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Leukaemia and myeloma

Peter Hoskin and Wendy Makin

in Oncology for Palliative Medicine

Published in print:
2003
Published Online:
November 2011
ISBN:
9780192628114
eISBN:
9780191730115
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192628114.003.0016
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter discusses myeloma and leukaemia, and their different types. The initial discussion in the chapter focuses on acute leukaemia, which occurs in two forms: acute lymphoblastic (ALL) and ... More


Childhood Cancer in Britain: Incidence, survival, mortality

Charles Stiller (ed.)

Published in print:
2007
Published Online:
September 2009
ISBN:
9780198520702
eISBN:
9780191723711
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520702.001.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Cancer is diagnosed in about 140 per million children in Britain each year. There is a 1 in 500 chance that a child will be affected in the first 15 years of life, the most frequently occurring types ... More


Do cancers cluster?

F. E. Alexander and P. Boyle

in Spatial Epidemiology: Methods and Applications

Published in print:
2001
Published Online:
September 2009
ISBN:
9780198515326
eISBN:
9780191723667
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198515326.003.0017
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter addresses the issue of cancer clustering with particular reference to childhood leukaemia. Clustering is a poorly defined concept in medical literature. A distinction must be made ... More


Geographical variations in childhood leukaemia incidence

J. F. Bithell and T. J. Vincent

in Spatial Epidemiology: Methods and Applications

Published in print:
2001
Published Online:
September 2009
ISBN:
9780198515326
eISBN:
9780191723667
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198515326.003.0018
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter examines geographical variations in the incidence of childhood leukaemia. It shows there is more variation of incidence at the international level than at smaller geographical scales of ... More


Childhood leukaemia around the Sellafield nuclear plant

M. J. Gardner

in Geographical and Environmental Epidemiology: Methods for Small Area Studies

Published in print:
1996
Published Online:
September 2009
ISBN:
9780192622358
eISBN:
9780191723636
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192622358.003.0025
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter presents a case study of childhood leukaemia around the Sellafield nuclear installation in England. The original reports of excess mortality spurred a number of inquiries, and led to a ... More


Stem cells

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0025
Subject:
Neuroscience, Techniques

Until fairly recently, interest in stem cells was restricted within neurobiology to studies on the fundamental principles of neural development, although in other fields (such as oncology) they have ... More


Management of acute leukaemias

Santiago Pavlovsky, Pablo Desmery, and María Cecilia Dignani

in Palliative Care Consultations in Haemato-oncology

Published in print:
2003
Published Online:
November 2011
ISBN:
9780198528081
eISBN:
9780191730399
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198528081.003.0003
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making

This chapter focuses on acute leukaemia, its management and treatment. Acute leukaemia is a clonal neoplastic disease characterised by the proliferation of immature cells of the haematopoietic ... More


Oral cancer

Max Robinson, Keith Hunter, Michael Pemberton, and Philip Sloan

in Soames' & Southam's Oral Pathology

Published in print:
2018
Published Online:
November 2020
ISBN:
9780199697786
eISBN:
9780191918483
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199697786.003.0008
Subject:
Clinical Medicine and Allied Health, Dentistry

The term ‘oral cancer’ encompasses all malignant neoplasms affecting the oral cavity. The majority, greater than 90%, are squamous cell car¬cinomas. The remainder are uncommon and comprise minor ... More


Production of targeted embryonic stem cell clones

Michael P. Matise and Alexandra L. Joyner

in Gene Targeting: A Practical Approach

Published in print:
1999
Published Online:
November 2020
ISBN:
9780199637928
eISBN:
9780191918162
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199637928.003.0007
Subject:
Chemistry, Organic Chemistry

The discovery that cloned DNA introduced into tissue culture cells can undergo homologous recombination at specific chromosomal loci has revolutionized our ability to study gene function in cell ... More


