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Life eternal in the face of senescence

Geoffrey E. Hill

in Mitonuclear Ecology

Published in print:
2019
Published Online:
June 2019
ISBN:
9780198818250
eISBN:
9780191859465
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198818250.003.0006
Subject:
Biology, Ecology, Evolutionary Biology / Genetics

Unlike prokaryotes, eukaryotes are born, mature, grow old, and die. Why death is inevitable for all complex life is among the most important questions in evolutionary biology. The mitochondrial ... More


Hereditary Neoplastic Syndromes

NORALANE M. LINDOR, CARL J. LINDOR, and MARK H. GREENE

in Cancer Epidemiology and Prevention

Published in print:
2006
Published Online:
September 2009
ISBN:
9780195149616
eISBN:
9780199865062
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195149616.003.0028
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The recent clinical availability of germ-line mutation testing for susceptibility genes related to the hereditary forms of common tumors such as breast, ovary, colorectum, and melanoma has served as ... More


Genetics, Cloning, and Stem Cell Research

Adil E. Shamoo and David B. Resnik

in Responsible Conduct of Research

Published in print:
2009
Published Online:
May 2009
ISBN:
9780195368246
eISBN:
9780199867615
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195368246.003.0014
Subject:
Biology, Disease Ecology / Epidemiology, Biochemistry / Molecular Biology

This chapter provides an overview of ethical, social, and policy issues related to research on human genetics and embryonic stem cells. It covers such topics as genetic engineering of animals and ... More


Germinal Selection: A Weismannian Solution to Lamarckian Problematics

Charlotte Weissman

in Transformations of Lamarckism: From Subtle Fluids to Molecular Biology

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015141
eISBN:
9780262295642
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015141.003.0006
Subject:
Biology, Evolutionary Biology / Genetics

This chapter analyzes August Weismann's theory of germinal selection—a process of competition and selection among the hereditary units within the germplasm. He argued that the germ line was not ... More


Transgenerational Epigenetic Inheritance

Eva Jablonka and Marion J. Lamb

in Evolution—the Extended Synthesis

Published in print:
2010
Published Online:
August 2013
ISBN:
9780262513678
eISBN:
9780262315142
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262513678.003.0007
Subject:
Biology, Evolutionary Biology / Genetics

This chapter reports the case of transgenerational epigenetic inheritance. It concentrates on developmental biology, in particular on molecular studies of epigenetics, and on one specific challenge: ... More


Why Did the Modern Synthesis Give Short Shrift to “Soft Inheritance”?

Adam Wilkins

in Transformations of Lamarckism: From Subtle Fluids to Molecular Biology

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015141
eISBN:
9780262295642
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015141.003.0013
Subject:
Biology, Evolutionary Biology / Genetics

This chapter presents three important reasons why evolutionary biologists dismissed Lamarckism or soft inheritance from the Modern Synthesis. The first is the legacy of adhering to August Weismann's ... More


Levels and Transitions

Peter Godfrey-Smith

in Darwinian Populations and Natural Selection

Published in print:
2009
Published Online:
May 2015
ISBN:
9780199552047
eISBN:
9780191810350
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:osobl/9780199552047.003.0006
Subject:
Philosophy, Moral Philosophy

This chapter explains the notion that Darwinian processes occur at different levels. Darwin defines population as a collection of entities in which there is variation in character, composed of the ... More


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