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Integrative Neuroscience and Personalized Medicine

Evian Gordon, MD, PhD and Stephen Koslow, PhD (eds)

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.001.0001
Subject:
Neuroscience, Disorders of the Nervous System

Key thoughts leaders and practitioners in personalized medicine distil its current status, future directions, and recommendation for successful implementation of for brain disorders. This text is a ... More


The History of Personalized Medicine

Edward Abrahams and Mike Silver

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0001
Subject:
Neuroscience, Disorders of the Nervous System

This chapter examines the historical path that has led to personalized medicine as we know it today, in the hope of gaining a better perspective on where it will take us in the not-too-distant ... More


Accelerating the Future of Personalized Medicine

Evian Gordon and Stephen H. Koslow

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0015
Subject:
Neuroscience, Disorders of the Nervous System

This chapter summarizes the key points of personalized medicine, health care, and integrative neuroscience, including actionable recommendations of how the field might best be applied so as to create ... More


Personalized Medicine and Integrative Neuroscience: Toward Consensus Markers for Disorders of Brain Health

Leanne M. Williams and Evian Gordon

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0003
Subject:
Neuroscience, Disorders of the Nervous System

In the emerging new paradigm of “Personalized Medicine,” the goal is to shift the treatment for brain-related illness from trial and error into a bull’s-eye. To date, much of the research in ... More


Personalized Medicine in Sleep Health

Ronald Grunstein

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0010
Subject:
Neuroscience, Disorders of the Nervous System

Personalized sleep medicine is an emerging area of research and practice. Sleep disorders are common with appreciable morbidity and economic impact. Recent studies have identified clear ... More


Economic Impacts of the Personalized Medicine Tsunami

Dan Segal and David E. Williams

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0014
Subject:
Neuroscience, Disorders of the Nervous System

We are in one of the most exciting periods in the evolution of health care. Never before have so many variables (that directly impact the basis of patient care) simultaneously been in transition. ... More


Personalized Medicine for Schizophrenia

Jacob S. Ballon, Ragy R. Girgis, and Jeffrey A. Lieberman

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0006
Subject:
Neuroscience, Disorders of the Nervous System

This chapter discusses the potential for personalized medicine as it applies to schizophrenia, one of the most severe mental disorders. The first half of this chapter will address the genetics of ... More


Personalized Integrative Markers for Attention Deficit/Hyperactivity Disorder in Children and Adolescents

Michael R. Kohn, Simon D. Clarke, and Leanne M. Williams

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0007
Subject:
Neuroscience, Disorders of the Nervous System

Attention Deficit Hyperactivity Disorder (ADHD) is the most common disorder of childhood-adolescent brain health. Here, we take an integrative neuroscience approach to personalized medicine. The goal ... More


An Applied Context for Personalized Medicine in Psychiatry

Alan F. Schatzberg

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0002
Subject:
Neuroscience, Disorders of the Nervous System

This chapter reviews a number of early hypotheses about the role of neurotransmitters in depression. These hypotheses had some potential, but never had the impact one might have hoped for in the ... More


A Reality Check for Personalized Medicine

Donna Dickenson

in Me Medicine vs. We Medicine: Reclaiming Biotechnology for the Common Good

Published in print:
2016
Published Online:
November 2015
ISBN:
9780231159753
eISBN:
9780231534413
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231159753.003.0001
Subject:
Public Health and Epidemiology, Public Health

This introductory chapter presents the book’s intention to give accurate, current medical and scientific evidence regarding Me mMdicine and We Medicine, as well as locating the new technologies in ... More


Measuring the Potential Health Impact of Personalized Medicine: Evidence from Multiple Sclerosis Treatments

Kristopher J. Hult

in Economic Dimensions of Personalized and Precision Medicine

Published in print:
2019
Published Online:
September 2019
ISBN:
9780226611068
eISBN:
9780226611235
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226611235.003.0008
Subject:
Economics and Finance, Microeconomics

Individuals respond to pharmaceutical treatments differently due to the heterogeneity of patient populations. This heterogeneity can make it difficult to determine how efficacious or burdensome a ... More


Setting the Stage for Personalized Medicine

Barbara Prainsack

in Personalized Medicine: Empowered Patients in the 21st Century?

