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Neurotrophic factors and their receptors: Roles in neuronal development and function

Louis F. Reichardt and Fariñas Isabel

in Molecular and Cellular Approaches to Neural Development

Published in print:
1998
Published Online:
May 2009
ISBN:
9780195111668
eISBN:
9780199865833
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195111668.003.0006
Subject:
Neuroscience, Molecular and Cellular Systems, Development

Neurotrophic factors are important regulators of the development and maintenance of vertebrate nervous system. During the development of the nervous system, neuronal populations undergo a process of ... More


Signaling Molecules: The First Growth Factor

Gordon M. Shepherd

in Creating Modern Neuroscience: The Revolutionary 1950s

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.003.0003
Subject:
Neuroscience, History of Neuroscience

This chapter details early studies on the development of nerve cells. The nervous system arises from a single fertilized egg. Classical histologists visualized this process through the cells of the ... More


Roger W. Sperry and Rita Levi-Montalcini: From Neural Growth to “Split Brains”

Stanley Finger

in Minds Behind the Brain: A history of the pioneers and their discoveries

Published in print:
2005
Published Online:
January 2010
ISBN:
9780195181821
eISBN:
9780199865277
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195181821.003.0017
Subject:
Neuroscience, History of Neuroscience

Roger W. Sperry earned a reputation for his ability to design critical experiments that demanded looking at the growing and functioning nervous system in new ways. Sperry's most important discoveries ... More


Sleep Modulation of the Expression of Plasticity Markers

James M. Krueger, Ferenc Obál Jr., Joseph W. Harding, John W. Wright, and Lynn Churchill

in Sleep and Brain Plasticity

Published in print:
2003
Published Online:
September 2009
ISBN:
9780198574002
eISBN:
9780191724145
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198574002.003.0018
Subject:
Neuroscience, Behavioral Neuroscience

This chapter shows that various compounds (such as NO and various hormones, and cytokines) share three main functional features. They are released in response to neural activity; they are somnogenic; ... More


Development of the nociceptor phenotype: role of nerve growth factor

Mendell Lorne M.

in Neurobiology of Nociceptors

Published in print:
1996
Published Online:
March 2012
ISBN:
9780198523345
eISBN:
9780191724527
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523345.003.0019
Subject:
Neuroscience, Sensory and Motor Systems

The notion that specialized nociceptors exist among the afferent fibre population is a relatively recent one. Although indirect evidence for the existence of these fibres had been available for many ... More


Nerve Growth Factor and Alzheimer’s Disease: New Twists to an Old Story

Cattaneo Antonino

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0026
Subject:
Neuroscience, Research and Theory

This chapter describes the connection between the nerve growth factor (NGF) and Alzheimer’s disease (AD). It reveals that NGF can be considered as an anti-amyloidogenic factor that normally keeps the ... More


Trophic factors

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0009
Subject:
Neuroscience, Techniques

The developing nervous system produces about twice as many neurons as will survive into adulthood, and then at the end of development, around the time of birth in mammals, there is a short period ... More


Innervation: The Body’s Internet

Kenneth Douglas

in Bioprinting: To Make Ourselves Anew

Published in print:
2021
Published Online:
June 2021
ISBN:
9780190943547
eISBN:
9780197558164
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190943547.003.0006
Subject:
Biology, Biotechnology

Abstract: This chapter informs the reader of the discovery of nerve growth factor, how it plays an important role in bioprinting by directing the growth of the axons of nerve cells along specific ... More


Neurotrophins as Regulators of Visual Cortical Plasticity

Castrén Eero and Fernando Maya Vetencourt José

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0027
Subject:
Neuroscience, Research and Theory

This chapter describes neurotrophins as regulators of visual cortical plasticity. It illustrates that brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) are popular candidate ... More


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