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Structural Imaging of Mild Cognitive Impairment

Clifford R. Jack

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0012
Subject:
Neuroscience, Techniques, Development

This chapter describes the concept of mild cognitive impairment (MCI), the initial construct of amnestic MCI as well as the expanded construct that includes both amnestic and nonamnestic forms. The ... More


Alzheimer’s Disease

Maija Pihlajamäki and Hilkka Soininen

in The Clinical Neurobiology of the Hippocampus: An integrative view

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199592388
eISBN:
9780199949922
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199592388.003.0012
Subject:
Neuroscience, Disorders of the Nervous System, Behavioral Neuroscience

The clinical spectrum of hippocampal dysfunction encompasses a wide range of neuropsychiatric symptoms. The present chapter aims at addressing the hippocampal involvement in the most common form of ... More


Imaging Cognitive Decline in Aging: Predicting Decline with Structural Imaging

Jeffrey Kaye

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0010
Subject:
Neuroscience, Techniques, Development

The focus of this chapter is predicting cognitive decline or dementia in normal older people using structural imaging. Key questions addressed include the following: What are the major methods, both ... More


Amyloid Imaging and (What is “Normal”?) Aging

William E. Klunk and Chester A. Mathis

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0014
Subject:
Neuroscience, Techniques, Development

One thing that has become clear from amyloid imaging studies is how early the full burden of plaques accumulate, often by the time a patient first develops symptoms. This finding brings with it the ... More


Paths to Alzheimer Prevention

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0004
Subject:
Anthropology, Social and Cultural Anthropology

This chapter looks at the adoption in the 1980s of the clinical diagnosis known as “mild cognitive impairment” (MCI). Formal recognition of MCI, the value of which continues to be debated in some ... More


The Early Detection of Alzheimer's Disease with Positron Emission Tomography

Rachel Mistur, Lisa Mosconi, Remigiusz Switalski, Susan De Santi, Yi Li, Lidia Glodzik, Miroslaw Brys, Wai Tsui, Henry Rusinek, and Mony J. de Leon

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0011
Subject:
Neuroscience, Techniques, Development

Reductions in the cerebral metabolic rate of glucose (CMRglc), a measure of neuronal function, have proven to be a promising tool in the early diagnosis of Alzheimer's disease (AD). FDG-PET imaging ... More


Control of Symptoms: Cognitive Dysfunction

Laura Goldstein

in Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement, 2nd Edn

Published in print:
2006
Published Online:
November 2011
ISBN:
9780199212934
eISBN:
9780191730368
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199212934.003.0008
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Palliative Medicine Research

This chapter looks into the nature of cognitive changes in ALS patients, the different symptoms associated with cognitive change, and the potential interventions that may slow the progression of the ... More


The Meaning of Memory Loss: Illness, Identity, and Biography

Renée L. Beard

in Living with Alzheimer's: Managing Memory Loss, Identity, and Illness

Published in print:
2016
Published Online:
January 2017
ISBN:
9781479800117
eISBN:
9781479855377
Item type:
chapter
Publisher:
NYU Press
DOI:
10.18574/nyu/9781479800117.003.0002
Subject:
Social Work, Health and Mental Health

This introductory chapter presents the topic of the book, Alzheimer’s illness narratives, and outlines the remaining chapters. While AD is currently constructed as a problem of epidemic proportion, ... More


A Bubble Off

Frederick M. Barken

in Out of Practice: Fighting for Primary Care Medicine in America

Published in print:
2011
Published Online:
August 2016
ISBN:
9780801449765
eISBN:
9780801460609
Item type:
chapter
Publisher:
Cornell University Press
DOI:
10.7591/cornell/9780801449765.003.0006
Subject:
Public Health and Epidemiology, Public Health

This chapter discusses the prospects for primary care provided to patients with mild cognitive impairment (MCI). People with MCI have more than a benign degree of forgetfulness, yet they are not ... More


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