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Living with Embodied Omens

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0008
Subject:
Anthropology, Social and Cultural Anthropology

This chapter begins with a brief consideration of the anthropological literature on divination. This is followed by a condensed discussion composed primarily of ethnographic research findings about ... More


Genetics, Cloning, and Stem Cell Research

Adil E. Shamoo and David B. Resnik

in Responsible Conduct of Research

Published in print:
2009
Published Online:
May 2009
ISBN:
9780195368246
eISBN:
9780199867615
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195368246.003.0014
Subject:
Biology, Disease Ecology / Epidemiology, Biochemistry / Molecular Biology

This chapter provides an overview of ethical, social, and policy issues related to research on human genetics and embryonic stem cells. It covers such topics as genetic engineering of animals and ... More


Rapid, evidence-based reviews of genetic tests

James M. Gudgeon, Glenn E. Palomaki, and Marc S. Williams

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0024
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Genetic and genomic tests are rapidly emerging from the efforts of the Human Genome Project. As of August 2009, GeneTests listed 599 laboratories testing for 1,772 diseases, of which 1,498 are ... More


Evaluation of predictive genetic tests for common diseases: bridging epidemiological, clinical, and public health measures

A. Cecile J. W. Janssens, Marta Gwinn, and Muin J. Khoury

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0022
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter discusses how clinical epidemiologic concepts and methods can be used to assess whether one or more genetic variants (e.g. genome profiles) can be used to predict risk for human ... More


Consumer perspectives on genetic testing: lessons learned

Mary E. Davidson, Karey David, Nancy Hsu, Toni I. Pollin, Joan O. Weiss, Nachama Wilker, and Mary Ann Wilson

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0030
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The Genetic Alliance—a coalition of consumers, professionals, and support groups concerned with the needs of individuals and families living with genetic conditions—works to educate the general ... More


Genetic advances and health insurance

Lilia Filipova and Michael Hoy

in The Economics of New Health Technologies: Incentives, organization, and financing

Published in print:
2009
Published Online:
February 2010
ISBN:
9780199550685
eISBN:
9780191720543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199550685.003.0008
Subject:
Public Health and Epidemiology, Public Health

This chapter addresses the complex issue of the use of genetic advances by health insurance. Technical innovation in medical care in general generates a great deal of interest and controversy. Of ... More


A Rapid-ACCE review of CYP2C9 and VKORC1 allele testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding

Monica R. McClain, Glenn E. Palomaki, Margaret Piper, and James E. Haddow

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0031
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter describes the results from a Rapid-ACCE review (Analytic validity, Clinical validity, Clinical utility, and Ethical, legal, and social implications), designed to facilitate the ... More


Medical and public health strategies for ensuring the quality of genetic testing

Michael S. Watson

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0012
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Over the past ten to fifteen years, significant changes have made medical genetics among the most exciting and rapidly evolving areas of medicine. This chapter discusses the issues facing this field, ... More


Consent to genetic testing: a family affair?

Nina Hallowell

in The Limits of Consent: A socio-ethical approach to human subject research in medicine

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231461
eISBN:
9780191723858
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231461.003.0011
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter explores the extent to which the familial nature of genetic information creates an ethical problem for our current conceptions of informed consent in the context of genetic testing. ... More


Genetics and public health: A framework for the integration of human genetics into public health practice

Muin J. Khoury, Wylie Burke, and Elizabeth J. Thomson

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter begins with a discussion of the need for public health leadership in genetics and the emergence of a new hybrid subspecialty of genetics and public health. It then presents a framework ... More


Orientations

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0001
Subject:
Anthropology, Social and Cultural Anthropology

This introductory chapter discusses the generation and transformation of expert knowledge and practices in connection with the phenomenon of Alzheimer disease (AD) in an era of increasing ... More


Bioethics and Law in Action—Mining the Gaps: The Human Genome Research Project

Mark Henaghan

in Law and Bioethics: Current Legal Issues Volume 11

Published in print:
2008
Published Online:
January 2009
ISBN:
9780199545520
eISBN:
9780191721113
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199545520.003.0013
Subject:
Law, Medical Law

