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Human Genetic Diversity: Functional Consequences for Health and Disease

Julian C. Knight

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.001.0001
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

This book describes the remarkable progress which has been made in defining the extent and nature of human genetic variation, and its many consequences for us as individuals and in understanding ... More


Epidemiology of venous thromboembolism

Aneel A. Ashrani and John A. Heit

in Venous Thromboembolism in Advanced Disease: A clinical guide

Published in print:
2008
Published Online:
November 2011
ISBN:
9780199232048
eISBN:
9780191730337
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199232048.003.0002
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter looks at the epidemiology or health-event patterns associated with venous thromboembolism (VTE). It explains that VTE, comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), ... More


Diversity and Species Extinctions

Emily W. B. Russell Southgate

in People and the Land through Time: Linking Ecology and History, Second Edition

Published in print:
2019
Published Online:
January 2020
ISBN:
9780300225808
eISBN:
9780300249590
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300225808.003.0010
Subject:
Biology, Ecology

Species extinction leads to diversity in terms of number of species worldwide. Locally, however, immigration of species may at the same time in many areas increase the number of species, that is, the ... More


Genetic trait associations

Joel T. Dudley and Konrad J. Karczewski

in Exploring Personal Genomics

Published in print:
2013
Published Online:
December 2013
ISBN:
9780199644483
eISBN:
9780191774577
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199644483.003.0006
Subject:
Biology, Evolutionary Biology / Genetics

This chapter talks about the primary application of personal genomics: mainly to understand and evaluate the genetic components of personal traits, including one's risk to acquire certain various ... More


Integrative Approaches

Helen E. Longino

in Studying Human Behavior: How Scientists Investigate Aggression and Sexuality

Published in print:
2013
Published Online:
January 2014
ISBN:
9780226492872
eISBN:
9780226921822
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226921822.003.0006
Subject:
Philosophy, Philosophy of Science

This chapter discusses integrative approaches to studying human behavior, covering methods, scope, and assumptions. These approaches take understanding the multiplicity of factors and their ... More


Disciplining Difference: A Selective Contemporary History of Cardiovascular Epidemiology

Janet K. Shim

in Heart-Sick: The Politics of Risk, Inequality, and Heart Disease

Published in print:
2014
Published Online:
March 2016
ISBN:
9780814786833
eISBN:
9781479866748
Item type:
chapter
Publisher:
NYU Press
DOI:
10.18574/nyu/9780814786833.003.0003
Subject:
Sociology, Health, Illness, and Medicine

This chapter discusses the contemporary social and historical development of cardiovascular epidemiology. Given that epidemiology is at a historic moment in its development—social and genetic ... More


Genome-wide association studies

Thomas W Mühleisen and Sven Cichon

in Genes, brain, and emotions: Interdisciplinary and Translational Perspectives

Published in print:
2019
Published Online:
June 2019
ISBN:
9780198793014
eISBN:
9780191834745
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198793014.003.0005
Subject:
Neuroscience, Development, Disorders of the Nervous System

Genome-wide association studies (GWAS) have evolved over the past ten years into a very successful tool for investigating the genetic architecture of multifactorial human traits and disorders. One ... More


Discussion and integration of key findings

Lucy Gell, Gerhard Bühringer, Robin Room, Allaman Allamani, Francisco Jose Eiroa-Orosa, Sarah Forberger, John Holmes, Anne Lingford-Hughes, Jane McLeod, Petra Meier, and Martine Stead

in What Determines Harm from Addictive Substances and Behaviours?

Published in print:
2016
Published Online:
March 2016
ISBN:
9780198746683
eISBN:
9780191808982
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198746683.003.0006
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The factors influencing transitions between stages in the development of problem substance use and gambling are diverse and operate across three levels of analysis: the social, economic, and ... More


Approaches to reducing the harm done by addictive substances and behaviours should be comprehensive and address the whole population

Peter Anderson, Fleur Braddick, Patricia Conrod, Antoni Gual, Matilda Hellman, Silvia Matrai, David Miller, David Nutt, Jürgen Rehm, Jillian Reynolds, and Tamyko Ysa

in New Governance of Addictive Substances and Behaviours

Published in print:
2017
Published Online:
March 2017
ISBN:
9780198759836
eISBN:
9780191820809
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198759836.003.0005
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Addictive substance use and behaviours have a universal harmful impact, thus are whole-society problems. The potential of public health prevention strategies may be considered across a continuum of ... More


Theories of causation

Mark Selikowitz

in Dyslexia and Other Learning Difficulties: The Facts

Published in print:
1993
Published Online:
November 2020
ISBN:
9780192622990
eISBN:
9780191918391
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780192622990.003.0008
Subject:
Education, Teaching of Specific Groups and Special Educational Needs

In the definition of specific learning difficulties in the first chapter I emphasized that the delay in learning must be ‘unexplained’. It is, therefore, explicit in the definition that the cause ... More


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