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Phase I Research and the Meaning of ‘Prospect of Direct Benefit’

Lainie Friedman Ross

in Children in Medical Research: Access versus Protection

Published in print:
2006
Published Online:
May 2006
ISBN:
9780199273287
eISBN:
9780191603655
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/0199273286.003.0007
Subject:
Philosophy, Moral Philosophy

This chapter examines the issue of whether phase I pediatric oncology trials offer the prospect of direct benefit. Phase I research is carried out to determine toxicity; the possibility of direct ... More


Medication Compliance in Pediatric Oncology

David J. Bearison and Raymond K. Mulhern

in Pediatric Psychooncology: Psychological Perspectives on Children with Cancer

Published in print:
1994
Published Online:
November 2011
ISBN:
9780195079319
eISBN:
9780199999804
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195079319.003.0005
Subject:
Palliative Care, Paediatric Palliative Medicine, Patient Care and End-of-Life Decision Making

A significant and growing problem in pediatric oncology is the alarming rates of medication noncompliance. Among adolescent oncology patients, it has been found that as many as 60 percent are not ... More


Introduction

David J. Bearison and Raymond K. Mulhern

in Pediatric Psychooncology: Psychological Perspectives on Children with Cancer

Published in print:
1994
Published Online:
November 2011
ISBN:
9780195079319
eISBN:
9780199999804
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195079319.003.0001
Subject:
Palliative Care, Paediatric Palliative Medicine, Patient Care and End-of-Life Decision Making

Cancer in children is a relatively rare disease, and yet it is the largest non-accidental cause of death of children between the ages of 2 and 16 years. In the past 30 years, the cure rate for ... More


Sibling Adaptation to the Family Crisis of Childhood Cancer

David J. Bearison and Raymond K. Mulhern

in Pediatric Psychooncology: Psychological Perspectives on Children with Cancer

Published in print:
1994
Published Online:
November 2011
ISBN:
9780195079319
eISBN:
9780199999804
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195079319.003.0007
Subject:
Palliative Care, Paediatric Palliative Medicine, Patient Care and End-of-Life Decision Making

Childhood cancer is a family crisis that poses a range of stressors and demands that affect the entire family. From a family-systems orientation, this chapter reviews studies of how siblings of ... More


Future Directions in Pediatric Psychooncology

David J. Bearison and Raymond K. Mulhern

in Pediatric Psychooncology: Psychological Perspectives on Children with Cancer

Published in print:
1994
Published Online:
November 2011
ISBN:
9780195079319
eISBN:
9780199999804
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195079319.003.0011
Subject:
Palliative Care, Paediatric Palliative Medicine, Patient Care and End-of-Life Decision Making

The primary purpose of this book is to advance the current state of knowledge in pediatric psychooncology. This chapter concludes the book by addressing future directions for research and practice in ... More


A Prospective and Retrospective View of Pediatric Hematology/Oncology

Momcilo Jankovic and Giuseppe Masera

in Comprehensive Handbook of Childhood Cancer and Sickle Cell Disease: A Biopsychosocial Approach

Published in print:
2006
Published Online:
November 2020
ISBN:
9780195169850
eISBN:
9780197562192
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195169850.003.0041
Subject:
Clinical Medicine and Allied Health, Clinical Oncology

How does one help a family whose child has been diagnosed with a life-threatening illness? It is a deceptively simple question with complicated answers. This brief chapter is not meant to be a ... More


Pediatric Psychooncology: Psychological Perspectives on Children with Cancer

David J. Bearison and Raymond K. Mulhern (eds)

Published in print:
1994
Published Online:
November 2011
ISBN:
9780195079319
eISBN:
9780199999804
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195079319.001.0001
Subject:
Palliative Care, Paediatric Palliative Medicine, Patient Care and End-of-Life Decision Making

As the practice of pediatric oncology continues to advance and prognoses continue to improve, the course of treatment for children with poor prognoses becomes more biologically aggressive, more ... More


Research Opportunities and Collaborative Multisite Studies in Psychosocial Hematology/Oncology

Stan F. Whitsett and Brad H. Pollock

in Comprehensive Handbook of Childhood Cancer and Sickle Cell Disease: A Biopsychosocial Approach

Published in print:
2006
Published Online:
November 2020
ISBN:
9780195169850
eISBN:
9780197562192
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195169850.003.0039
Subject:
Clinical Medicine and Allied Health, Clinical Oncology

Over the past several decades, dramatic improvements in outcome have occurred for children treated for cancer. Many of these advances can be attributed to the benefits of multicenter research ... More


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