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Ancestral Sequence Reconstruction

David A Liberles (ed.)

Published in print:
2007
Published Online:
September 2008
ISBN:
9780199299188
eISBN:
9780191714979
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199299188.001.0001
Subject:
Biology, Evolutionary Biology / Genetics

Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological ... More


Biostatistics: the near future

Scott Zeger, Peter Diggle, and Kung-Yee Liang

in Celebrating Statistics: Papers in honour of Sir David Cox on his 80th birthday

Published in print:
2005
Published Online:
September 2007
ISBN:
9780198566540
eISBN:
9780191718038
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566540.003.0009
Subject:
Mathematics, Probability / Statistics

This chapter reviews the biomedical and public health developments that will influence biostatistical research and practice in the near future, such as advances in molecular biology, and measuring ... More


Navigating the evolving knowledge of human genetic variation in health and disease

Marta Gwinn and Wei Yu

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0004
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter presents an overview of evolving methods for tracking and compiling information on genetic factors in disease. It discusses bioinformatics, the Human Genome Epidemiology Network ... More


Statistical Theory and Methods for Evolutionary Genomics

Xun Gu

Published in print:
2010
Published Online:
January 2011
ISBN:
9780199213269
eISBN:
9780191594762
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199213269.001.0001
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

Evolutionary genomics is a relatively new research field with the ultimate goal of understanding the underlying evolutionary and genetic mechanisms for the emergence of genome complexity under ... More


Machine Learning in Non-Stationary Environments: Introduction to Covariate Shift Adaptation

Masashi Sugiyama and Motoaki Kawanabe

Published in print:
2012
Published Online:
September 2013
ISBN:
9780262017091
eISBN:
9780262301220
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262017091.001.0001
Subject:
Computer Science, Machine Learning

As the power of computing has grown over the past few decades, the field of machine learning has advanced rapidly in both theory and practice. Machine learning methods are usually based on the ... More


Methods and Technologies for Studying Metals in Biological Systems

Wolfgang Maret, Joseph A. Caruso, Christopher H. Contag, David P. Giedroc, Peter-Leon Hagedoorn, Andreas Matusch, Eric P. Skaar, and Richard B. Thompson

in Trace Metals and Infectious Diseases

Published in print:
2015
Published Online:
May 2016
ISBN:
9780262029193
eISBN:
9780262327619
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029193.003.0020
Subject:
Public Health and Epidemiology, Public Health

An extensive summary is provided on the methods and methodology available to analyze and image total metals in biological systems as well as to assess their speciation, in particular in ... More


Molecular replacement

Dennis Sherwood and Jon Cooper

in Crystals, X-rays and Proteins: Comprehensive Protein Crystallography

Published in print:
2010
Published Online:
January 2011
ISBN:
9780199559046
eISBN:
9780191595028
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199559046.003.0013
Subject:
Physics, Crystallography

This chapter describes a range of methods for solving the phase problem when a structure that is similar to the one being analysed has already been determined. These methods generally rely on ... More


Semi-Supervised Learning

Olivier Chapelle, Bernhard Scholkopf, and Alexander Zien (eds)

Published in print:
2006
Published Online:
August 2013
ISBN:
9780262033589
eISBN:
9780262255899
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262033589.001.0001
Subject:
Computer Science, Machine Learning

In the field of machine learning, semi-supervised learning (SSL) occupies the middle ground, between supervised learning (in which all training examples are labeled) and unsupervised learning (in ... More


The Bioinformatics of integrative medicine in urology

Ernest Lawrence Rossi

in Supportive Care for the Urology Patient

Published in print:
2005
Published Online:
November 2011
ISBN:
9780198529415
eISBN:
9780191730344
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198529415.003.0007
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

The role of integrative approaches to supportive care in urology is as controversial today as at any time in the history of medicine. At present, however, people are witnessing the emergence of a ... More


SAS in multidisciplinary studies

Dmitri I. Svergun, Michel H. J. Koch, Peter A. Timmins, and Roland P. May

in Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules

Published in print:
2013
Published Online:
December 2013
ISBN:
9780199639533
eISBN:
9780191747731
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199639533.003.0010
Subject:
Physics, Crystallography

SAS is most powerful when it integrates results from other techniques such as high-resolution X-ray crystallography, nuclear magnetic resonance, electron microscopy or hydrodynamic studies such as ... More


Building Bioinformatics Solutions

Conrad Bessant, Darren Oakley, and Ian Shadforth

Published in print:
2014
Published Online:
April 2014
ISBN:
9780199658558
eISBN:
9780191779466
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199658558.001.0001
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies, Biochemistry / Molecular Biology

