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The Role of Dopamine in the Pathophysiology and Treatment of Major Depressive Disorder

Boadie W. Dunlop and Charles B. Nemeroff

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0040
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

Many of the studies exploring dopamine (DA) function in depression have produced inconsistent findings. Contributors to this inconsistency include the diagnostic heterogeneity of major depressive ... More


Dopamine Modulation of Forebrain Pathways and the Pathophysiology of Psychiatric Disorders

Anthony A. Grace

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0041
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

Dopamine (DA) has received substantial attention due to its involvement in a wide array of neurological and psychiatric disorders, ranging from Parkinson's disease to affective disorders and ... More


Disease Entities with a Temporary Autistic Phase: The Autistic Features of Rett Syndrome

Yoshiko Nomura

in The Neurology of Autism

Published in print:
2005
Published Online:
September 2007
ISBN:
9780195182224
eISBN:
9780199786701
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195182224.003.0007
Subject:
Psychology, Cognitive Neuroscience

This chapter looks at the natural course diseases that have a transient autistic phase take, using Rett syndrome (RTT) as an example. Topics discussed include the autistic features of RTT, autistic ... More


Psychiatric Epidemiology: Searching for the Causes of Mental Disorders

Ezra Susser, Sharon Schwartz, Alfredo Morabia, and Evelyn Bromet

Published in print:
2006
Published Online:
September 2009
ISBN:
9780195101812
eISBN:
9780199864096
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195101812.001.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Searching for the causes of mental disorders is as exciting as it is complex. The relationship between pathophysiology and its overt manifestations is exceedingly intricate, and often the causes of a ... More


Physiological Effects and Disease Manifestations of Performance-Enhancing Androgenic–Anabolic Steroids, Growth Hormone, and Insulin

Michael R. Graham, Julien S. Baker, Peter Evans, and Bruce Davies

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0007
Subject:
Neuroscience, Molecular and Cellular Systems

Anabolic-androgenic steroids (AASs) can be used to increase muscle mass and strength in adult males. Despite successful detection and convictions by sporting anti-doping agencies, they are still ... More


Supportive Care in Heart Failure

James Beattie and Sarah Goodlin (eds)

Published in print:
2008
Published Online:
November 2011
ISBN:
9780198570288
eISBN:
9780191730030
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198570288.001.0001
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

Heart failure occurs in almost epidemic proportions, placing a huge burden on both the healthcare system, and sufferers and their families. The care of this group of patients has evolved ... More


North America

Frank D. Ferris and Charles F. Von Gunten

in Education in Palliative Care: Building a Culture of Learning

Published in print:
2007
Published Online:
November 2011
ISBN:
9780198569855
eISBN:
9780191730443
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198569855.003.0010
Subject:
Palliative Care, Palliative Medicine Research, Patient Care and End-of-Life Decision Making

In North America, as elsewhere in the Western world, dying was a routine part of life until the mid-20th century when it became medicalized, i.e. it was primarily seen as a product of pathophysiology ... More


The Heavy Hand of the Past: Thinking About Diseases Versus Thinking About Persons

ERIC J. CASSELL

in Doctoring: The Nature of Primary Care Medicine

Published in print:
1997
Published Online:
November 2011
ISBN:
9780195113235
eISBN:
9780199999828
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195113235.003.0003
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

The problem of designing educational systems to teach methods is complicated by the fact that the kind of knowledge by which physicians know disease and the output of technology is different from and ... More


The Clinical Method

ERIC J. CASSELL

in Doctoring: The Nature of Primary Care Medicine

Published in print:
1997
Published Online:
November 2011
ISBN:
9780195113235
eISBN:
9780199999828
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195113235.003.0005
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

The clinical method is the means by which physicians discover facts about the sick or well patient and enter them into the diagnostic and therapeutic process in equal partnership with information ... More


Expectoration: pathophysiology, measurement, and therapy

Alyn H. Morice

in Supportive Care in Respiratory Disease

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199591763
eISBN:
9780191739149
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199591763.003.0016
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making

Expectoration — the removal of secretions from the chest — is a symptom which may be triggered by a wide range of respiratory conditions. Because of this diversity, an extensive armamentarium of ... More


