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SNPs, HapMap, and common disease

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0009
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

The extent of single nucleotide polymorphism is reviewed, together with insights gained into the nature of allelic architecture in terms of haplotypes, linkage disequilibrium and recombination. The ... More


Concluding remarks and future directions

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0015
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

This final chapter seeks to provide a brief overview of some of the important insights that have been established from work investigating human genetic diversity. The remarkable range of human ... More


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