Published Online:
May 2013
ISBN:
9780199655786
eISBN:
9780191757082
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199655786.003.0010
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter reviews major findings and concepts in the field of biological alcoholism research. It addresses four main points which aim to inform the discussion on alcohol policy and health issues ... More


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