Multidimensional assessment of dyspnea

Virginia Carrieri-Kohlman and Deborah Dudgeon

in Dyspnoea in Advanced Disease: A guide to clinical management

Published in print:
2005
Published Online:
November 2011
ISBN:
9780198530039
eISBN:
9780191730450
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198530039.003.0002
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

dyspnoea is a subjective experience that includes interactions of various physical, psychological, social, and environmental factors that influence the person's perception of the symptom. This ... More


Dyspnea in chronic obstructive pulmonary disorder

Michelle M. Peters and Denis E. Oʼdonnell

in Dyspnoea in Advanced Disease: A guide to clinical management

Published in print:
2005
Published Online:
November 2011
ISBN:
9780198530039
eISBN:
9780191730450
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198530039.003.0004
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

Respiratory discomfort or dyspnoea is the primary symptom of chronic obstructive pulmonary disorder (COPD) and is a prime contributor to the poor quality of life of patients diagnosed with this ... More


Breathlessness in advanced cancer

Deborah Dudgeon

in Dyspnoea in Advanced Disease: A guide to clinical management

Published in print:
2005
Published Online:
November 2011
ISBN:
9780198530039
eISBN:
9780191730450
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198530039.003.0005
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

Dyspnoea is a common symptom in patients with cancer, but it is often overlooked. Breathlessness can significantly increase morbidity in patients with advanced diseases. Dyspnoea is chronic with ... More


Heart Failure: Pathophysiology

Yasuhiro Ikeda, Takeshi Yamamoto, Masafumi Yano, and Masunori Matsuzaki

in Supportive Care in Heart Failure

Published in print:
2008
Published Online:
November 2011
ISBN:
9780198570288
eISBN:
9780191730030
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198570288.003.0003
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter considers the state of knowledge in the pathophysiology of heart failure (HF). In particular, it reviews the pathophysiological characteristics of HF, and describes the link between ... More


Malignant bowel obstruction

S. Lawrence Librach, A. Nina Horvath, and E. Anne Langlois

in Palliative Medicine: A case-based manual

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199694143
eISBN:
9780191739255
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199694143.003.0065
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making

This chapter explains via a case study the desired skills, attitudes, and knowledge necessary to diagnose and manage malignant bowel obstruction (MBO). It addresses several questions such as: What is ... More


Cardiac disease

Romayne Gallagher and Gil Kimel

in Palliative Medicine: A case-based manual

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199694143
eISBN:
9780191739255
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199694143.003.0095
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making

This chapter contains case studies to show the desired skills, attitudes, and knowledge required to diagnose and manage cardiac disease. It includes a variety of questions such as: How to approach ... More


Non-Pain Symptom Management

James L. Hallenbeck

in Palliative Care Perspectives

Published in print:
2003
Published Online:
November 2011
ISBN:
9780195165784
eISBN:
9780199999897
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195165784.003.0005
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter discusses the management of non-pain symptoms in terminally ill patients. These symptoms include nausea and vomiting, constipation, bowel obstruction, dyspnea, and cachexia. The chapter ... More


Cardiac Cachexia

Mitja Lainscak, Anja Sandek, and Anker D. Stefan

in Supportive Care in Heart Failure

Published in print:
2008
Published Online:
November 2011
ISBN:
9780198570288
eISBN:
9780191730030
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198570288.003.0013
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter concentrates on the pathophysiology of cardiac cachexia. It also discusses the possible clinical implications, and outlines the potential future development of therapeutic strategies. In ... More


Fatigue in Medical Illness: Research Issues

Russell K. Portenoy and Eduardo Bruera

in Issues in Palliative Care Research

Published in print:
2003
Published Online:
November 2011
ISBN:
9780195130652
eISBN:
9780199999842
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195130652.003.0010
Subject:
Palliative Care, Palliative Medicine Research, Patient Care and End-of-Life Decision Making

Fatigue is a highly prevalent and complex symptom in populations with chronic illness. Although there have been significant advances in the methodologies to measure fatigue, few scientific ... More


Contribution of experimental studies to understanding the pathophysiology of migraine

J.W. Lance, G.A. Lambert, P.J. Goadsby, and A.S. Zagami

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0003
Subject:
Neuroscience, Disorders of the Nervous System

For any hypothesis to be truly satisfying, it must be compatible with all the known facts. The manifestations of migraine are so diverse that one must resist the temptation to seize on some and ... More


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