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The nature of migraine: do we need to invoke slow neurochemical processes?

J.N. Blau

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0002
Subject:
Neuroscience, Disorders of the Nervous System

This chapter asks: What is migraine? The word ‘migraine’ needs clarifying because it can be used in two senses: clinical attacks and the underlying migraine processes. This chapter describes the ... More


Regional cerebral blood flow in migraine

Jes Olesen, Tom Skyhøj Olsen, and Lars Friberg

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0008
Subject:
Neuroscience, Disorders of the Nervous System

Several methods for measuring regional cerebral blood flow (rCBF) are now available. Each method and equipment has its own advantages and drawbacks. The xenon-133 (133Xe) inhalation or injection ... More


The biochemical basis of migraine predisposition

Vivette Glover and Merton Sandler

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0019
Subject:
Neuroscience, Disorders of the Nervous System

This chapter discusses some aspects of the biochemistry of migraine predisposition, and indicate how some of the initiating factors may interact with the central monoamine systems. Professor Lance ... More


The current status of migraine therapy

F. Clifford Rose

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0024
Subject:
Neuroscience, Disorders of the Nervous System

A recent method of preventing migraine attack has been tried on patients with premonitory symptoms, for example, irritability, excitement, euphoria, or food cravings that occur as long as twenty-four ... More


Contribution of experimental studies to understanding the pathophysiology of migraine

J.W. Lance, G.A. Lambert, P.J. Goadsby, and A.S. Zagami

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0003
Subject:
Neuroscience, Disorders of the Nervous System

For any hypothesis to be truly satisfying, it must be compatible with all the known facts. The manifestations of migraine are so diverse that one must resist the temptation to seize on some and ... More


The neurovascular basis of migraine: some concluding thoughts

James W. Lance

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0027
Subject:
Neuroscience, Disorders of the Nervous System

The migraine attack may start in the brain and affect the vascular system secondarily. Feedback from vessels to the brain completes a vicious circle. In the internal carotid circulation, the phase of ... More


General discussion II

Merton Sandler and Geralyn M. Collins

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0026
Subject:
Neuroscience, Disorders of the Nervous System

This article presents a general discussion focusing on the association between migraine and other symptoms such as tension headache and photophobia. There are now attempts to identify what is ... More


Behavioural effects of m-chlorophenylpiperazine (m-CPP), a reported migraine precipitant

G. Curzon, G.A. Kennett, K. Shah, and P. Whitton

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0013
Subject:
Neuroscience, Disorders of the Nervous System

The anxiogenic effect may be relevant to migraine, as anxiety or stress are candidates for precipitating attacks of migraine, and it is therefore of great interest that Brewerton et al. recently ... More


Peptidergic mechanisms in human intracranial and extracranial arteries

Lars Edvinsson, Inger Jansen, and Rolf Uddman

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0017
Subject:
Neuroscience, Disorders of the Nervous System

Migraine attacks are conventionally thought to involve a dysfunction in the regulation of tone in intra- and extracranial blood vessels. A number of agents have been suggested as responsible for the ... More


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