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Redox Signaling and Vascular Function

J. Will Langston, Magdalena L. Circu, and Tak Yee Aw

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0019
Subject:
Neuroscience, Molecular and Cellular Systems

Over the last two decades, reduction-oxidation (redox) signaling has emerged as an important regulator of cell function. The growing interest in the link between redox signaling and vascular function ... More


Selective Neuronal Vulnerability in the Hippocampus: Relationship to Neurological Diseases and Mechanisms for Differential Sensitivity of Neurons to Stress

Elias K. Michaelis

in The Clinical Neurobiology of the Hippocampus: An integrative view

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199592388
eISBN:
9780199949922
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199592388.003.0004
Subject:
Neuroscience, Disorders of the Nervous System, Behavioral Neuroscience

The phenomenon of selective neuronal vulnerability to neurological diseases or insults, such as ischemia-reperfusion, brain trauma, and ageing-associated neurodegeneration, was described in the ... More


Reducing Oxidative Stress and Enhancing Neurovascular Longevity During Diabetes Mellitus

Kenneth Maiese, Zhao Zhong Chong, and Faqi Li

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0022
Subject:
Neuroscience, Molecular and Cellular Systems

This concluding chapter looks at the raves and risks of novel therapeutic strategies that are translational in nature by focusing on the complications of oxidative stress and diabetes mellitus (DM) ... More


Oxidative stress and redox regulation: adaptation, damage, repair, senescence, and death

Barry Halliwell and John M.C. Gutteridge

in Free Radicals in Biology and Medicine

Published in print:
2015
Published Online:
October 2015
ISBN:
9780198717478
eISBN:
9780191802133
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198717478.003.0005
Subject:
Biology, Biochemistry / Molecular Biology, Disease Ecology / Epidemiology

This chapter defines the terms oxidative stress and oxidative damage, and explains how they can affect cell behaviour: proliferation, adaptation, injury, senescence, intercellular communication, and ... More


Protein Misfolding, Mitochondrial Disturbances, And Kynurenines In The Pathogenesis Of Neurodegenerative Disorders

Gabriella Gárdián, Katalin Sas, József Toldi, and László Vécsei

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0018
Subject:
Neuroscience, Molecular and Cellular Systems

As a population ages, neurodegenerative diseases become increasingly prevalent. These are different clinical entities, though they display many common features in their clinical, biochemical, and ... More


Molecular stress pathways and the evolution of life histories in reptiles

Tonia S. Schwartz and Anne M. Bronikowski

in Mechanisms of Life History Evolution: The Genetics and Physiology of Life History Traits and Trade-Offs

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199568765
eISBN:
9780191774591
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199568765.003.0015
Subject:
Biology, Evolutionary Biology / Genetics

This chapter synthesizes the empirical evidence for reptiles on how environmental stresses can induce molecular stress pathways. In an evolutionary framework, it describes how these pathways can ... More


Stress responses

Nico M. van Straalen and Dick Roelofs

in An Introduction to Ecological Genomics

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199594689
eISBN:
9780191774812
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199594689.003.0201
Subject:
Biology, Ecology

This chapter discusses various signal transduction pathways involved in the stress response, including stress-activated protein kinase signalling, heat shock protein induction, oxidative stress ... More


Role of Advanced Glycation End Products, Oxidative Stress, and Inflammation in Diabetic Vascular Complications

Sho-ichi Yamagishi, Takanori Matsui, and Kazuo Nakamura

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0021
Subject:
Neuroscience, Molecular and Cellular Systems

Diabetic vascular complication is a leading cause of end-stage renal failure, acquired blindness, a variety of neuropathies, and accelerated atherosclerosis. Recent large prospective clinical studies ... More


Physiological responses of marine invertebrates to thermal stress

Nia M. Whiteley and Clara L. Mackenzie

in Stressors in the Marine Environment: Physiological and ecological responses; societal implications

Published in print:
2016
Published Online:
May 2016
ISBN:
9780198718826
eISBN:
9780191788352
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198718826.003.0004
Subject:
Biology, Aquatic Biology, Ecology

Marine invertebrates display a tremendous range of thermal sensitivities and thermal tolerance limits, but they can all experience thermal stress at their upper thermal limits. Such limits are shaped ... More


Honey bee life history plasticity: Development, behavior, and aging

Brenda Rascón, Navdeep S. Mutti, Christina Tolfsen, and Gro V. Amdam

in Mechanisms of Life History Evolution: The Genetics and Physiology of Life History Traits and Trade-Offs

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199568765
eISBN:
9780191774591
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199568765.003.0020
Subject:
Biology, Evolutionary Biology / Genetics

Honey bee (Apis mellifera) females differentiate into distinct castes during development: the primary reproductive queen and the essentially sterile worker. Workers are characterized by complex ... More


Psychosocial stress and telomere regulation

Idan Shalev and Waylon J Hastings

in Genes, brain, and emotions: Interdisciplinary and Translational Perspectives

Published in print:
2019
Published Online:
June 2019
ISBN:
9780198793014
eISBN:
9780191834745
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198793014.003.0017
Subject:
Neuroscience, Development, Disorders of the Nervous System

Telomeres, the repetitive nucleoprotein regions at chromosome ends, are hallmarks of biological aging. Deficiencies in the network of proteins and nucleic acids which govern telomere regulation ... More


The cellular responses of marine algae and invertebrates to ultraviolet radiation, alone and in combination with other common abiotic stressors

David J. Burritt and Miles D. Lamare

in Stressors in the Marine Environment: Physiological and ecological responses; societal implications

Published in print:
2016
Published Online:
May 2016
ISBN:
9780198718826
eISBN:
9780191788352
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198718826.003.0007
Subject:
Biology, Aquatic Biology, Ecology

This chapter provides an overview of the key physiological responses in marine algae and invertebrates exposed to ultraviolet radiation. It outlines the importance of spectral irradiances and ... More


Diet and Nutrition

Pamela M. Greenwood and Raja Parasuraman

in Nurturing the Older Brain and Mind

Published in print:
2012
Published Online:
August 2013
ISBN:
9780262017145
eISBN:
9780262301336
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262017145.003.0007
Subject:
Psychology, Cognitive Psychology

This chapter explores the role of diet and nutrition on cognitive aging and the cognition of animals and human beings. The association of dietary restriction with positive effects on cognition and ... More


Unraveling the Role of Mitochondria in Alzheimer’s Disease: Toward Assembling the Puzzle

Sónia C. Correia, Paula I. Moreira, and George Perry

in Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.003.0017
Subject:
Psychology, Neuropsychology

Alzheimer’s disease (AD) is an intriguing and still unsolved puzzle that has attracted, over the last decades, the interest of the scientific community. Despite the limited knowledge regarding the ... More


Urban Evolutionary Physiology

Caroline Isaksson and Frances Bonier

in Urban Evolutionary Biology

Published in print:
2020
Published Online:
June 2020
ISBN:
9780198836841
eISBN:
9780191873843
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198836841.003.0013
Subject:
Biology, Evolutionary Biology / Genetics, Biodiversity / Conservation Biology

Organisms living in urban environments are exposed to many novel, sometimes beneficial, but most often challenging conditions. These conditions include increased exposure to chemical pollution, ... More


Too Much of a Good Thing

Pete A. Ensminger

in Life Under the Sun

Published in print:
2001
Published Online:
October 2013
ISBN:
9780300088045
eISBN:
9780300133523
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300088045.003.0016
Subject:
Environmental Science, Climate

This chapter describes photosynthesis in plants as a mechanism for putting energy into food chains. This chapter also presents the impact of excess light, producing photo-oxidative stress in plants, ... More


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