Jump to ContentJump to Main Navigation

You are looking at 1-20 of 78 items

  • Keywords: genetic variation x
Clear All Modify Search

View:

Evolutionary Conservation Genetics

Jacob Höglund

Published in print:
2009
Published Online:
May 2009
ISBN:
9780199214211
eISBN:
9780191706660
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199214211.001.0001
Subject:
Biology, Biodiversity / Conservation Biology, Evolutionary Biology / Genetics

Conservation genetics focuses on understanding the role and requirement of genetic variation for population persistence. However, considerable debate now surrounds the role of genetic factors (as ... More


Population genetics: Population and conservation genetics of canids

Robert K. Wayne, Eli Geffen, and Carles Vilà

in The Biology and Conservation of Wild Canids

Published in print:
2004
Published Online:
September 2007
ISBN:
9780198515562
eISBN:
9780191705632
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198515562.003.0003
Subject:
Biology, Biodiversity / Conservation Biology

This chapter discusses patterns of genetic variation and subdivision in a wide variety of canids. The influence of demographic history and ecological and topographic barriers on levels of variation, ... More


Reproductive ecology and genetic variation

Adrian C. Newton

in Forest Ecology and Conservation: A Handbook of Techniques

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198567448
eISBN:
9780191717895
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198567448.003.0006
Subject:
Biology, Plant Sciences and Forestry

This chapter first considers the process of flowering phenology and pollination, and techniques for measuring fruit production, dispersal, and predation. It then presents methods for analysing the ... More


The Genetics of Exotic Bird Introductions

Tim M. Blackburn, Julie L. Lockwood, and Phillip Cassey

in Avian Invasions: The Ecology and Evolution of Exotic Birds

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199232543
eISBN:
9780191715983
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199232543.003.0008
Subject:
Biology, Ornithology, Biodiversity / Conservation Biology

This chapter considers the long-term outcomes of exotic bird establishment in terms of the propensity for evolution in exotic bird populations. It shows that exotic birds have occasionally lost ... More


Human Genetic Diversity: Functional Consequences for Health and Disease

Julian C. Knight

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.001.0001
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

This book describes the remarkable progress which has been made in defining the extent and nature of human genetic variation, and its many consequences for us as individuals and in understanding ... More


Genes under selection: Mhc and others

Jacob Höglund

in Evolutionary Conservation Genetics

Published in print:
2009
Published Online:
May 2009
ISBN:
9780199214211
eISBN:
9780191706660
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199214211.003.0005
Subject:
Biology, Biodiversity / Conservation Biology, Evolutionary Biology / Genetics

This chapter focuses on genes under selection. Much of what is known about ‘ecologically relevant’ genetic variation at the level of DNA sequences comes from studies of genes of the major ... More


The extinction vortex, is genetic variation related to extinction?

Jacob Höglund

in Evolutionary Conservation Genetics

Published in print:
2009
Published Online:
May 2009
ISBN:
9780199214211
eISBN:
9780191706660
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199214211.003.0001
Subject:
Biology, Biodiversity / Conservation Biology, Evolutionary Biology / Genetics

This chapter begins with a brief introduction to the focus of this book, which is the idea that extinction of species is somehow related to loss of genetic variation. Theoretical considerations ... More


Lessons from haemoglobin

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0001
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

Study of genetic variation at the globin genes has provided a series of fundamental insights the nature and extent of genetic diversity and its functional consequences. This chapter provides a primer ... More


Domestication

Ádám Miklósi

in Dog Behaviour, Evolution, and Cognition

Published in print:
2007
Published Online:
January 2008
ISBN:
9780199295852
eISBN:
9780191711688
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199295852.003.0005
Subject:
Biology, Animal Biology

This chapter deals with one of the most long-debated question about how dogs became domesticated. Traditional understanding of this process was based on the finding of archaeologists that are, ... More


Concluding remarks and future directions

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0015
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

