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Neurotrophic factors and their receptors: Roles in neuronal development and function

Louis F. Reichardt and Fariñas Isabel

in Molecular and Cellular Approaches to Neural Development

Published in print:
1998
Published Online:
May 2009
ISBN:
9780195111668
eISBN:
9780199865833
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195111668.003.0006
Subject:
Neuroscience, Molecular and Cellular Systems, Development

Neurotrophic factors are important regulators of the development and maintenance of vertebrate nervous system. During the development of the nervous system, neuronal populations undergo a process of ... More


Total Factor Productivity

R. C. O. Matthews, C. H. Feinstein, and J. C. Odling‐Smee

in British Economic Growth 1856-1973: The Post-War Period in Historical Perspective

Published in print:
1982
Published Online:
November 2003
ISBN:
9780198284536
eISBN:
9780191596629
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/0198284535.003.0007
Subject:
Economics and Finance, Economic History

The rates of growth of total factor input (TFI) and total factor productivity (TFP) are the “sources” of output growth only in a proximate sense. Despite their imperfections, these concepts remain a ... More


Signaling Molecules: The First Growth Factor

Gordon M. Shepherd

in Creating Modern Neuroscience: The Revolutionary 1950s

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.003.0003
Subject:
Neuroscience, History of Neuroscience

This chapter details early studies on the development of nerve cells. The nervous system arises from a single fertilized egg. Classical histologists visualized this process through the cells of the ... More


Mechanisms controlling the development of cortical connections at the target

David J. Price and David J. Willshaw

in Mechanisms of Cortical Development

Published in print:
2000
Published Online:
January 2010
ISBN:
9780192624277
eISBN:
9780191723735
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192624277.003.0006
Subject:
Neuroscience, Development

The preceding chapters have described how the embryonic anatomy of the early forebrain is established under the control of regulatory genes and extracellular signalling molecules. This chapter ... More


Gene Therapy Toward Clinical Application in the Cardiovascular Field

Hironori Nakagami, Mariana Kiomy Osako, and Ryuichi Morishita

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0020
Subject:
Neuroscience, Molecular and Cellular Systems

This chapter discusses the results of a study which assessed the potential of hepatocyte growth factor as a powerful angiogenic factor for treating peripheral arterial disease. It describes a novel ... More


Sleep Modulation of the Expression of Plasticity Markers

James M. Krueger, Ferenc Obál Jr., Joseph W. Harding, John W. Wright, and Lynn Churchill

in Sleep and Brain Plasticity

Published in print:
2003
Published Online:
September 2009
ISBN:
9780198574002
eISBN:
9780191724145
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198574002.003.0018
Subject:
Neuroscience, Behavioral Neuroscience

This chapter shows that various compounds (such as NO and various hormones, and cytokines) share three main functional features. They are released in response to neural activity; they are somnogenic; ... More


Creating Modern Neuroscience: The Revolutionary 1950s

Gordon M. Shepherd MD, DPhil

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.001.0001
Subject:
Neuroscience, History of Neuroscience

For modern scientists, history often starts with last week's journals and is regarded as largely a quaint interest compared with the advances of today. However, this book makes the case that, ... More


Roger W. Sperry and Rita Levi-Montalcini: From Neural Growth to “Split Brains”

Stanley Finger

in Minds Behind the Brain: A history of the pioneers and their discoveries

Published in print:
2005
Published Online:
January 2010
ISBN:
9780195181821
eISBN:
9780199865277
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195181821.003.0017
Subject:
Neuroscience, History of Neuroscience

Roger W. Sperry earned a reputation for his ability to design critical experiments that demanded looking at the growing and functioning nervous system in new ways. Sperry's most important discoveries ... More


Growth Regulation

Jyotsna Keni and Anna Pawlikowska–Haddal

in Textbook of Endocrine Physiology

Published in print:
2011
Published Online:
November 2020
ISBN:
9780199744121
eISBN:
9780197563045
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199744121.003.0014
Subject:
Clinical Medicine and Allied Health, Endocrinology and Diabetes

While multiple hormones influence somatic growth, the main regulator of postnatal growth is growth hormone. Growth hormone (GH) is secreted in a pulsatile manner from the anterior pituitary ... More


Glutamatergic Signaling In Neurogenesis

Noritaka Nakamichi and Yukio Yoneda

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0011
Subject:
Neuroscience, Molecular and Cellular Systems

