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Genetic Linkage Studies

Ezra Susser, Sharon Schwartz, Alfredo Morabia, and Evelyn J. Bromet

in Psychiatric Epidemiology: Searching for the Causes of Mental Disorders

Published in print:
2006
Published Online:
September 2009
ISBN:
9780195101812
eISBN:
9780199864096
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195101812.003.32
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter describes the basic concepts and methods of genetic linkage studies. It first describes what linkage means and how investigators go about detecting linkage. It then discusses the causal ... More


Theoretical underpinning for the use of sibling studies in life course epidemiology

Kate W Strully and Gita D Mishra

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0003
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Siblings can have a great deal in common (e.g., parents, genes, early life home env1ironments, etc.), but they are also distinct individuals with unique personalities and physical traits. This ... More


Mitonuclear mate choice

Geoffrey E. Hill

in Mitonuclear Ecology

Published in print:
2019
Published Online:
June 2019
ISBN:
9780198818250
eISBN:
9780191859465
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198818250.003.0008
Subject:
Biology, Ecology, Evolutionary Biology / Genetics

At each new generation, sexual reproduction creates new combinations of nuclear and mitochondrial genes, and the potential arises for mitonuclear incompatibilities and reduced fitness. Sexual ... More


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