This book provides an introduction to three of the main tools used in the development of bioinformatics software — Perl, R, and MySQL — and explains how these can be used together to tackle the ... More


Using Bioinformatics in Citizen Science

Steve Kelling

in Citizen Science: Public Participation in Environmental Research

Published in print:
2012
Published Online:
August 2016
ISBN:
9780801449116
eISBN:
9780801463952
Item type:
chapter
Publisher:
Cornell University Press
DOI:
10.7591/cornell/9780801449116.003.0004
Subject:
Environmental Science, Environmental Studies

This chapter examines how bioinformatics can be used to advance citizen science engagement opportunities that provide the framework for research, education, and dissemination of information at global ... More


Life Out of Sequence: A Data-Driven History of Bioinformatics

Hallam Stevens

Published in print:
2013
Published Online:
May 2014
ISBN:
9780226080178
eISBN:
9780226080345
Item type:
book
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226080345.001.0001
Subject:
History, History of Science, Technology, and Medicine

During the last thirty years, computers have come to play an increasingly important role in biological work. Especially in the new ‘omic’ disciplines, biologists are as likely to be found in front of ... More


Beyond Belief: The Steady Resurrection of Phenetics

David M. Williams, Malte C. Ebach, and Quentin D. Wheeler

in Beyond Cladistics: The Branching of a Paradigm

Published in print:
2010
Published Online:
March 2012
ISBN:
9780520267725
eISBN:
9780520947993
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520267725.003.0010
Subject:
Biology, Evolutionary Biology / Genetics

In his account of the history of numerical taxonomy, P. H. A. Sneath argued that Hennigian cladistics is a side issue that has not proven its value, and that numerical taxonomy is “the greatest ... More


Introduction

Conrad Bessant, Darren Oakley, and Ian Shadforth

in Building Bioinformatics Solutions

Published in print:
2014
Published Online:
April 2014
ISBN:
9780199658558
eISBN:
9780191779466
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199658558.003.0001
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies, Biochemistry / Molecular Biology

This chapter provides a high level overview of the field of bioinformatics, covering the main areas of interest in contemporary bioinformatics and introducing the pre-eminent software tools and ... More


Through a Glass, Clearly: Experimental Evolution as a Window on Adaptive Genome Evolution

Frank Rosenzweig and Gavin Sherlock

in Experimental Evolution: Concepts, Methods, and Applications of Selection Experiments

Published in print:
2009
Published Online:
March 2012
ISBN:
9780520247666
eISBN:
9780520944473
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520247666.003.0013
Subject:
Biology, Evolutionary Biology / Genetics

This chapter explores recent examples where experimental evolution, empowered by genomic technologies and increasingly informed by systems biology, has fundamentally advanced our understanding of ... More


Biology Meets Computation

Arlindo Oliveira

in The Digital Mind: How Science is Redefining Humanity

Published in print:
2017
Published Online:
September 2017
ISBN:
9780262036030
eISBN:
9780262338394
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262036030.003.0007
Subject:
Computer Science, Artificial Intelligence

This chapter describes how computers played a decisive role in the sequencing and understanding of the genomes of humans and other organisms. The discovery of the structure of DNA, by Watson and ... More


Conservation Challenges in California's Endemic-Rich Landscape

Susan P. Harrison

in Plant and Animal Endemism in California

Published in print:
2013
Published Online:
January 2014
ISBN:
9780520275546
eISBN:
9780520954731
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520275546.003.0006
Subject:
Biology, Ecology

This chapter reviews innovative practices that have originated or been advanced in California for the protection of biological diversity. California has been one of the nation's leaders in initiating ... More


Sentinel Devices: Managing Uncertainty in Species Barrier Zones

Frédéric Keck

in Modes of Uncertainty: Anthropological Cases

Published in print:
2015
Published Online:
January 2016
ISBN:
9780226257075
eISBN:
9780226257242
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226257242.003.0010
Subject:
Anthropology, Anthropology, Global

In the last twenty years, new diseases have emerged when pathogens have crossed species barriers: mad cow disease, avian and swine influenza, Ebola, Nipah, and West Nile viruses. These spillover ... More


Genomics for the 98 Percent?

Jenny Reardon

in The Postgenomic Condition: Ethics, Justice, and Knowledge after the Genome

Published in print:
2017
Published Online:
September 2018
ISBN:
9780226344553
eISBN:
9780226345192
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226345192.003.0006
Subject:
Sociology, Health, Illness, and Medicine

The Human Genome Project’s open-source ethos sat uneasily next to historic commitments to biomedical privacy rights. Google-backed personal genomics (PG) company 23andMe argued that citizens should ... More


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