Tza‐Huei Wang, Kelvin Liu, Hsin‐Chih Yeh, and Christopher M. Puleo
- Published in print:
- 2010
- Published Online:
- September 2010
- ISBN:
- 9780199219698
- eISBN:
- 9780191594229
- Item type:
- chapter
- Publisher:
- Oxford University Press
- DOI:
- 10.1093/acprof:oso/9780199219698.003.0010
- Subject:
- Mathematics, Mathematical Biology
This chapter discusses and provides insight into state of the art nanobiosensors used in high sensitivity molecular analysis and detection. It begins with an introduction into the fundamental ...
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This chapter discusses and provides insight into state of the art nanobiosensors used in high sensitivity molecular analysis and detection. It begins with an introduction into the fundamental considerations of nanobiosensor design. To date, a myriad of sensors has been developed based on a wide array of nanomaterials using both optical and electrical signal transduction methods. Illustrative examples of various nanobiosensors based on metallic nanoparticles, semiconductor nanocrystals, and nanowire/nanotubes are given and organized according to the specific signal transduction mechanisms employed. Finally, single molecule detection methods are discussed as techniques to accurately analyze and quantify the output signal of fluorescent nanobiosensors. The chapter concludes with a brief prospective into the future of nanomaterials based sensing systems.Less
This chapter discusses and provides insight into state of the art nanobiosensors used in high sensitivity molecular analysis and detection. It begins with an introduction into the fundamental considerations of nanobiosensor design. To date, a myriad of sensors has been developed based on a wide array of nanomaterials using both optical and electrical signal transduction methods. Illustrative examples of various nanobiosensors based on metallic nanoparticles, semiconductor nanocrystals, and nanowire/nanotubes are given and organized according to the specific signal transduction mechanisms employed. Finally, single molecule detection methods are discussed as techniques to accurately analyze and quantify the output signal of fluorescent nanobiosensors. The chapter concludes with a brief prospective into the future of nanomaterials based sensing systems.