This chapter summarizes recent studies on the functional expression of ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs) by neural progenitor cells isolated from ... More


Development of the nociceptor phenotype: role of nerve growth factor

Mendell Lorne M.

in Neurobiology of Nociceptors

Published in print:
1996
Published Online:
March 2012
ISBN:
9780198523345
eISBN:
9780191724527
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523345.003.0019
Subject:
Neuroscience, Sensory and Motor Systems

The notion that specialized nociceptors exist among the afferent fibre population is a relatively recent one. Although indirect evidence for the existence of these fibres had been available for many ... More


Trophic factors

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0009
Subject:
Neuroscience, Techniques

The developing nervous system produces about twice as many neurons as will survive into adulthood, and then at the end of development, around the time of birth in mammals, there is a short period ... More


Dendrite development

Jennifer Bestman, Jorge Santos Da Silva, and Hollis T. Cline

in Dendrites

Published in print:
2007
Published Online:
March 2012
ISBN:
9780198566564
eISBN:
9780191724206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566564.003.0003
Subject:
Neuroscience, Molecular and Cellular Systems

The emergence of dendritic arbor structure in vivo occurs in the context of a developing functional nervous system. It is therefore of utmost importance to consider the interaction between ... More


Nerve Growth Factor and Alzheimer’s Disease: New Twists to an Old Story

Cattaneo Antonino

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0026
Subject:
Neuroscience, Research and Theory

This chapter describes the connection between the nerve growth factor (NGF) and Alzheimer’s disease (AD). It reveals that NGF can be considered as an anti-amyloidogenic factor that normally keeps the ... More


Delivery of Molecular Agents in Tissue Engineering

W. Mark Saltzman

in Tissue Engineering: Engineering Principles for the Design of Replacement Organs and Tissues

Published in print:
2004
Published Online:
November 2020
ISBN:
9780195141306
eISBN:
9780197561775
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195141306.003.0017
Subject:
Chemistry, Medicinal Chemistry

The previous chapter provided some examples of tissue engineering, in which cells that were isolated and engineered outside of the body are introduced into a patient by direct injection of a cell ... More


Neurotrophins as Regulators of Visual Cortical Plasticity

Castrén Eero and Fernando Maya Vetencourt José

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0027
Subject:
Neuroscience, Research and Theory

This chapter describes neurotrophins as regulators of visual cortical plasticity. It illustrates that brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) are popular candidate ... More


Wound Healing In Glaucoma

Kimberly A. Mankiewicz, Leonard K. Seibold, Malik Y. Kahook, and Mark B. Sherwood

in Complications of Glaucoma Surgery

Published in print:
2013
Published Online:
November 2020
ISBN:
9780195382365
eISBN:
9780197562703
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195382365.003.0013
Subject:
Clinical Medicine and Allied Health, Ophthalmology

The goal of wound healing in most surgeries is to bring the injured tissue back to its original state to prevent the wound from reopening. However, in glaucoma surgery, the goal is to have ... More


The Posterior Pituitary and Water Metabolism

Willis K. Samson

in Textbook of Endocrine Physiology

Published in print:
2011
Published Online:
November 2020
ISBN:
9780199744121
eISBN:
9780197563045
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199744121.003.0009
Subject:
Clinical Medicine and Allied Health, Endocrinology and Diabetes

The neurohypophysis, also called the posterior pituitary or neural lobe , is the ventral extension of hypothalamic tissue derived from a developmental down growth of the neuroectoderm forming the ... More


The Thyroid

Ildiko Lingvay and Shelby A. Holt

in Textbook of Endocrine Physiology

Published in print:
2011
Published Online:
November 2020
ISBN:
9780199744121
eISBN:
9780197563045
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199744121.003.0015
Subject:
Clinical Medicine and Allied Health, Endocrinology and Diabetes

The thyroid gland, which is the largest endocrine organ, secretes primarily thyroid hormones that play a critical role in the normal growth and development of the maturing human. In the adult, ... More


Innervation: The Body’s Internet

Kenneth Douglas

in Bioprinting: To Make Ourselves Anew

Published in print:
2021
Published Online:
June 2021
ISBN:
9780190943547
eISBN:
9780197558164
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190943547.003.0006
Subject:
Biology, Biotechnology

Abstract: This chapter informs the reader of the discovery of nerve growth factor, how it plays an important role in bioprinting by directing the growth of the axons of nerve cells along specific ... More


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