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Life course influences on coronary heart disease

G. Davey Smith and J. Lynch

in Coronary Heart Disease Epidemiology: From aetiology to public health

Published in print:
2005
Published Online:
September 2009
ISBN:
9780198525738
eISBN:
9780191724114
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198525738.003.0034
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter outlines the concepts of life course epidemiology as applied to coronary heart disease (CHD), discusses evidence with regard to early life factors and CHD, and considers the recently ... More


Reproductive epidemiology

Jørn Olsen and Ellen Aagaard Nøhr

in Teaching Epidemiology: A guide for teachers in epidemiology, public health and clinical medicine

Published in print:
2010
Published Online:
May 2010
ISBN:
9780199239481
eISBN:
9780191716973
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199239481.003.020
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Reproductive health covers a broad category of health and disease conditions, according to the Cairo Statement. This chapter focuses on subfecundity fertility, fetal death, malformations, pregnancy ... More


Why family matters: an introduction

Debbie A Lawlor and Gita D Mishra

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Family characteristics and interactions can directly affect one's health and wellbeing across the life course. In addition to the importance of recruiting and collecting data on family members, ... More


Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Deborah A. Lawlor and Gita D. Mishra (eds)

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.001.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Family based studies, including intergenerational, sibling and twin studies, are increasingly used to explore life course epidemiology. However, understanding the underlying assumptions of these ... More


Introduction

Diana Kuh and Yoav Ben-Shlomo

in A Life Course Approach to Chronic Disease Epidemiology

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198578154
eISBN:
9780191724039
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198578154.003.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This introductory chapter provides an overview of adult risk factors and why interest in the early life origins for adult chronic disease emerged. It then discusses the growth of life course ... More


A life course approach to women’s health: does the past predict the present?

Diana Kuh and Rebecca Hardy

in A Life Course Approach to Women's Health

Published in print:
2002
Published Online:
September 2009
ISBN:
9780192632890
eISBN:
9780191723629
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192632890.003.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter begins with an overview of the central themes of this book. It then introduces life course epidemiology, which is the study of the contribution of biological and social factors acting ... More


The future of family-based studies in life course epidemiology: challenges and opportunities

Gita D Mishra and Debbie A Lawlor

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0017
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Family-based studies can provide a more comprehensive view of life course epidemiology than studies that do not engage with family effects. They can establish intergenerational associations, help to ... More


Using available family members as proxies to provide information on other family members who are difficult to reach

Susannah Tomkins

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0008
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

In life course epidemiology studies, the use of proxy (secondary) respondents may be an integral part of the study design or a consequence of not being able to reach or obtain information from the ... More


Life course epidemiology, ageing research, and maturing cohort studies: a dynamic combination for understanding healthy ageing

Diana Kuh, Marcus Richards, Rachel Cooper, Rebecca Hardy, and Yoav Ben-Shlomo

in A Life Course Approach to Healthy Ageing

Published in print:
2013
Published Online:
January 2014
ISBN:
9780199656516
eISBN:
9780191748042
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199656516.003.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Society views population ageing as a challenge at best, and as a social problem at worst, despite increased life expectancy being a notable human achievement. Population health trends show an ... More


Theoretical underpinning for the use of sibling studies in life course epidemiology

Kate W Strully and Gita D Mishra

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0003
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Siblings can have a great deal in common (e.g., parents, genes, early life home env1ironments, etc.), but they are also distinct individuals with unique personalities and physical traits. This ... More


How family-based studies have added to understanding the life course epidemiology of reproductive health

Susan MB Morton and Janet Rich Edwards

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0015
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Reproductive events throughout a woman's life course tend to be both a product of the cumulative exposures a woman has been subject to before that event, as well as a marker for her likely future ... More


Discussant chapter—summary of the theoretical approaches to family-based studies in life course epidemiology

Hazel M Inskip

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0005
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Chapters 2 to 4 describe three specific approaches to family studies, namely, intergenerational, sibling, and twin studies. All can be used to assist in distinguishing between genetic and ... More


Birth cohorts: a resource for life course studies

Anne-Marie Nybo Andersen, Mia Madsen, and Debbie A Lawlor

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0006
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter discusses issues concerned with the design and practicalities of setting up birth cohorts for life course epidemiology. The demand for a blueprint of the ideal birth cohort study is ... More


Discussant chapter—the practicalities of undertaking family-based studies

Rebecca Hardy and Diana Kuh

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0009
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter summarizes the origins of some of the existing life course studies and the current potential for using these studies to address family-based life course questions. It also highlights ... More


Family-based life course studies in low- and middle-income countries

G David Batty, Cesar G Victora, and Debbie A Lawlor

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0007
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter briefly describes the growing impact of non-communicable disease in low- and middle-income countries (LMIC) which, together with existing infectious illnesses and a rising incidence of ... More


How family-based studies have added to the understanding of life course epidemiology of mental health

Stephani L Hatch and Gita D Mishra

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0014
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter reviews some of the key family-based studies that have identified links between various illnesses and behaviours in parents and siblings with psychiatric disorders in study members. It ... More


Discussant chapter—using family-based designs in life course epidemiology

John Lynch and Seungmi Yang

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0016
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The three chapters in this section offer different but complementary conceptualizations of ‘family’. Morton and Rich Edwards used ‘family’ to document inter-generational concordance of reproductive ... More


Theoretical underpinning for the use of twin studies in life course epidemiology

Ruth J F Loos, Charlotte L Ridgway, and Ken K Ong

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0004
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The classical twin design is used in genetic epidemiology to estimate the heritability of a trait or disease. Despite potential biases for certain traits at specific stages during the life course, ... More


Family-based studies applied to the influence of early life factors on cardiovascular disease

Debbie A Lawlor and David A Leon

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0013
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

There is good evidence that associations exist between fetal and other early life factors and subsequent risk of cardiovascular disease (CVD) that can be replicated in a range of settings. These ... More


Statistical considerations in intergenerational studies

Dorothea Nitsch and Gita D Mishra

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0010
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Intergenerational data necessarily reflect the time and place that the different generations of participants were living in. This chapter aims first to introduce simple concepts to provide an ... More


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