Joanne Lee, Wendy K. Tam Cho, and George Judge
- Published in print:
- 2015
- Published Online:
- October 2017
- ISBN:
- 9780691147611
- eISBN:
- 9781400866595
- Item type:
- chapter
- Publisher:
- Princeton University Press
- DOI:
- 10.23943/princeton/9780691147611.003.0017
- Subject:
- Mathematics, Probability / Statistics
This chapter examines and searches for evidence of fraud in two clinical data sets from a highly publicized case of scientific misconduct. In this case, data were falsified by Eric Poehlman, a ...
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This chapter examines and searches for evidence of fraud in two clinical data sets from a highly publicized case of scientific misconduct. In this case, data were falsified by Eric Poehlman, a faculty member at the University of Vermont, who pleaded guilty to fabricating more than a decade of data, some connected to federal grants from the National Institutes of Health. Poehlman had authored influential studies on many topics; including obesity, menopause, lipids, and aging. The chapter's classical Benford analysis along with a presentation of a more general class of Benford-like distributions highlights interesting insights into this and similar cases. In addition, this chapter demonstrates how information-theoretic methods and other data-adaptive methods are promising tools for generating benchmark distributions of first significant digits (FSDs) and examining data sets for departures from expectations.Less
This chapter examines and searches for evidence of fraud in two clinical data sets from a highly publicized case of scientific misconduct. In this case, data were falsified by Eric Poehlman, a faculty member at the University of Vermont, who pleaded guilty to fabricating more than a decade of data, some connected to federal grants from the National Institutes of Health. Poehlman had authored influential studies on many topics; including obesity, menopause, lipids, and aging. The chapter's classical Benford analysis along with a presentation of a more general class of Benford-like distributions highlights interesting insights into this and similar cases. In addition, this chapter demonstrates how information-theoretic methods and other data-adaptive methods are promising tools for generating benchmark distributions of first significant digits (FSDs) and examining data sets for departures from expectations.