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Cytokine and Chemokine Receptors and Signaling

Duane R. Wesemann and Etty N. Benveniste

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0011
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter discusses the activation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway and the mechanisms that are used to control the magnitude and duration ... More


Molecular Responses to Asbestos: Induction of Cell Proliferation and Apoptosis Through Modulation of Redox-Dependent Cell Signaling Pathways

Nicholas H. Heintz and Brooke T. Mossman

in Asbestos and Its Diseases

Published in print:
2008
Published Online:
September 2009
ISBN:
9780195178692
eISBN:
9780199864591
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195178692.003.0005
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter discusses how asbestos interacts with cell-signaling pathways to modulate cell functions, including induction of proliferation and cell death, either by necrosis or by apoptosis ... More


Understanding Cancer

Cathy Hughes

in Adult Nursing Practice: Using evidence in care

Published in print:
2012
Published Online:
November 2020
ISBN:
9780199697410
eISBN:
9780191918476
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199697410.003.0014
Subject:
Clinical Medicine and Allied Health, Nursing

The aim of this chapter is provide an overview of cancer, a biologically similar, but diverse, group of diseases. Understanding the disease process will ... More


Breast lump

Hugo Farne, Edward Norris-Cervetto, and James Warbrick-Smith

in Oxford Cases in Medicine and Surgery

Published in print:
2015
Published Online:
November 2020
ISBN:
9780198716228
eISBN:
9780191916809
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198716228.003.0017
Subject:
Clinical Medicine and Allied Health, Surgery

The four most common diagnoses for a breast lump are: • Benign cystic change (also known as fibrocystic change, fibroadenosis, or benign breast change) • Fibroadenoma ... More


Understanding Renal Disorders

Debra Ugboma and Helen Willis

in Adult Nursing Practice: Using evidence in care

Published in print:
2012
Published Online:
November 2020
ISBN:
9780199697410
eISBN:
9780191918476
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199697410.003.0021
Subject:
Clinical Medicine and Allied Health, Nursing

The aim of this chapter is to provide nurses with the knowledge to be able to assess, manage, and care for people with the renal disorders chronic kidney ... More


Occupational Toxicology

Sigmund F. Zakrzewski (ed.)

in Environmental Toxicology

Published in print:
2002
Published Online:
November 2020
ISBN:
9780195148114
eISBN:
9780197565629
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195148114.003.0013
Subject:
Chemistry, Environmental Chemistry

Industrial workers make up the segment of the population that is most vulnerable to chemical injury. To protect them from occupation-related harm, the American Conference of Governmental and ... More


Oxidative stress and redox regulation: adaptation, damage, repair, senescence, and death

Barry Halliwell and John M.C. Gutteridge

in Free Radicals in Biology and Medicine

Published in print:
2015
Published Online:
October 2015
ISBN:
9780198717478
eISBN:
9780191802133
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198717478.003.0005
Subject:
Biology, Biochemistry / Molecular Biology, Disease Ecology / Epidemiology

This chapter defines the terms oxidative stress and oxidative damage, and explains how they can affect cell behaviour: proliferation, adaptation, injury, senescence, intercellular communication, and ... More


Nephrology

Iqbal Khan (ed.)

in Best of Five MCQs for the MRCP Part 1 Volume 3

Published in print:
2017
Published Online:
November 2020
ISBN:
9780198747178
eISBN:
9780191916939
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198747178.003.0005
Subject:
Clinical Medicine and Allied Health, Professional Development in Medicine

Questions What is the prevalence of Alport’s syndrome? 1 in 10000 1 in 5000 1 in 2500 1 in 1000000 1 in 100000 A 62-year-old man on chronic haemodialysis for the management of end-stage renal ... More


Management of Periocular Neoplasms

Robert C. Kersten

in Surgery of the Eyelid, Lacrimal System, and Orbit

Published in print:
2011
Published Online:
November 2020
ISBN:
9780195340211
eISBN:
9780197562574
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195340211.003.0007
Subject:
Clinical Medicine and Allied Health, Ophthalmology

Epithelial malignancy of the eyelid is a common problem, representing about 14% of skin cancers in the head and neck region. The goals when treating any skin cancer are complete elimination of the ... More


The biology of postpartum psychosis: A hypothetical model

Paola Dazzan

in Perinatal Psychiatry: The legacy of Channi Kumar

Published in print:
2014
Published Online:
November 2020
ISBN:
9780199676859
eISBN:
9780191918346
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199676859.003.0026
Subject:
Clinical Medicine and Allied Health, Psychiatry

I had the pleasure of meeting Channi Kumar as a junior psychiatry trainee at the Maudsley Hospital, when I elected to work in his clinical service as part of my rotation. It is therefore for me an ... More


Breast Surgery

Richard G. Molloy, Graham J. MacKay, Campbell S. Roxburgh, and Martha M. Quinn (eds)

in SBAs and EMIs for the General Surgery FRCS

Published in print:
2018
Published Online:
November 2020
ISBN:
9780198794158
eISBN:
9780191917134
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198794158.003.0012
Subject:
Clinical Medicine and Allied Health, Professional Development in Medicine

Questions Single Best Answers A 54 year old woman attends the breast clinic. She has a lump in the left breast that has been present for several weeks. After clinical examination and mammography, ... More


Exam 6

Rebecca Hanlon, John Curtis, Hulya Wieshmann, David White, Caren Landes, and Val Gough

in Long Cases for the Final FRCR 2B

Published in print:
2011
Published Online:
November 2020
ISBN:
9780199590001
eISBN:
9780199590001
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199590001.003.0010
Subject:
Clinical Medicine and Allied Health, Professional Development in Medicine

Case 6.1 Clinical details A 70-year-old female patient with weight loss, dyspnoea, and cough. No improvement with antibiotics. No history of immune deficiency. Imaging Chest X-ray. Axial CT ... More


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