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Surveillance for birth defects and genetic diseases

Lorenzo D. Botto and Pierpaolo Mastroiacovo

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0007
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter describes some surveillance issues that will likely be increasingly relevant as birth-defects surveillance moves into the future, and that provide instructive similarities and contrast ... More


Public Health Surveillance for Chronic Diseases, Injuries, and Birth Defects

Ali H. Mokdad, Joseph L. Annest, Robin M. Ikeda, and Cara T. Mai

in Principles & Practice of Public Health Surveillance

Published in print:
2010
Published Online:
September 2010
ISBN:
9780195372922
eISBN:
9780199866090
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195372922.003.0012
Subject:
Public Health and Epidemiology, Public Health

This chapter describes the application of specific principles to the practice of surveillance of noninfectious diseases and events, specifically chronic diseases, injuries, and birth defects. It ... More


Measurement of Trend (a 2 by c Table)

Steve Selvin

in Epidemiologic Analysis: A Case-Oriented Approach

Published in print:
2001
Published Online:
September 2009
ISBN:
9780195146189
eISBN:
9780199864720
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195146189.003.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter compares the frequency of infants with a single congenital malformation to that of infants with multiple congenital malformations, focusing on evaluating changes over time. Extensive ... More


Delivery of genetic services in developing countries

Victor B. Penchaszadeh

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0017
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter discusses the priorities and organization of genetic services in the developing world against the background of the realities of underdevelopment. To define goals for genetic services in ... More


Nutritional Aspects of Birth Defects

Howard M. Saal

in Pediatric and Adult Nutrition in Chronic Diseases, Developmental Disabilities, and Hereditary Metabolic Disorders: Prevention, Assessment, and Treatment

Published in print:
2017
Published Online:
April 2017
ISBN:
9780199398911
eISBN:
9780199398942
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199398911.003.0060
Subject:
Public Health and Epidemiology, Public Health

This chapter discusses nutritional aspects of birth defects, including physical, biochemical, and other abnormalities; nutritional factors (specifically of neural tube defects); and nutritional ... More


Matched Analysis (One Case and Two Controls)

Steve Selvin

in Epidemiologic Analysis: A Case-Oriented Approach

Published in print:
2001
Published Online:
September 2009
ISBN:
9780195146189
eISBN:
9780199864720
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195146189.003.0008
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter examined whether exposure to electromagnetic radiation is associated with the risk of a birth defect. More specifically, does a newborn infant whose mother lives near high-voltage power ... More


Log-Linear Model (Poisson Model Applied to Tabular Data)

Steve Selvin

in Epidemiologic Analysis: A Case-Oriented Approach

Published in print:
2001
Published Online:
September 2009
ISBN:
9780195146189
eISBN:
9780199864720
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195146189.003.0012
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter examines the influence of vitamin use on the risk of a neural tube birth defect while accounting for possible differences associated with race/ethnicity. Using a loglinear model, the ... More


Alcohol and pregnancy: fetal alcohol spectrum disorders and the fetal alcohol syndrome

Kenneth R. Warren and Margaret M. Murray

in Alcohol: Science, Policy and Public Health

Published in print:
2013
Published Online:
May 2013
ISBN:
9780199655786
eISBN:
9780191757082
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199655786.003.0038
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Today, alcohol is recognized as one of the leading preventable causes of birth defects and developmental disorders. It is now established that there are a range of effects on the developing foetus ... More


A binary variable—twin pairs

Steve Selvin

in The Joy of Statistics: A Treasury of Elementary Statistical Tools and their Applications

Published in print:
2019
Published Online:
May 2019
ISBN:
9780198833444
eISBN:
9780191872280
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198833444.003.0038
Subject:
Mathematics, Probability / Statistics, Applied Mathematics

Binary data is often an important type of data. The description of twin pairs presents an extensive example. Also introduced are the statistical consequences of random pairs illustrated by the ... More


Nutritional Epidemiology

Walter Willett

Published in print:
2012
Published Online:
January 2013
ISBN:
9780199754038
eISBN:
9780199979448
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199754038.001.0001
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

This book is about the complex relationships between diet and risks of important diseases, such as cancer and cardiovascular disease. The book starts with an overview of research strategies in ... More


Reproductive and Developmental Disorders

Linda M. Frazier and Deborah Barkin Fromer

in Occupational and Environmental Health

Published in print:
2017
Published Online:
November 2017
ISBN:
9780190662677
eISBN:
9780190662707
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190662677.003.0027
Subject:
Public Health and Epidemiology, Public Health

This chapter describes reproductive disorders and developmental disorders, with a focus on their recognition and prevention. Certain hazardous exposures at sufficient doses during preconception among ... More


Living with Spina Bifida: A Guide for Families and Professionals

Adrian Sandler, M.D.

