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Mendelian randomization: the contribution of genetic epidemiology to elucidating environmentally modifiable causes of disease

George Davey Smith and Shah Ebrahim

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0021
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Conventional risk factor epidemiology — directly studying environmentally modifiable exposures that may influence disease risk — and genetic epidemiology have similarities and differences. The ... More


Theoretical underpinning for the use of intergenerational studies in life course epidemiology

Debbie A Lawlor, Sam Leary, and George Davey Smith

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0002
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Intergenerational studies have been widely used in life course epidemiology both to examine primary research hypotheses and to explore underlying mechanisms for established associations. This chapter ... More


Genetics in Dietary Analyses

Walter Willett

in Nutritional Epidemiology

Published in print:
2012
Published Online:
January 2013
ISBN:
9780199754038
eISBN:
9780199979448
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199754038.003.0014
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

Nutritionists have long known that differences exist among individuals in their responses to the same dietary change, and it was assumed that many of these differences were due to unmeasurable ... More


Genetic Epidemiology of Cancer

Christopher Haiman and David J. Hunter

in Textbook of Cancer Epidemiology

Published in print:
2018
Published Online:
February 2018
ISBN:
9780190676827
eISBN:
9780190676858
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190676827.003.0004
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

This chapter explores the genetic epidemiology of cancer: the identification and quantification of inherited genetic factors, and their potential interaction with the environment, in the etiology of ... More


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