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Using Magnetoencephalography to Elucidate the Principles of Deep Brain Stimulation

Morten L. Kringelbach, Peter C. Hansen, Alex L. Green, and Tipu Z. Aziz

in MEG: An Introduction to Methods

Published in print:
2010
Published Online:
September 2010
ISBN:
9780195307238
eISBN:
9780199863990
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195307238.003.0015
Subject:
Neuroscience, Behavioral Neuroscience, Techniques

Deep brain stimulation (DBS) is a powerful clinical tool that has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders. The precise mechanisms ... More


Electrical stimulation of deep brain structures and speech

Elina Tripoliti and Patricia Limousin

in Speech Motor Control: New developments in basic and applied research

Published in print:
2010
Published Online:
March 2012
ISBN:
9780199235797
eISBN:
9780191696671
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235797.003.0018
Subject:
Neuroscience, Sensory and Motor Systems

This chapter describes the effects of deep brain stimulation on speech in Parkinson's disease (PD). The process involves the implantation of two electrodes either in the ventro-intermediate nucleus ... More


Diseases of the nervous system

Fabrizio Benedetti

in Placebo Effects: Understanding the mechanisms in health and disease

Published in print:
2008
Published Online:
September 2009
ISBN:
9780199559121
eISBN:
9780191724022
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199559121.003.0004
Subject:
Neuroscience, Molecular and Cellular Systems

Besides pain, Parkinson's disease represents an excellent model to study the neurobiological mechanisms of the placebo effect. The placebo effect in Parkinson's disease is mediated by dopamine ... More


Stimulating Brains, Altering Minds

Walter Glannon

in Brain, Body, and Mind: Neuroethics with a Human Face

Published in print:
2011
Published Online:
May 2011
ISBN:
9780199734092
eISBN:
9780199894475
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199734092.003.0016
Subject:
Philosophy, Moral Philosophy

This chapter considers the use of deep-brain stimulation as a treatment for neurological and psychiatric disorders. It addresses the question of whether a person with a disease of the mind can ... More


Brain and Behavior Deficits in De Novo Parkinson Disease

David E. Vaillancourt and Janey Prodoehl

in Motor Control: Theories, Experiments, and Applications

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195395273
eISBN:
9780199863518
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195395273.003.0015
Subject:
Neuroscience, Sensory and Motor Systems

Over the past several decades, models of basal ganglia function that describe the pathophysiology of Parkinson disease (PD) have emerged from studies in both nonhuman primates and rodents. One ... More


Effects of Surgical Treatment

Anna L. Bartels and Klaus L. Leenders

in Imaging in Parkinson’s Disease

Published in print:
2011
Published Online:
September 2011
ISBN:
9780195393484
eISBN:
9780199914494
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393484.003.0109
Subject:
Neuroscience, Disorders of the Nervous System, Techniques

This chapter summarizes the contribution of imaging to the current understanding of the mechanisms underlying surgical interventions for PD. Structural imaging studies using MRI techniques have ... More


Parkinsonian Tremor

Ioannis U. Isaias and Angelo Antonini

in Imaging in Parkinson’s Disease

Published in print:
2011
Published Online:
September 2011
ISBN:
9780195393484
eISBN:
9780199914494
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393484.003.0046
Subject:
Neuroscience, Disorders of the Nervous System, Techniques

Parkinson’s disease (PD) tremor has been found to be a variable clinical feature of the disease both across patients and within individual patients over the disease course. Clinical ratings of tremor ... More


Microelectrode Recordings in Deep Brain Stimulation Surgery

Itzhak Fried

in Single Neuron Studies of the Human Brain: Probing Cognition

Published in print:
2014
Published Online:
January 2015
ISBN:
9780262027205
eISBN:
9780262323994
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262027205.003.0015
Subject:
Neuroscience, Research and Theory

This chapter summarizes techniques used for the placement of deep brain stimulation (DBS) electrodes. These procedures are performed primarily for the treatment of movement disorders such as ... More


Brain, Body, and Mind: Neuroethics with a Human Face

Walter Glannon

Published in print:
2011
Published Online:
May 2011
ISBN:
9780199734092
eISBN:
9780199894475
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199734092.001.0001
Subject:
Philosophy, Moral Philosophy

This book is a discussion of the most timely and contentious issues in the two branches of neuroethics: the neuroscience of ethics; and the ethics of neuroscience. Drawing upon recent work in ... More


Ethical challenges of modern psychiatric neurosurgery

Sabine Müller

in Neuroethics: Anticipating the future

Published in print:
2017
Published Online:
September 2017
ISBN:
9780198786832
eISBN:
9780191839894
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198786832.003.0013
Subject:
Neuroscience, Techniques

Psychiatric neurosurgery is defined as neurosurgery for treating psychiatric disorders that do not have identified structural brain anomalies. Early psychiatric neurosurgery procedures such as ... More


Management of tinnitus

Jos J. Eggermont

in The Neuroscience of Tinnitus

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199605606
eISBN:
9780191741555
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199605606.003.0012
Subject:
Neuroscience, Sensory and Motor Systems, Development