Production of chimeras by blastocyst and morula injection of targeted ES cells

Virginia Papaioannou and Randall Johnson

in Gene Targeting: A Practical Approach

Published in print:
1999
Published Online:
November 2020
ISBN:
9780199637928
eISBN:
9780191918162
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199637928.003.0008
Subject:
Chemistry, Organic Chemistry

The ability of mammalian embryos to incorporate foreign cells and develop as chimeras has been exploited for a variety of purposes including the elucidation of cell lineages, the investigation of ... More


Clinical Haematology and Oncology

Iqbal Khan (ed.)

in Best of Five MCQs for the MRCP Part 1 Volume 1

Published in print:
2017
Published Online:
November 2020
ISBN:
9780198746720
eISBN:
9780191916908
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198746720.003.0006
Subject:
Clinical Medicine and Allied Health, Professional Development in Medicine

Questions A 56-year-old woman with terminal breast cancer and spinal metastases comes to the emergency department. She complains of lower back pain and neuopathic pain going down her lefit leg. ... More


General medicine

Nicholas Longridge, Pete Clarke, Raheel Aftab, and Tariq Ali

Katharine Boursicot and David Sales (eds)

in Oxford Assess and Progress: Clinical Dentistry

Published in print:
2019
Published Online:
November 2020
ISBN:
9780198825173
eISBN:
9780191917301
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198825173.003.0020
Subject:
Clinical Medicine and Allied Health, Professional Development in Medicine

The oral cavity is the largest and most used orifice in the human body. It is the opening of the aerodigestive tract, as well as a region of the body that is heavily involved in both sensing the ... More


Acute joint pain

Hugo Farne, Edward Norris-Cervetto, and James Warbrick-Smith

in Oxford Cases in Medicine and Surgery

Published in print:
2015
Published Online:
November 2020
ISBN:
9780198716228
eISBN:
9780191916809
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198716228.003.0033
Subject:
Clinical Medicine and Allied Health, Surgery

The ‘must exclude’ diagnosis is septic arthritis. Not only can it destroy articular cartilage within days if not treated (hence permanently reducing joint function), but it is also associated ... More


Medical disability

M.T. Hosey and R. Welbury

in Paediatric Dentistry

Published in print:
2018
Published Online:
November 2020
ISBN:
9780198789277
eISBN:
9780191917103
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198789277.003.0025
Subject:
Clinical Medicine and Allied Health, Dentistry

There are many general medical conditions that can directly affect the provision of dental care and some where the consequences of dental disease, or even dental treatment, can be life-threatening. ... More


Novartis Trips Over Section 3(d)

Prashant Reddy T. and Sumathi Chandrashekaran

in Create, Copy, Disrupt: India's Intellectual Property Dilemmas

Published in print:
2017
Published Online:
March 2017
ISBN:
9780199470662
eISBN:
9780199088850
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199470662.003.0004
Subject:
Law, Intellectual Property, IT, and Media Law

One of the first high-profile patent cases after 2005 was the patent application filed by Novartis for the protection of Glivec, a sensational new drug which dramatically increased the survival rate ... More


Understanding Cancer

Cathy Hughes

in Adult Nursing Practice: Using evidence in care

Published in print:
2012
Published Online:
November 2020
ISBN:
9780199697410
eISBN:
9780191918476
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199697410.003.0014
Subject:
Clinical Medicine and Allied Health, Nursing

The aim of this chapter is provide an overview of cancer, a biologically similar, but diverse, group of diseases. Understanding the disease process will help the practising nurse to plan nursing ... More


Exam 6

Rebecca Hanlon, John Curtis, Hulya Wieshmann, David White, Caren Landes, and Val Gough

in Long Cases for the Final FRCR 2B

Published in print:
2011
Published Online:
November 2020
ISBN:
9780199590001
eISBN:
9780199590001
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199590001.003.0010
Subject:
Clinical Medicine and Allied Health, Professional Development in Medicine

Case 6.1 Clinical details A 70-year-old female patient with weight loss, dyspnoea, and cough. No improvement with antibiotics. No history of immune deficiency. Imaging Chest X-ray. Axial CT ... More


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