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Neurotrophic factors and their receptors: Roles in neuronal development and function

Louis F. Reichardt and Fariñas Isabel

in Molecular and Cellular Approaches to Neural Development

Published in print:
1998
Published Online:
May 2009
ISBN:
9780195111668
eISBN:
9780199865833
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195111668.003.0006
Subject:
Neuroscience, Molecular and Cellular Systems, Development

Neurotrophic factors are important regulators of the development and maintenance of vertebrate nervous system. During the development of the nervous system, neuronal populations undergo a process of ... More


Growth Factors for Neurons Provided by Macroglial Cells

Bernhard Reuss and Klaus Unsicker

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0030
Subject:
Neuroscience, Development, Disorders of the Nervous System

Neuronal survival and functions require bidirectional communication between neurons and glia that involves a large variety of growth factors. Neurotrophic factors are operationally defined as ... More


Neurotrophic factors responsible for neuronal survival

Motoy Kuno

in The Synapse: Function, Plasticity, and Neurotrophism

Published in print:
1994
Published Online:
March 2012
ISBN:
9780198546870
eISBN:
9780191724350
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198546870.003.0144
Subject:
Neuroscience, Molecular and Cellular Systems

As Gutmann (1976) predicted, the analysis of neurotrophic mechanisms is easier if the nature of the trophic factor is known. Fortunately, several neurotrophic factors have been now identifed. This ... More


Mechanisms controlling the development of cortical connections at the target

David J. Price and David J. Willshaw

in Mechanisms of Cortical Development

Published in print:
2000
Published Online:
January 2010
ISBN:
9780192624277
eISBN:
9780191723735
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192624277.003.0006
Subject:
Neuroscience, Development

The preceding chapters have described how the embryonic anatomy of the early forebrain is established under the control of regulatory genes and extracellular signalling molecules. This chapter ... More


Nociceptor plasticity

S.B. Mcmahon and J.V. Priestley

in The Neurobiology of Pain: (Molecular and Cellular Neurobiology)

Published in print:
2005
Published Online:
January 2010
ISBN:
9780198515616
eISBN:
9780191723650
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198515616.003.0002
Subject:
Neuroscience, Sensory and Motor Systems

Dorsal root ganglion (DRG) neurons have traditionally been characterized based primarily on their anatomy and physiology, but in recent years neurochemical studies have revealed additional and ... More


Neurotrophic regulation at developing synapses

Motoy Kuno

in The Synapse: Function, Plasticity, and Neurotrophism

Published in print:
1994
Published Online:
March 2012
ISBN:
9780198546870
eISBN:
9780191724350
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198546870.003.0157
Subject:
Neuroscience, Molecular and Cellular Systems

The synthesis of target-derived neurotrophic factors presumably is triggered by neuron–target contacts, when the terminals of growing neurones arrive in their target field. Developmental changes at ... More


Target-dependence of the neuronal state

Motoy Kuno

in The Synapse: Function, Plasticity, and Neurotrophism

Published in print:
1994
Published Online:
March 2012
ISBN:
9780198546870
eISBN:
9780191724350
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198546870.003.0169
Subject:
Neuroscience, Molecular and Cellular Systems

The size, dendritic geometry, and electrophysiological properties of neurones are regulated by interactions with their targets. In the case of sympathetic neurones, the target-dependent alterations ... More


Neurotrophins as Regulators of Visual Cortical Plasticity

Castrén Eero and Fernando Maya Vetencourt José

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0027
Subject:
Neuroscience, Research and Theory

This chapter describes neurotrophins as regulators of visual cortical plasticity. It illustrates that brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) are popular candidate ... More


Biologics and the Human Brain

Jonathan Kimmelman

in Neuroethics in Practice

Published in print:
2013
Published Online:
May 2013
ISBN:
9780195389784
eISBN:
9780199979233
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195389784.003.0018
Subject:
Neuroscience, Behavioral Neuroscience

Biologic based approaches offer a promising set of strategies for intervening in brain function and disease. However, their development and application is beset by a series of ethical challenges. ... More


Wine Tasting, Gender, and Aging

Gordon M. Shepherd

in Neuroenology: How the Brain Creates the Taste of Wine

Published in print:
2016
Published Online:
January 2019
ISBN:
9780231177009
eISBN:
9780231542876
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231177009.003.0017
Subject:
Neuroscience, Behavioral Neuroscience

Does smell sensitivity, and by implication wine aroma sensitivity, vary with age and gender? Standardized smell tests enable these questions to be tested in large human populations. These tests show ... More


Activity-Dependent Development of Inhibitory Synapses and Innervation Pattern in the Visual Cortex: From BDNF to GABA Signaling

Josh Huang Z.

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0008
Subject:
Neuroscience, Research and Theory

This chapter hypothesizes that brain-derived neurotrophic factor (BDNF) acts as an activity-dependent retrograde signal to regulate synapse growth. The influences of altering γ-aminobutyric acid ... More


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