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Membrane Properties and Neurotransmitter Actions

DAVID A. McCORMICK

in The Synaptic Organization of the Brain

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195159561
eISBN:
9780199864447
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195159561.003.0002
Subject:
Neuroscience, Molecular and Cellular Systems, Development

This chapter provides a general overview of neuronal currents known to exist in brain cells, how they may be modulated by neurotransmitters, and how the interplay between the two can result in ... More


Equations Underlying the Axon Models

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0019
Subject:
Psychology, Cognitive Neuroscience

The Axon models present the fundamental concepts that underlie the generation and propagation of the nerve impulses. This chapter includes a complete list of the equations that describe the ... More


Basis of the Nerve Impulse

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0004
Subject:
Psychology, Cognitive Neuroscience

The rapid conduction of signals by neurons over distances greater than about 1 mm occurs almost exclusively by electrical impulses. This chapter presents the fundamental concepts that underlie the ... More


Axon Models

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0011
Subject:
Psychology, Cognitive Neuroscience

The Axon model simulates the equations and parameters derived from experiments by Hodgkin and Huxley on the squid giant axon. Because of the exact correspondence between the equations incorporated ... More


Single-channel properties and gating of Na+ and K+ channels in the squid giant axon

Francisco Bezanilla and Ana M. Correa

in Cephalopod Neurobiology: Neuroscience Studies in Squid, Octopus and Cuttlefish

Published in print:
1995
Published Online:
March 2012
ISBN:
9780198547907
eISBN:
9780191724299
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198547907.003.0090
Subject:
Neuroscience, Invertebrate Neurobiology

This chapter describes patch clamp recordings made from the inner membrane surface of the cut-open squid giant axon, allowing examination of macroscopic ionic currents, gating currents, and single ... More


The Cortical Neuron as an Electrophysiological Unit

Michael J. Gutnick and Wayne E. Crill

in The Cortical Neuron

Published in print:
1995
Published Online:
March 2012
ISBN:
9780195083309
eISBN:
9780199847464
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195083309.003.0003
Subject:
Neuroscience, Molecular and Cellular Systems

Cellular physiological studies from all areas of the brain have revealed that a rich assortment of ionic channels combine variously in the soma-dendritic membranes of different neurons to produce a ... More


Studies of the kinetics of the ionic and gating currents in the axons of Loligo forbesi as a guide to modelling of the sodium channel

Richard D. Keynes

in Cephalopod Neurobiology: Neuroscience Studies in Squid, Octopus and Cuttlefish

Published in print:
1995
Published Online:
March 2012
ISBN:
9780198547907
eISBN:
9780191724299
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198547907.003.0061
Subject:
Neuroscience, Invertebrate Neurobiology

This chapter summarizes the coming together of a new model of the voltage-gated sodium channel that successfully reconciles almost all the data obtained in recent years from a variety of experimental ... More


Tetrodotoxin affects sodium gating current in squid giant axon

Michinori Ichikawa and Gen Matsumoto

in Cephalopod Neurobiology: Neuroscience Studies in Squid, Octopus and Cuttlefish

Published in print:
1995
Published Online:
March 2012
ISBN:
9780198547907
eISBN:
9780191724299
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198547907.003.0084
Subject:
Neuroscience, Invertebrate Neurobiology

Molecular rearrangements of the sodium channels associated with membrane depolarization can be electrophysiologically studied by the analysis of the single-channel records or, more directly, by ... More


Modeling Voltage-Dependent Channels

Alain Destexhe and John R. Huguenard

in Computational Modeling Methods for Neuroscientists

Published in print:
2009
Published Online:
August 2013
ISBN:
9780262013277
eISBN:
9780262258722
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262013277.003.0006
Subject:
Neuroscience, Techniques

This chapter describes the voltage-gated ion channels. It considers the different types of formalisms in modeling ionic currents as the action potential and voltage-clamp recordings of the T-type ... More


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