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Structural Imaging of Mild Cognitive Impairment

Clifford R. Jack

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0012
Subject:
Neuroscience, Techniques, Development

This chapter describes the concept of mild cognitive impairment (MCI), the initial construct of amnestic MCI as well as the expanded construct that includes both amnestic and nonamnestic forms. The ... More


Alzheimer’s Disease

Maija Pihlajamäki and Hilkka Soininen

in The Clinical Neurobiology of the Hippocampus: An integrative view

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199592388
eISBN:
9780199949922
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199592388.003.0012
Subject:
Neuroscience, Disorders of the Nervous System, Behavioral Neuroscience

The clinical spectrum of hippocampal dysfunction encompasses a wide range of neuropsychiatric symptoms. The present chapter aims at addressing the hippocampal involvement in the most common form of ... More


Imaging Cognitive Decline in Aging: Predicting Decline with Structural Imaging

Jeffrey Kaye

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0010
Subject:
Neuroscience, Techniques, Development

The focus of this chapter is predicting cognitive decline or dementia in normal older people using structural imaging. Key questions addressed include the following: What are the major methods, both ... More


Amyloid Imaging and (What is “Normal”?) Aging

William E. Klunk and Chester A. Mathis

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0014
Subject:
Neuroscience, Techniques, Development

One thing that has become clear from amyloid imaging studies is how early the full burden of plaques accumulate, often by the time a patient first develops symptoms. This finding brings with it the ... More


Paths to Alzheimer Prevention

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0004
Subject:
Anthropology, Social and Cultural Anthropology

This chapter looks at the adoption in the 1980s of the clinical diagnosis known as “mild cognitive impairment” (MCI). Formal recognition of MCI, the value of which continues to be debated in some ... More


The Early Detection of Alzheimer's Disease with Positron Emission Tomography

Rachel Mistur, Lisa Mosconi, Remigiusz Switalski, Susan De Santi, Yi Li, Lidia Glodzik, Miroslaw Brys, Wai Tsui, Henry Rusinek, and Mony J. de Leon

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0011
Subject:
Neuroscience, Techniques, Development

Reductions in the cerebral metabolic rate of glucose (CMRglc), a measure of neuronal function, have proven to be a promising tool in the early diagnosis of Alzheimer's disease (AD). FDG-PET imaging ... More


Neuropsychological Contributions to the Diagnosis of Mild Cognitive Impairment Associated With Alzheimer’s Disease

Joel Eppig, Madeleine Werhane, Emily C. Edmonds, Lisa-Delano Wood, Katherine J. Bangen, Amy Jak, Kelsey R. Thomas, Christina Wong, Alexandra Weigand, and Mark W. Bondi

in Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.003.0004
Subject:
Psychology, Neuropsychology

Mild cognitive impairment (MCI) has long been conceptualized as a transitional stage between normal aging and Alzheimer’s disease (AD) and other dementia subtypes, thus providing a potential window ... More


Decline in Everyday Functioning in MCI and Dementia: A Neuropsychological Perspective

Rachel Mis and Tania Giovannetti

in Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.003.0006
Subject:
Psychology, Neuropsychology

Performance of everyday activities requires the coordination of a variety of complex cognitive processes; thus, as cognition changes over time, so too does the ability to perform everyday activities. ... More


Control of Symptoms: Cognitive Dysfunction

Laura Goldstein

in Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement, 2nd Edn

Published in print:
2006
Published Online:
November 2011
ISBN:
9780199212934
eISBN:
9780191730368
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199212934.003.0008
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Palliative Medicine Research

This chapter looks into the nature of cognitive changes in ALS patients, the different symptoms associated with cognitive change, and the potential interventions that may slow the progression of the ... More


Vascular Cognitive Impairment

Victor Wasserman, Sheina Emrani, Emily Matusz, Catherine C. Price, Melissa Lamar, Rodney A. Swenson, Kenneth M. Heilman, and David J. Libon

in Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.003.0005
Subject:
Psychology, Neuropsychology

The term vascular cognitive impairment (VCI) was introduced and designed to encompass the broad spectrum of neurocognitive deficits attributable to cerebrovascular disease, including cerebral ... More


Management of Mild Cognitive Impairment

Ramit Ravona-Springer and Amos D. Korczyn

in Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.003.0019
Subject:
Psychology, Neuropsychology

Mild cognitive impairment (MCI) is a prodromal syndrome often linked to the eventual emergence of dementia syndromes such as Alzheimer’s disease (AD) and vascular dementia (VaD). Research regarding ... More