It is clear that management of tinnitus requires alterations of neural activity in the CNS. The neural substrates of tinnitus suggest various approaches to modify neural processing and change the ... More


The use of brain stimulation technology for cognitive enhancement and the potential for addiction

Mark Attiah

in Rethinking Cognitive Enhancement

Published in print:
2017
Published Online:
April 2017
ISBN:
9780198727392
eISBN:
9780191835230
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198727392.003.0009
Subject:
Psychology, Psychopharmacology, Cognitive Neuroscience

The phrase “brain stimulation” conjures a vast range of emotions from different segments of society, with fear or apprehension being a common and understandable reaction. The brain reigns as the ... More


Diseases of the nervous system

Benedetti Fabrizio

in Placebo Effects: 2nd Edition: Understanding the mechanisms in health and disease

Published in print:
2014
Published Online:
October 2014
ISBN:
9780198705086
eISBN:
9780191789151
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198705086.003.0005
Subject:
Neuroscience, Behavioral Neuroscience, Molecular and Cellular Systems

Besides pain, Parkinson’s disease represents an excellent model to study the neurobiological mechanisms of the placebo effect. The placebo effect in Parkinson’s disease is mediated by dopamine ... More


Primary Topic Article: Neural Repair as a Case Study in Neuroethics *

D. Gareth Jones

in The Future of Bioethics: International Dialogues

Published in print:
2014
Published Online:
January 2014
ISBN:
9780199682676
eISBN:
9780191763168
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199682676.003.0006
Subject:
Philosophy, Moral Philosophy

Neuroethics traditionally pays little attention to neural degeneration and regeneration, areas central to much of current neuroscience. Underlying these interests is the ongoing plasticity of the ... More


Understanding the Neurobiology of Core Positive Emotions through Animal Models: Affective and Clinical Implications

Jaak Panksepp

in Positive Emotion: Integrating the Light Sides and Dark Sides

Published in print:
2014
Published Online:
April 2014
ISBN:
9780199926725
eISBN:
9780199394531
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199926725.003.0008
Subject:
Psychology, Social Psychology

This chapter summarizes the primary-process (“core”) positive emotions that are the birthrights of mammals and the foundations of the human mind, and which are next to impossible to understand ... More


Informed Consent for Next-Generation Deep Brain Stimulation Psychiatric Research: Engaging End Users to Understand Risks and Improve Practice

Eran Klein

in Research Involving Participants with Cognitive Disability and Difference: Ethics, Autonomy, Inclusion, and Innovation

Published in print:
2019
Published Online:
October 2019
ISBN:
9780198824343
eISBN:
9780191863165
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198824343.003.0013
Subject:
Neuroscience, Behavioral Neuroscience, Techniques

Deep brain stimulation (DBS) for psychiatric illness raises challenges for informed consent. Some of these are well recognized, such as vulnerability and unrealistic expectations, problems with ... More


Regulating Cognitive Enhancement Technologies: Policy Options and Problems

Robert H. Blank

in Cognitive Enhancement: Ethical and Policy Implications in International Perspectives

Published in print:
2016
Published Online:
August 2016
ISBN:
9780199396818
eISBN:
9780199396825
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199396818.003.0015
Subject:
Philosophy, General, Moral Philosophy

The chapter first describes the policy options that are available to policy makers to regulate research, marketing, and individual use of cognitive enhancement technologies. It then examines the ... More


Are Patients with Psychiatric Disorders “Uniquely” Vulnerable in the Context of DBS Research?: Commentary on Klein (Chapter 13)

Laura B. Dunn and Paul E. Holtzheimer

in Research Involving Participants with Cognitive Disability and Difference: Ethics, Autonomy, Inclusion, and Innovation

Published in print:
2019
Published Online:
October 2019
ISBN:
9780198824343
eISBN:
9780191863165
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198824343.003.0018
Subject:
Neuroscience, Behavioral Neuroscience, Techniques

As investigators look to “next-generation” deep brain stimulation (DBS) approaches, renewed enthusiasm is emerging for DBS for psychiatric disorders. This commentary on Chapter 13 (“Informed Consent ... More


Containing Violence and Controlling Desire

John McMillan

in Treatment for Crime: Philosophical Essays on Neurointerventions in Criminal Justice

Published in print:
2018
Published Online:
November 2018
ISBN:
9780198758617
eISBN:
9780191818530
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198758617.003.0013
Subject:
Philosophy, Moral Philosophy

Deep brain stimulation and wireless deep brain stimulation have the potential to reduce or control violent dispositions. This raises the question of whether enhancing the morality of those who are ... More


Obsessive-Compulsive Disorder

Vladan Starcevic, MD, PhD

in Anxiety Disorders in Adults: A Clinical Guide

Published in print:
2009
Published Online:
November 2020
ISBN:
9780195369250
eISBN:
9780197562642
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195369250.003.0010
Subject:
Clinical Medicine and Allied Health, Psychiatry

As its name implies, the main characteristics of obsessive-compulsive disorder (OCD) are obsessions and/or compulsions. Different types of obsessions and compulsions make OCD a heterogeneous ... More


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