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Synapse formation: a molecular perspective

Joshua R. Sanes and Richard H. Scheller

in Molecular and Cellular Approaches to Neural Development

Published in print:
1998
Published Online:
May 2009
ISBN:
9780195111668
eISBN:
9780199865833
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195111668.003.0005
Subject:
Neuroscience, Molecular and Cellular Systems, Development

This chapter reviews recent molecular analyses of neuromuscular synaptogenesis, focusing on vertebrate synapses. It summarizes the extensive histological and electrophysiological studies have provide ... More


The role of calcium in transmitter release

Motoy Kuno

in The Synapse: Function, Plasticity, and Neurotrophism

Published in print:
1994
Published Online:
March 2012
ISBN:
9780198546870
eISBN:
9780191724350
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198546870.003.0012
Subject:
Neuroscience, Molecular and Cellular Systems

Ca2+ is an essential co-factor for transmitter release. In the absence of external Ca2+, a presynaptic impulse reaches the nerve terminal but does not release the transmitter. Intracellular ... More


Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve–muscle synapse

Sheridan L. Swope

in Receptor and Ion-Channel Trafficking: Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels

Published in print:
2002
Published Online:
March 2012
ISBN:
9780192632241
eISBN:
9780191724763
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192632241.003.0004
Subject:
Neuroscience, Molecular and Cellular Systems

Synaptic transmission is dependent on the precise juxtaposition of the presynaptic nerve terminal with a localized high density of neurotransmitter receptors in the postsynaptic cell. For decades, ... More


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