Heterogeneity in Dementia and Mild Cognitive Impairment: Using Statistical Modeling Techniques

Deborah A. G. Drabick and Jill Rabinowitz

in Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.003.0007
Subject:
Psychology, Neuropsychology

Mild cognitive impairment (MCI) and dementia such as Alzheimer’s disease and vascular dementia are heterogeneous conditions that are associated with a chronic course and impairments across a ... More


The Meaning of Memory Loss: Illness, Identity, and Biography

Renée L. Beard

in Living with Alzheimer's: Managing Memory Loss, Identity, and Illness

Published in print:
2016
Published Online:
January 2017
ISBN:
9781479800117
eISBN:
9781479855377
Item type:
chapter
Publisher:
NYU Press
DOI:
10.18574/nyu/9781479800117.003.0002
Subject:
Social Work, Health and Mental Health

This introductory chapter presents the topic of the book, Alzheimer’s illness narratives, and outlines the remaining chapters. While AD is currently constructed as a problem of epidemic proportion, ... More


Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

David J. Libon, Melissa Lamar, Rodney A. Swenson, and Kenneth M. Heilman (eds)

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.001.0001
Subject:
Psychology, Neuropsychology

Alzheimer’s disease and vascular dementia are acknowledged as the two most common types of dementia. Each of these dementia syndromes are associated with prodromal clinical syndromes, often referred ... More


Vascular Risk Factors and Their Relationship to Brain Aging: Findings from the Framingham Heart Study

Ting Fang Alvin Ang, Prajakta Joshi, and Rhoda Au

in Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach

Published in print:
2020
Published Online:
June 2020
ISBN:
9780190634230
eISBN:
9780190634254
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190634230.003.0002
Subject:
Psychology, Neuropsychology

The Framingham Heart Study (FHS) was established in 1948 and is the longest, ongoing prospective cohort study studying cardiovascular diseases and stroke. Initially, the FHS was primarily focused on ... More


A Bubble Off

Frederick M. Barken

in Out of Practice: Fighting for Primary Care Medicine in America

Published in print:
2011
Published Online:
August 2016
ISBN:
9780801449765
eISBN:
9780801460609
Item type:
chapter
Publisher:
Cornell University Press
DOI:
10.7591/cornell/9780801449765.003.0006
Subject:
Public Health and Epidemiology, Public Health

This chapter discusses the prospects for primary care provided to patients with mild cognitive impairment (MCI). People with MCI have more than a benign degree of forgetfulness, yet they are not ... More


Dementia: Impaired Thinking and Judgment; Confusion

J. Eric Ahlskog

in Dementia with Lewy Body and Parkinson's Disease Patients: Patient, Family, and Clinician Working Together for Better Outcomes

Published in print:
2013
Published Online:
November 2020
ISBN:
9780199977567
eISBN:
9780197563342
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199977567.003.0020
Subject:
Clinical Medicine and Allied Health, Neurology

Dementia implies problems with cognition (thinking), and this is a fundamental component of DLB and PDD. Dementia also implies that the cognitive problems ... More


Challenges of Participating in Research About Living with Mild Cognitive Impairment Among Disabled Veterans

Christine Schneider and Eva Kahana

in Research Involving Participants with Cognitive Disability and Difference: Ethics, Autonomy, Inclusion, and Innovation

Published in print:
2019
Published Online:
October 2019
ISBN:
9780198824343
eISBN:
9780191863165
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198824343.003.0009
Subject:
Neuroscience, Behavioral Neuroscience, Techniques

This chapter provides insights from an ongoing study of elderly veterans’ experiences of living with newly diagnosed mild cognitive impairment (MCI). Recruitment for this qualitative study was ... More


The Social Construction of Dementia

Alison Wray

in The Dynamics of Dementia Communication

Published in print:
2020
Published Online:
April 2020
ISBN:
9780190917807
eISBN:
9780190917838
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190917807.003.0004
Subject:
Linguistics, Sociolinguistics / Anthropological Linguistics

This chapter considers how social attitudes and contexts shape interaction with people living with a dementia. These factors are termed ‘soft’ causes of dementia, because they affect people’s ... More


Virtual Reality for Assessment of Episodic Memory in Normal and Pathological Aging

Gaën Plancher and Pascale Piolino

in The Role of Technology in Clinical Neuropsychology

Published in print:
2017
Published Online:
November 2020
ISBN:
9780190234737
eISBN:
9780197559543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190234737.003.0015
Subject:
Computer Science, Virtual Reality

Memory is one of the most important cognitive functions in a person’s life. Memory is essential for recalling personal memories and for performing many ... More


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