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HREM IN BIOLOGY, ORGANIC CRYSTALS, AND RADIATION DAMAGE

JOHN C. H. SPENCE

in High-Resolution Electron Microscopy

Published in print:
2008
Published Online:
January 2010
ISBN:
9780199552757
eISBN:
9780191708664
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199552757.003.0006
Subject:
Physics, Atomic, Laser, and Optical Physics

This chapter discusses the relationship between ‘absorption’ and phase contrast for biological imaging. It then discusses the theory for imaging single atoms, with full detail of an experimental ... More


Imaging molecules: radiation damage

John C. H. Spence

in High-Resolution Electron Microscopy

Published in print:
2013
Published Online:
January 2014
ISBN:
9780199668632
eISBN:
9780191749322
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199668632.003.0006
Subject:
Physics, Condensed Matter Physics / Materials

Chapter 6 is devoted to the imaging of radiation-sensitive materials, such as organic material, at high resolution using electron microscopy. The methods of single-particle imaging in cryo-electron ... More


High-Resolution Electron Microscopy

John C. H. Spence

Published in print:
2013
Published Online:
January 2014
ISBN:
9780199668632
eISBN:
9780191749322
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199668632.001.0001
Subject:
Physics, Condensed Matter Physics / Materials

High-resolution electron microscopy covers both the practice and theory of atomic-resolution transmission electron microscopy (TEM) in all its modern forms and applications, with the aim of ‘seeing ... More


Introduction

Joachim Frank

in Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State

Published in print:
2006
Published Online:
April 2010
ISBN:
9780195182187
eISBN:
9780199893416
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195182187.003.0001
Subject:
Biology, Biochemistry / Molecular Biology

This introductory chapter begins with an appreciation of the unique position of electron microscopy in biological research as it bridges a wide gap between X-ray crystallography and light microscopy. ... More


The Summing Up: The Astonishing Successes of the LMB and the Dawn of a New Structural Biological Era

John Meurig Thomas

in Architects of Structural Biology: Bragg, Perutz, Kendrew, Hodgkin

Published in print:
2020
Published Online:
March 2020
ISBN:
9780198854500
eISBN:
9780191888793
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198854500.003.0010
Subject:
Physics, Crystallography: Physics, Soft Matter / Biological Physics

The contrast between the related pre-World War II attitudes to scientific research and those of the current era are described and how this affects modern research. There follows a summary of the ... More


Active Matter

Mathias Grote

in Membranes to Molecular Machines: Active Matter and the Remaking of Life

Published in print:
2019
Published Online:
January 2020
ISBN:
9780226625157
eISBN:
9780226625294
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226625294.003.0003
Subject:
History, History of Science, Technology, and Medicine

This chapter comprises a detailed case history on the emergence of what was to become a model of a molecular “pump,” the photoactive protein bacteriorhodopsin. The surge of research on this brand-new ... More


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