A gap exists between stating ethical principles and choosing which one to apply in a particular situation. Even when the choice of ethical principle is made, there is a gap between the expression of ... More


Computing Evidence

Christa Teston

in Bodies in Flux: Scientific Methods for Negotiating Medical Uncertainty

Published in print:
2017
Published Online:
September 2017
ISBN:
9780226450520
eISBN:
9780226450834
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226450834.003.0005
Subject:
History, History of Science, Technology, and Medicine

Genetic tests help us negotiate the uncertainty posed by a body’s inherited genetic legacy. In the United States, it has never before been more affordable and available. On what behind-the-scenes ... More


Genetics and prevention effectiveness

Scott D. Grosse and Steven M. Teutsch

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0018
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter is intended to help the reader critically evaluate quantitative prevention-effectiveness studies in genetics and to understand their uses and limitations. No prior knowledge of ... More


“Your Genetic Information Should Be Controlled by You”: Personalized Genetic Testing

Donna Dickenson

in Me Medicine vs. We Medicine: Reclaiming Biotechnology for the Common Good

Published in print:
2016
Published Online:
November 2015
ISBN:
9780231159753
eISBN:
9780231534413
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231159753.003.0002
Subject:
Public Health and Epidemiology, Public Health

This chapter discusses how consumerized genetic testing has become controversial, since it both involves a direct relationship between consumer, researcher, and industry, and because it is grounded ... More


Genetic Ancestry Tests and Race: Who Takes Them, Why, and How Do They Affect Racial Identities?

Wendy D. Roth and Katherine A. Lyon

in Reconsidering Race: Social Science Perspectives on Racial Categories in the Age of Genomics

Published in print:
2018
Published Online:
May 2018
ISBN:
9780190465285
eISBN:
9780190465315
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190465285.003.0008
Subject:
Political Science, Political Theory, Comparative Politics

This chapter probes genetic ancestry tests, which are being used increasingly by individuals for a number of reasons. Many are seeking ways to fill in gaps in their family tree; some are hoping to ... More


Genomic Information and Suffering in the Genomic Era

Roberta M. Berry

in Suffering and Bioethics

Published in print:
2014
Published Online:
November 2014
ISBN:
9780199926176
eISBN:
9780199396788
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199926176.003.0019
Subject:
Philosophy, Moral Philosophy, Philosophy of Religion

Genomic information and its applications promise to relieve suffering. However, the operation of the genomic enterprise may impose “iatrogenic suffering” by failures of first-generation cures and by ... More


The Value of Pharmacogenomic Information

John A. Graves, Zilu Zhou, Shawn Garbett, and Josh F. Peterson

in Economic Dimensions of Personalized and Precision Medicine

Published in print:
2019
Published Online:
September 2019
ISBN:
9780226611068
eISBN:
9780226611235
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226611235.003.0004
Subject:
Economics and Finance, Microeconomics

Pharmacogenomics, or the application of genetic testing to guide drug selection and/or dosing, is often cited as integral to the vision of how precision medicine can be integrated into routine ... More


Making screening policy

Angela E. Raffle and J. A. Muir Gray

in Screening: Evidence and practice

Published in print:
2007
Published Online:
September 2009
ISBN:
9780199214495
eISBN:
9780191723742
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199214495.003.0008
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter shows how resources, values, beliefs, and commercial factors all influence screening policy, and gives clear insight into some of the ethical dilemmas involved. Case histories include ... More


Of Dogs, Daycare, and Discipline: A “Genetic Guide to Parenting”?

James Tabery

in Beyond Versus: The Struggle to Understand the Interaction of Nature and Nurture

Published in print:
2014
Published Online:
January 2015
ISBN:
9780262027373
eISBN:
9780262324144
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262027373.003.0008
Subject:
History, History of Science, Technology, and Medicine

Depending on which gene a child has, being sent to daycare can either increase or decrease a child’s chances of developing allergies. Likewise, children with one form of a gene respond better to an ... More


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