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Physiological integration of innate immunity

David Schneider

in Insect Infection and Immunity: Evolution, Ecology, and Mechanisms

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199551354
eISBN:
9780191720505
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199551354.003.0007
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

Understanding how insect immunity is regulated requires studying the interactions of all those aspects of physiology that impact immunity. This includes both resistance and tolerance aspects of ... More


Immunology, Self and Nonself

Thomas Pradeu and Elizabeth Vitanza

in The Limits of the Self: Immunology and Biological Identity

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199775286
eISBN:
9780199932818
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199775286.003.0002
Subject:
Philosophy, Philosophy of Science, Metaphysics/Epistemology

This chapter investigates the different definitions of immunology, in particular the dominant definition stating that immunology is the discipline that studies the defense of organisms against ... More


In Defense of Self: How the Immune System Really Works

William R. Clark

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.001.0001
Subject:
Biology, Disease Ecology / Epidemiology

The immune system is the only thing standing between us and a world of microbial predators that could send us to an early and ugly death. It would be our only defense during the first hours of a ... More


The Immune Response to Infectious Disease: All Out War!

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0005
Subject:
Biology, Disease Ecology / Epidemiology

This chapter deals with the body's response to disease caused by infection with bacteria, viruses, or other microbes. The fundamental response is based on inflammation, which is mediated by the ... More


First Defense: The Immune System and Bioterrorism

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0014
Subject:
Biology, Disease Ecology / Epidemiology

During the first 48–72 hours of a bioterrorist attack using pathogenic microbes, the immune system will be our primary means of defense against potentially fatal disease. This chapter looks at the ... More


Sleep, inflammation, and disease

M.A. Miller and F.P. Cappuccio

in Sleep, Health and Society: From Aetiology to Public Health

Published in print:
2010
Published Online:
January 2011
ISBN:
9780199566594
eISBN:
9780191595066
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199566594.003.0011
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Sleep is a fundamental requirement for living individuals. Emerging evidence suggests that disturbances in sleep and sleep disorders play a role in the morbidity of chronic conditions including ... More


Rapid evolution of innate immune response genes

Brian P. Lazzaro and Andrew G. Clark

in Rapidly Evolving Genes and Genetic Systems

Published in print:
2012
Published Online:
December 2013
ISBN:
9780199642274
eISBN:
9780191774751
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199642274.003.0020
Subject:
Biology, Evolutionary Biology / Genetics

The opportunity for arms-race evolution between host and pathogens is one reason why genes involved in immune functions are often rapidly evolving. Innate immune systems lack the degree of pathogen ... More


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