This final chapter seeks to provide a brief overview of some of the important insights that have been established from work investigating human genetic diversity. The remarkable range of human ... More


Finding genes and specific genetic variants responsible for disease

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0002
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

In this chapter different approaches to defining the genetic basis of disease are introduced including linkage analysis, positional cloning, linkage disequilibrium mapping and genetic association ... More


Who Let the Dogs in?: The Domestication of Animals and Plants

Norman A. Johnson

in Darwinian Detectives: Revealing the Natural History of Genes and Genomes

Published in print:
2007
Published Online:
September 2007
ISBN:
9780195306750
eISBN:
9780199790203
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195306750.003.0011
Subject:
Biology, Evolutionary Biology / Genetics

This chapter explores the timing of and evolutionary forces involved in our domestication of animals and plants. How many and which genes were involved? How long ago did these changes occur? Can we ... More


How to measure genetic variation

Jacob Höglund

in Evolutionary Conservation Genetics

Published in print:
2009
Published Online:
May 2009
ISBN:
9780199214211
eISBN:
9780191706660
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199214211.003.0002
Subject:
Biology, Biodiversity / Conservation Biology, Evolutionary Biology / Genetics

This chapter reviews the most common measures of genetic variation used in conservation genetic studies. These include percentage of polymorphic loci, alleles per locus/allelic richness, expected ... More


Osteoporosis

André G. Uitterlinden, Joyce B. J. van Meurs, and Fernando Rivadeneira

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0017
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter discusses gene-disease associations in osteoporosis. Osteoporosis is — together with osteoarthritis — the most common locomotor disease, and its clinical sequela, including fractures, ... More


Genes and Human Psychological Traits

Thomas J. Jr. Bouchard

in The Innate Mind, Volume 3: Foundations and the Future

Published in print:
2008
Published Online:
January 2008
ISBN:
9780195332834
eISBN:
9780199868117
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195332834.003.0005
Subject:
Philosophy, Philosophy of Mind

This chapter shows that genetic variation is an important feature of virtually every human psychological trait and must be taken into account in any comprehensive explanation (theory) of human ... More


Extreme diversity in the major histocompatibility complex

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0012
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

The Major Histocompatibility Complex on chromosome 6 encodes a diverse array of genes involved in the immune and inflammatory response. The region is remarkably polymorphic and has been associated ... More


Agricultural improvement in modern times

Denis J. Murphy

in People, Plants and Genes: The Story of Crops and Humanity

Published in print:
2007
Published Online:
September 2007
ISBN:
9780199207145
eISBN:
9780191708893
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199207145.003.0016
Subject:
Biology, Plant Sciences and Forestry

Modern agriculture has created the world we live in today, most notably by enabling farmers to feed a population of over six billion, possibly rising to ten billion by 2050. Key advances have been ... More


Bladder cancer

Jonine D. Figueroa, Montserrat Garcia-Closas, and Nathaniel Rothman

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0015
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

A literature search was performed using the HuGE Navigator with the term “bladder cancer” and PubMed searches with the terms “ bladder cancer polymorphisms” and “bladder cancer risk variants” through ... More


Evolutionary Processes Explaining the Genetic Variance in Personality: An Exploration of Scenarios

Steven W. Gangestad

in The Evolution of Personality and Individual Differences

Published in print:
2010
Published Online:
May 2011
ISBN:
9780195372090
eISBN:
9780199893485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195372090.003.0012
Subject:
Psychology, Evolutionary Psychology, Social Psychology

This chapter has two major aims. First, to describe the primary scenarios under which genetic variation in phenotypic individual differences is maintained, and illustrate how they have been or could ... More


The role of epidemiology in assessing the potential clinical impact of pharmacogenomics

David L. Veenstra

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0027
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

A promising area of genomics is the use of information about genetic variation to guide drug therapy, a field known as pharmacogenomics. Pharmacogenomic applications can be broadly categorized into ... More


View: