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Fallible Design: Protein-Coding DNA Sequences

John C. Avise

in Inside the Human Genome: A Case for Non-Intelligent Design

Published in print:
2010
Published Online:
May 2010
ISBN:
9780195393439
eISBN:
9780199775415
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393439.003.0002
Subject:
Biology, Evolutionary Biology / Genetics

This chapter addresses the history and current state of knowledge about human inborn errors of metabolism. Mutations in protein‐coding genes slaughter or maim countless individuals (especially ... More


Population Growth, Genetic Load, and the Limits of Selection

John O. Reiss

in Not by Design: Retiring Darwin's Watchmaker

Published in print:
2009
Published Online:
March 2012
ISBN:
9780520258938
eISBN:
9780520944404
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520258938.003.0008
Subject:
Biology, Evolutionary Biology / Genetics

This chapter considers another aspect of the relation between absolute and relative fitness: the relation of overall population growth rate to the variance in relative rate of increase in a ... More


Not by Design: Retiring Darwin's Watchmaker

John Reiss

Published in print:
2009
Published Online:
March 2012
ISBN:
9780520258938
eISBN:
9780520944404
Item type:
book
Publisher:
University of California Press
DOI:
10.1525/california/9780520258938.001.0001
Subject:
Biology, Evolutionary Biology / Genetics

More than two centuries ago, William Paley introduced his famous metaphor of the universe as a watch made by the Creator. For him, the exquisite structure of the universe necessitated a designer. ... More


Existence and the Mathematics of Selection: The Adaptive Landscape versus the Fundamental Theorem

John O. Reiss

in Not by Design: Retiring Darwin's Watchmaker

Published in print:
2009
Published Online:
March 2012
ISBN:
9780520258938
eISBN:
9780520944404
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520258938.003.0007
Subject:
Biology, Evolutionary Biology / Genetics

Darwin's separation between adaptedness and existence entered into modern evolutionary theory at its root, in the population genetics work of Sewall Wright and J. B. S. Haldane. This chapter shows ... More


The Origin of Translation and the Genetic Code

John Maynard Smith and Eors Szathmary

in The Major Transitions in Evolution

Published in print:
1997
Published Online:
November 2020
ISBN:
9780198502944
eISBN:
9780191919237
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198502944.003.0010
Subject:
Earth Sciences and Geography, Palaeontology: Earth Sciences

The origin of the code is perhaps the most perplexing problem in evolutionary biology. The existing translational machinery is at the same time so complex, so universal, and so essential that it is ... More


Pointing the Way to Additional Topics

Áki J. Láruson and Floyd A. Reed

in Population Genetics with R: An Introduction for Life Scientists

Published in print:
2021
Published Online:
March 2021
ISBN:
9780198829539
eISBN:
9780191868092
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198829539.003.0009
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies, Evolutionary Biology / Genetics

This concluding chapter highlights many of the concepts that are important to understanding modern-day population genetics research and explains that while they may not have been covered in this ... More


The theory of natural selection

Glenn-Peter Sætre and Mark Ravinet

in Evolutionary Genetics: Concepts, Analysis, and Practice

Published in print:
2019
Published Online:
July 2019
ISBN:
9780198830917
eISBN:
9780191868993
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830917.003.0004
Subject:
Biology, Evolutionary Biology / Genetics, Biomathematics / Statistics and Data Analysis / Complexity Studies

Natural selection is the scientific explanation for the evolution of adaptations. Wonders of the living world, such as the anatomy and physiology that grants the cheetah its unchallenged running ... More


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