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Stem Cell Research

Bonnie Steinbock

in Life Before Birth: The Moral and Legal Status of Embryos and Fetuses

Published in print:
2011
Published Online:
September 2011
ISBN:
9780195341621
eISBN:
9780199897131
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195341621.003.0014
Subject:
Philosophy, Moral Philosophy, Philosophy of Science

Human embryonic stem cell (hESC) research involves the destruction of embryos. On the interest view, embryos lack moral standing, but research that kills embryos is deeply offensive to many people. ... More


Reprogramming Cells

Sheldon Krimsky

in Stem Cell Dialogues: A Philosophical and Scientific Inquiry Into Medical Frontiers

Published in print:
2015
Published Online:
November 2015
ISBN:
9780231167482
eISBN:
9780231539401
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231167482.003.0012
Subject:
Biology, Bioethics

In this dialogue, Dr. Rebecca Franklin and Dr. Frederick Jones, a stem cell biologist, discuss the prospects of cell reprogramming for producing therapeutic stem cells. The process of reprogramming ... More


Circumventing Embryocide

Sheldon Krimsky

in Stem Cell Dialogues: A Philosophical and Scientific Inquiry Into Medical Frontiers

Published in print:
2015
Published Online:
November 2015
ISBN:
9780231167482
eISBN:
9780231539401
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231167482.003.0007
Subject:
Biology, Bioethics

In this dialogue, Dr. Rebecca Franklin and Catholic bioethicist Paul Flannery discuss the alternatives to destroying human embryos in order to acquire pluripotent stem cells. After President George ... More


Embryos without Ovaries

Sheldon Krimsky

in Stem Cell Dialogues: A Philosophical and Scientific Inquiry Into Medical Frontiers

Published in print:
2015
Published Online:
November 2015
ISBN:
9780231167482
eISBN:
9780231539401
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231167482.003.0023
Subject:
Biology, Bioethics

This dialogue provides a fictional account of a lecture series featuring Francis Davenport, a stem cell scientist, and Laura Murphy, a Catholic-educated Ph.D. bioethicist who specializes in ... More


Nuclear reprogramming and induced pluripotency

John C. Lucchesi

in Epigenetics, Nuclear Organization & Gene Function: With implications of epigenetic regulation and genetic architecture for human development and health

Published in print:
2019
Published Online:
March 2019
ISBN:
9780198831204
eISBN:
9780191869266
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198831204.003.0018
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

Four core transcription factors known to maintain the pluripotent state in embryonic stem cells (ESCs)—Oct4, Sox2, Klf4 and c-Myc—were used to induce pluripotent stem cells in adult-derived ... More


Regenerating Life

John Parrington

in Redesigning Life: How genome editing will transform the world

Published in print:
2020
Published Online:
December 2020
ISBN:
9780198766834
eISBN:
9780191918957
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198766834.003.0009
Subject:
Biology, Evolutionary Biology / Genetics

Stem cells, which are ‘immortal’ cells that divide indefinitely and produce many different cell types, are central to how our body develops and maintains itself. Embryonic stem cells can give rise to ... More


Cloning Animals, Cells, and Genes: Where Did Cloning Come From, and Where Is It Going To Right Now?

Scott Gilbert

in Fear, Wonder, and Science in the New Age of Reproductive Biotechnology

Published in print:
2017
Published Online:
January 2019
ISBN:
9780231170949
eISBN:
9780231544580
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231170949.003.0007
Subject:
Biology, Bioethics

Every technology has its history, and this chapter looks at the technologies of animal cloning and how they changed when it became apparent that one could perform some of the medical task of cloning ... More


Reversing Macular Degeneration

Sheldon Krimsky

in Stem Cell Dialogues: A Philosophical and Scientific Inquiry Into Medical Frontiers

Published in print:
2015
Published Online:
November 2015
ISBN:
9780231167482
eISBN:
9780231539401
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231167482.003.0010
Subject:
Biology, Bioethics

In this dialogue, Dr. Rebecca Franklin is having a conversation with Ben Townsend, a stem cell scientist, and his mother Barbara Townsend, a professor emeritus in the history of medicine at the ... More


Epilogue

Sheldon Krimsky

in Stem Cell Dialogues: A Philosophical and Scientific Inquiry Into Medical Frontiers

Published in print:
2015
Published Online:
November 2015
ISBN:
9780231167482
eISBN:
9780231539401
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231167482.003.0026
Subject:
Biology, Bioethics

This book has explored the science and ethics behind stem cells, as well as the excitement and optimism within the scientific community about the role stem cells would someday play in treating human ... More


Using a Stem Cell-Based Approach to Model Neurodegenerative Disease: Where Do We Stand?

Lee L. Rubin

in Translational Neuroscience: Toward New Therapies

Published in print:
2015
Published Online:
September 2016
ISBN:
9780262029865
eISBN:
9780262329859
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029865.003.0011
Subject:
Neuroscience, Research and Theory

Interest in improving methods to study human disease is rapidly growing, with the goal of providing effective therapeutics for serious, complex disorders. Following the discovery of cellular ... More


How Might We Get from Genes to Circuits to Disease?

Tobias Kaiser, Yuan Mei, and Guoping Feng

in Translational Neuroscience: Toward New Therapies

Published in print:
2015
Published Online:
September 2016
ISBN:
9780262029865
eISBN:
9780262329859
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029865.003.0008
Subject:
Neuroscience, Research and Theory

Recent advances in the identification of risk genes for psychiatric disorders have set the stage for functional interrogation of disease related-circuits and underlying mechanisms of pathophysiology. ... More


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