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Physiological integration of innate immunity

David Schneider

in Insect Infection and Immunity: Evolution, Ecology, and Mechanisms

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199551354
eISBN:
9780191720505
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199551354.003.0007
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

Understanding how insect immunity is regulated requires studying the interactions of all those aspects of physiology that impact immunity. This includes both resistance and tolerance aspects of ... More


Immunology, Self and Nonself

Thomas Pradeu and Elizabeth Vitanza

in The Limits of the Self: Immunology and Biological Identity

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199775286
eISBN:
9780199932818
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199775286.003.0002
Subject:
Philosophy, Philosophy of Science, Metaphysics/Epistemology

This chapter investigates the different definitions of immunology, in particular the dominant definition stating that immunology is the discipline that studies the defense of organisms against ... More


In Defense of Self: How the Immune System Really Works

William R. Clark

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.001.0001
Subject:
Biology, Disease Ecology / Epidemiology

The immune system is the only thing standing between us and a world of microbial predators that could send us to an early and ugly death. It would be our only defense during the first hours of a ... More


The Immune Response to Infectious Disease: All Out War!

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0005
Subject:
Biology, Disease Ecology / Epidemiology

This chapter deals with the body's response to disease caused by infection with bacteria, viruses, or other microbes. The fundamental response is based on inflammation, which is mediated by the ... More


First Defense: The Immune System and Bioterrorism

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0014
Subject:
Biology, Disease Ecology / Epidemiology

During the first 48–72 hours of a bioterrorist attack using pathogenic microbes, the immune system will be our primary means of defense against potentially fatal disease. This chapter looks at the ... More


The natural history of defences

Paul Schmid-Hempel

in Evolutionary Parasitology: The Integrated Study of Infections, Immunology, Ecology, and Genetics

Published in print:
2021
Published Online:
September 2021
ISBN:
9780198832140
eISBN:
9780191870873
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198832140.003.0004
Subject:
Biology, Disease Ecology / Epidemiology, Evolutionary Biology / Genetics

Hosts can avoid infections by behavioural changes and by body walls. After infection, hosts can change their behaviours to reduce the effects of parasitism. Immune defences have different arms ... More


Sleep, inflammation, and disease

M.A. Miller and F.P. Cappuccio

in Sleep, Health and Society: From Aetiology to Public Health

Published in print:
2010
Published Online:
January 2011
ISBN:
9780199566594
eISBN:
9780191595066
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199566594.003.0011
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Sleep is a fundamental requirement for living individuals. Emerging evidence suggests that disturbances in sleep and sleep disorders play a role in the morbidity of chronic conditions including ... More


Echinoderm diseases and pathologies

L. Courtney Smith, S. Anne Boettgerm, Maria Byrne, Andreas Heyland, Diana L. Lipscombe, Audrey J. Majeske, Jonathan P. Rast, Nicholas W. Schuh, Linsheng Song, Ghada Tafesh-Edwards, Lingling Wang, Zhuang Xue, and Zichao Yu

in Invertebrate Pathology

Published in print:
2022
Published Online:
March 2022
ISBN:
9780198853756
eISBN:
9780191888182
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198853756.003.0018
Subject:
Biology, Disease Ecology / Epidemiology, Animal Biology

Echinoderms are basal deuterostomes and the sister phylum to the chordates. All are marine animals with effective and robust innate immunity. Echinoderms are host to diseases in both larvae and ... More


Rapid evolution of innate immune response genes

Brian P. Lazzaro and Andrew G. Clark

in Rapidly Evolving Genes and Genetic Systems

Published in print:
2012
Published Online:
December 2013
ISBN:
9780199642274
eISBN:
9780191774751
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199642274.003.0020
Subject:
Biology, Evolutionary Biology / Genetics

The opportunity for arms-race evolution between host and pathogens is one reason why genes involved in immune functions are often rapidly evolving. Innate immune systems lack the degree of pathogen ... More


Our inner defense systems

Mats Lekander

in The Inflamed Feeling: The Brain's Role in Immune Defence

Published in print:
2022
Published Online:
February 2022
ISBN:
9780198863441
eISBN:
9780191895937
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198863441.003.0003
Subject:
Psychology, Behavioural Neuroendocrinology, Clinical Psychology

The chapter describes the central functioning of the immune system, making clear how the substantial threat from microorganisms needs to be handled through a multitude of mechanisms. The basic ... More


Sjögren’s and the Immune System

Robert I. Fox and Steven E. Carsons

in The Sjögren's Book

Published in print:
2022
Published Online:
May 2022
ISBN:
9780197502112
eISBN:
9780197650417
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780197502112.003.0006
Subject:
Psychology, Health Psychology

Sjögren’s disease is an autoimmune disorder in which environmental, genetic, and hormonal factors result in the disruption of the body’s innate and acquired immune systems. The activation of ... More


Recent and Promising Scientific Developments

Steven E. Carsons, Mabi Singh, Nancy McNamara, and Katherine M. Hammitt

in The Sjögren's Book

Published in print:
2022
Published Online:
May 2022
ISBN:
9780197502112
eISBN:
9780197650417
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780197502112.003.0048
Subject:
Psychology, Health Psychology

After many years with little forward movement in Sjögren’s, promising approaches to disease management are on the horizon, including biomarker discoveries, new metrics to assess disease activity, and ... More


Diseases of chelicerates

Christopher J. Coates

in Invertebrate Pathology

Published in print:
2022
Published Online:
March 2022
ISBN:
9780198853756
eISBN:
9780191888182
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198853756.003.0009
Subject:
Biology, Disease Ecology / Epidemiology, Animal Biology

Chelicerates represent one of the oldest and second most speciose groups within the Phylum Arthropoda. Often referred to as ‘living fossils’, extant chelicerates inhabit terrestrial and aquatic ... More


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