Published in print:
2017
Published Online:
September 2018
ISBN:
9781479814879
eISBN:
9781479856909
Item type:
chapter
Publisher:
NYU Press
DOI:
10.18574/nyu/9781479814879.003.0001
Subject:
Sociology, Health, Illness, and Medicine

With the help of today’s technological tools medicine has become much better at measuring individual difference. Personalized medicine—especially in its iteration of Precision Medicine—seeks to ... More


The Future of Prospective Medicine Under the Food and Drug Administration Amendments Act of 2007

Barbara J. Evans

in FDA in the Twenty-First Century: The Challenges of Regulating Drugs and New Technologies

Published in print:
2015
Published Online:
May 2016
ISBN:
9780231171182
eISBN:
9780231540070
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231171182.003.0007
Subject:
Law, Medical Law

This chapter explores special challenges FDA will face when assessing the safety and effectiveness of 21st-century preventive medical products that aim to avert future disease (as opposed to treating ... More


Personalized Medicine: Empowered Patients in the 21st Century?

Barbara Prainsack

Published in print:
2017
Published Online:
September 2018
ISBN:
9781479814879
eISBN:
9781479856909
Item type:
book
Publisher:
NYU Press
DOI:
10.18574/nyu/9781479814879.001.0001
Subject:
Sociology, Health, Illness, and Medicine

Medicine has been personal since long before personalized medicine became popular as a concept. Health professionals have long taken into consideration individual characteristics of their patients ... More


Especially for you

Alan Cribb

in Healthcare in Transition: Understanding Key Ideas and Tensions in Contemporary Health Policy

Published in print:
2017
Published Online:
May 2018
ISBN:
9781447323211
eISBN:
9781447323235
Item type:
chapter
Publisher:
Policy Press
DOI:
10.1332/policypress/9781447323211.003.0005
Subject:
Social Work, Health and Mental Health

This chapter discusses one of the most important ideas shaping health-policy reform and debate: personalisation. It should be said that there is nothing new about individualising or tailoring ... More


Economic Dimensions of Personalized and Precision Medicine

Ernst R. Berndt, Dana P. Goldman, and John Rowe (eds)

Published in print:
2019
Published Online:
September 2019
ISBN:
9780226611068
eISBN:
9780226611235
Item type:
book
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226611235.001.0001
Subject:
Economics and Finance, Microeconomics

Advances in human genetics have begun to yield clinical benefits through the development of Precision Medicine (PM). The benefits of this innovation are promising, both through application of ... More


The Economic Value and Pricing of Personalized Medicine

Tomas J. Philipson

in Economic Dimensions of Personalized and Precision Medicine

Published in print:
2019
Published Online:
September 2019
ISBN:
9780226611068
eISBN:
9780226611235
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226611235.003.0002
Subject:
Economics and Finance, Microeconomics

Personalized medicine (PM) entails better tailoring therapies to patients through use of information about the patient that better predicts treatment response before undergoing treatment. We discuss ... More


Conclusion: Patient Work in the Context of Personalization

Barbara Prainsack

in Personalized Medicine: Empowered Patients in the 21st Century?

Published in print:
2017
Published Online:
September 2018
ISBN:
9781479814879
eISBN:
9781479856909
Item type:
chapter
Publisher:
NYU Press
DOI:
10.18574/nyu/9781479814879.003.0008
Subject:
Sociology, Health, Illness, and Medicine

In order to create a personalized medicine that foregrounds factors that are important to patients and enhances social solidarity we need to repoliticize understandings of patient participation and ... More


Concluding Thoughts

Miriam Solomon

in Making Medical Knowledge

Published in print:
2015
Published Online:
June 2015
ISBN:
9780198732617
eISBN:
9780191796838
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198732617.003.0010
Subject:
Philosophy, Metaphysics/Epistemology, Philosophy of Science

This chapter offers some concluding thoughts on the methods explored in this book, and on future developments. All the methods have something old and something new; something obvious and something ... More


Primary Topic Article: Genetic Research to Facilitate Personalized Medicine: Ethical and Policy Challenges

Karen J. Maschke

in The Future of Bioethics: International Dialogues

Published in print:
2014
Published Online:
January 2014
ISBN:
9780199682676
eISBN:
9780191763168
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199682676.003.0032
Subject:
Philosophy, Moral Philosophy

Several large-scale genetic research initiatives in the U.S. are specifically designed to return to participants some but not all of the genetic information obtained from analyses of their DNA. Two ... More


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