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Neuronal Survival is Compromised by Ethanol: Extracellular Mediators

Michael W. Miller, Maria B. Bruns, and Paula L. Hoffman

in Brain Development: Normal Processes and the Effects of Alcohol and Nicotine

Published in print:
2006
Published Online:
January 2010
ISBN:
9780195183139
eISBN:
9780199865147
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195183139.003.0015
Subject:
Neuroscience, Development

This chapter discusses the effects of ethanol on the incidence of neuronal death and the extracellular mediators that define this death. Ethanol-induced neuronal death occurs during defined periods ... More


Ageing and the death of neurones

Paul G. Shiels and R. Wayne Davies

in Molecular Biology of the Neuron

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198509981
eISBN:
9780191723810
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509981.003.0016
Subject:
Neuroscience, Molecular and Cellular Systems

The maintenance of brain function depends on the continued correct functioning of the organ's support systems (glial cells, blood supply), on maintenance of individual neurone function and ... More


Intracellular Pathways of Neuronal Death

Sandra M. Mooney and George I. Henderson

in Brain Development: Normal Processes and the Effects of Alcohol and Nicotine

Published in print:
2006
Published Online:
January 2010
ISBN:
9780195183139
eISBN:
9780199865147
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195183139.003.0006
Subject:
Neuroscience, Development

Neuronal death is essential for normal development of the central nervous system. Without it, the nervous system can become overpopulated with poorly integrated neurons and circuitry that produces ... More


Intracellular Events in Ethanol-induced Neuronal Death

Sandra M. Mooney, Michael W. Miller, and George I. Henderson

in Brain Development: Normal Processes and the Effects of Alcohol and Nicotine

Published in print:
2006
Published Online:
January 2010
ISBN:
9780195183139
eISBN:
9780199865147
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195183139.003.0016
Subject:
Neuroscience, Development

Developmental exposure to ethanol can significantly reduce the number of neurons in specific areas of the brain, resulting in a decrease in the additive processes of cell generation and migration ... More


Cytokines and neurodegeneration

Nancy Rothwell, Sarah Loddick, and Catherine Lawrence

in Immune Responses in the Nervous System

Published in print:
1997
Published Online:
March 2012
ISBN:
9781872748795
eISBN:
9780191724381
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9781872748795.003.0004
Subject:
Neuroscience, Disorders of the Nervous System

Cytokine is the term used to describe a large and expanding group or family of polypeptides which can be synthesized by most cell types, and influence numerous biological processes. Recent research ... More


Inflammatory events in focal cerebral ischaemia

Gregory J. del Zoppo and John M. Hallenbeck

in Immune and Inflammatory Responses in the Nervous System

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198509806
eISBN:
9780191724596
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509806.003.0006
Subject:
Neuroscience, Disorders of the Nervous System

This chapter examines inflammatory events associated with focal cerebral ischaemia. It evaluates the hypothesis that polymorphonuclear (PMN) leukocytes participate in microvascular responses to ... More


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