Jump to ContentJump to Main Navigation

You are looking at 1-6 of 6 items

  • Keywords: polygenic x
Clear All Modify Search

View:

Pretend Genes

Ken Richardson

in Genes, Brains, and Human Potential: The Science and Ideology of Intelligence

Published in print:
2017
Published Online:
January 2019
ISBN:
9780231178426
eISBN:
9780231543767
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231178426.003.0002
Subject:
Psychology, Cognitive Neuroscience

Chapter 2 is about the peculiar, and largely mythical, model of the gene at the roots of the contemporary conception of intelligence, and exposes the flawed methods of inquiry (and results) developed ... More


Complex Phenotypes and the Use of Polygenic Scores to Investigate Gene × Environment Interactions for Substance Use

Michael Windle

in Statistical Approaches to Gene X Environment Interactions for Complex Phenotypes

Published in print:
2016
Published Online:
May 2017
ISBN:
9780262034685
eISBN:
9780262335522
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262034685.003.0010
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

The chapter suggests the need of a “second-generation” candidate gene approach to adapt to first-generation limitations and to strengthen efforts to study GE interactions. The sample sizes associated ... More


Genetic trait associations

Joel T. Dudley and Konrad J. Karczewski

in Exploring Personal Genomics

Published in print:
2013
Published Online:
December 2013
ISBN:
9780199644483
eISBN:
9780191774577
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199644483.003.0006
Subject:
Biology, Evolutionary Biology / Genetics

This chapter talks about the primary application of personal genomics: mainly to understand and evaluate the genetic components of personal traits, including one's risk to acquire certain various ... More


Hitchhiking and Selective Sweeps

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0008
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

When a favorable allele increases in frequency, it alters the coalescent structure (the pattern of times back to a common ancestor) at linked sites relative to that under drift. This creates patterns ... More


Changes in Genetic Variation Induced by Drift

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0011
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

In the absence of the input of new variation, drift eventually removes all of the additive-genetic variance in a population. When nonadditive genetic variance is present, some of this variation can ... More


Long-term Response: 1. Deterministic Aspects

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0025
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

In a large population in the absence of new mutation, selection is expected to eventually drive all of the additive-genetic variance in a trait toward zero, resulting in a selection limit. This ... More


View: