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Novel molecules

Andreas Wagner

in The Origins of Evolutionary Innovations: A Theory of Transformative Change in Living Systems

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199692590
eISBN:
9780191774829
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199692590.003.0066
Subject:
Biology, Evolutionary Biology / Genetics

A growing body of evidence points to the existence of genotype networks in both protein and RNA phenotypes, and to their importance for evolutionary innovation. This evidence comes from comparative ... More


Towards continuous genotype spaces

Andreas Wagner

in The Origins of Evolutionary Innovations: A Theory of Transformative Change in Living Systems

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199692590
eISBN:
9780191774829
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199692590.003.0240
Subject:
Biology, Evolutionary Biology / Genetics

Many systems are best viewed as having a continuous range of phenotypes. These include the continuous spectrum of conformations that molecules form through thermal noise, and the many macroscopic ... More


Evolutionary constraints and genotype spaces

Andreas Wagner

in The Origins of Evolutionary Innovations: A Theory of Transformative Change in Living Systems

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199692590
eISBN:
9780191774829
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199692590.003.0206
Subject:
Biology, Evolutionary Biology / Genetics

An evolutionary constraint is a bias or limitation in genotypic or phenotypic variation that a biological system produces. Striking phenotypic examples include the absence of photosynthesis in higher ... More


The role of recombination

Andreas Wagner

in The Origins of Evolutionary Innovations: A Theory of Transformative Change in Living Systems

Published in print:
2011
Published Online:
December 2013
ISBN:
9780199692590
eISBN:
9780191774829
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199692590.003.0177
Subject:
Biology, Evolutionary Biology / Genetics

Recombination causes long jumps through a vast genotype space. Because different regions of this space contain different novel phenotypes, recombination can thus greatly facilitate the exploration of ... More


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