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Balancing Selection and Disease

Norman A. Johnson

in Darwinian Detectives: Revealing the Natural History of Genes and Genomes

Published in print:
2007
Published Online:
September 2007
ISBN:
9780195306750
eISBN:
9780199790203
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195306750.003.0005
Subject:
Biology, Evolutionary Biology / Genetics

Some forms of selection, called “balancing selection” can maintain variation. Human beta-hemoglobin is an example of a gene under balancing selection. Individuals having two copies of the sickle ... More


Testing the Evolutionary Genetics of Personality: Do Balanced Selection and Gene Flow Cause Genetically Adapted Personality Differences in Human Populations?

Andrea Camperio Ciani

in The Evolution of Personality and Individual Differences

Published in print:
2010
Published Online:
May 2011
ISBN:
9780195372090
eISBN:
9780199893485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195372090.003.0015
Subject:
Psychology, Evolutionary Psychology, Social Psychology

This chapter provides empirical evidence bearing on three competing evolutionary genetic scenarios: neutral selection, mutation selection, and balancing selection. Using an innovative research design ... More


Maintenance of Quantitative Genetic Variation

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0028
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

One of the major unresolved issues in quantitative genetics is what accounts for the amount of standing genetic variation in traits. A wide range of models, all reviewed in this chapter, have been ... More


Natural Selection in Large Populations

Daniel L. Hartl

in A Primer of Population Genetics and Genomics

Published in print:
2020
Published Online:
August 2020
ISBN:
9780198862291
eISBN:
9780191895074
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198862291.003.0005
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies, Evolutionary Biology / Genetics

This chapter includes selection in haploid and diploid organisms, hard and soft selective sweeps, background selection, and the probability of ultimate survival of a new favorable mutation in a large ... More


Natural selection and demography as causes of molecular non-randomness

Asher D. Cutter

in A Primer of Molecular Population Genetics

Published in print:
2019
Published Online:
August 2019
ISBN:
9780198838944
eISBN:
9780191874826
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198838944.003.0007
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

Chapter 7, “Natural selection and demography as causes of molecular non-randomness,” outlines the predictable molecular evolutionary patterns that arise when the Neutral Theory has its assumptions ... More


Individual differences: The unique woman

in A mind of her own: The evolutionary psychology of women

Published in print:
2013
Published Online:
September 2013
ISBN:
9780199609543
eISBN:
9780191747717
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199609543.003.0008
Subject:
Psychology, Evolutionary Psychology, Developmental Psychology

The early aim of evolutionary psychology was to explain human universals. Recently attention has turned to explaining individual differences which present a theoretical challenge. Differences in ... More


The theory of natural selection

Glenn-Peter Sætre and Mark Ravinet

in Evolutionary Genetics: Concepts, Analysis, and Practice

Published in print:
2019
Published Online:
July 2019
ISBN:
9780198830917
eISBN:
9780191868993
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830917.003.0004
Subject:
Biology, Evolutionary Biology / Genetics, Biomathematics / Statistics and Data Analysis / Complexity Studies

Natural selection is the scientific explanation for the evolution of adaptations. Wonders of the living world, such as the anatomy and physiology that grants the cheetah its unchallenged running ... More


Codon models as a vehicle for reconciling population genetics with inter-specific sequence data

Jeffrey L. Thorne, Nicolas Lartillot, Nicolas Rodrigue, and Sang Chul Choi

in Codon Evolution: Mechanisms and Models

Published in print:
2012
Published Online:
May 2015
ISBN:
9780199601165
eISBN:
9780191810114
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:osobl/9780199601165.003.0007
Subject:
Biology, Evolutionary Biology / Genetics

This chapter examines how population genetic inferences can be made from inter-specific data, focusing on the study of inter-specific genetic variation in protein-coding DNA. It begins with a ... More


Offspring Size and Number

Frank J. Messina and Charles W. Fox

in Evolutionary Ecology: Concepts and Case Studies

Published in print:
2001
Published Online:
November 2020
ISBN:
9780195131543
eISBN:
9780197561461
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195131543.003.0014
Subject:
Environmental Science, Applied Ecology

If we look across all organisms, we find that some species produce only one or a few large offspring per reproductive bout (e.g., most birds and mammals), ... More


Evolution theory and the future of humanity

Christopher Wills

in Global Catastrophic Risks

Published in print:
2008
Published Online:
November 2020
ISBN:
9780198570509
eISBN:
9780191918100
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198570509.003.0007
Subject:
Earth Sciences and Geography, Environmental Geography

No field of science has cast more light on both the past and the future of our species than evolutionary biology. Recently, the pace of new discoveries ... More


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