Published in print:
2004
Published Online:
July 2014
ISBN:
9780807855478
eISBN:
9781469604626
Item type:
book
Publisher:
University of North Carolina Press
DOI:
10.5149/9780807867860_sandler
Subject:
History, Social History

It is the most common complex birth defect. Spina bifida affects approximately one out of every 1,000 children born in the United States. This comprehensive guide offers a wealth of useful ... More


Lessons learned from newborn screening for phenylketonuria

Kenneth A. Pass

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0020
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter discusses the lessons learned from newborn screening for phenylketonuria (PKU) in the U.S. Newborn screening is, conceptually, a simple public health program with well-defined goals. The ... More


Specialized registers

A. Ahlbom and N. Hammar

in Geographical and Environmental Epidemiology: Methods for Small Area Studies

Published in print:
1996
Published Online:
September 2009
ISBN:
9780192622358
eISBN:
9780191723636
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192622358.003.0008
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

All epidemiological investigations require information on the number of cases of the health event under study and on the population and time period that generated the cases. In any country, data on ... More


The obstetric outcome of pregnant women with psychotic disorders

Louise M. Howard

in Title Pages

Published in print:
2014
Published Online:
November 2020
ISBN:
9780199676859
eISBN:
9780191918346
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199676859.003.0005
Subject:
Clinical Medicine and Allied Health, Psychiatry

In 1996, when I was working with Channi as a psychiatry trainee, we were both struck by how often we were seeing women with psychotic disorders in the outpatient clinic who were seeking advice on ... More


Outbreak Detection: Application to Infectious Disease Surveillance

Paddy Farrington and Nick Andrews

in Monitoring the Health of Populations: Statistical Principles and Methods for Public Health Surveillance

Published in print:
2003
Published Online:
September 2009
ISBN:
9780195146493
eISBN:
9780199864928
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195146493.003.0008
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter describes the methodological issues involved in outbreak detection and gives examples from a range of statistical techniques. It focuses on infectious disease detection because most ... More


A Holistic Overview of Spina Bifida

Adrian Sandler

in Living with Spina Bifida: A Guide for Families and Professionals

Published in print:
2004
Published Online:
July 2014
ISBN:
9780807855478
eISBN:
9781469604626
Item type:
chapter
Publisher:
University of North Carolina Press
DOI:
10.5149/9780807867860_sandler.6
Subject:
History, Social History

This chapter begins with a clinical description of “spina bifida.” Literally, spina bifida means a split or divided spine. It is a birth defect that occurs within the first month of pregnancy, when ... More


Children’s Environmental Health

Philip J. Landrigan

in Occupational and Environmental Health

Published in print:
2017
Published Online:
November 2017
ISBN:
9780190662677
eISBN:
9780190662707
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190662677.003.0033
Subject:
Public Health and Epidemiology, Public Health

Children are exquisitely vulnerable to health threats in the environment. The World Health Organization estimates that 36% of all deaths in children worldwide are caused by harmful environmental ... More


Flexible Bayesian modelling for clustered categorical responses in developmental toxicology

Kottas Athanasios and Fronczyk Kassandra

in Bayesian Theory and Applications

Published in print:
2013
Published Online:
May 2013
ISBN:
9780199695607
eISBN:
9780191744167
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199695607.003.0005
Subject:
Mathematics, Probability / Statistics

Developmental toxicity studies investigate birth defects caused by toxic chemicals. This chapter develops a Bayesian nonparametric modelling approach for risk assessment in developmental toxicity ... More


Growing Protest at Love Canal

Richard S. Newman

in Love Canal: A Toxic History from Colonial Times to the Present

Published in print:
2016
Published Online:
November 2020
ISBN:
9780195374834
eISBN:
9780197562673
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195374834.003.0014
Subject:
Environmental Science, Pollution and Threats to the Environment

As the seasons turned and a new year passed, Love Canal remained a whirlwind of remediation activity. “A plan is being set in motion now to implement technical procedures designed to meet the ... More


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