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Hitchhiking and Selective Sweeps

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0008
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

When a favorable allele increases in frequency, it alters the coalescent structure (the pattern of times back to a common ancestor) at linked sites relative to that under drift. This creates patterns ... More


Natural Selection in Large Populations

Daniel L. Hartl

in A Primer of Population Genetics and Genomics

Published in print:
2020
Published Online:
August 2020
ISBN:
9780198862291
eISBN:
9780191895074
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198862291.003.0005
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies, Evolutionary Biology / Genetics

This chapter includes selection in haploid and diploid organisms, hard and soft selective sweeps, background selection, and the probability of ultimate survival of a new favorable mutation in a large ... More


Natural selection and demography as causes of molecular non-randomness

Asher D. Cutter

in A Primer of Molecular Population Genetics

Published in print:
2019
Published Online:
August 2019
ISBN:
9780198838944
eISBN:
9780191874826
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198838944.003.0007
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

Chapter 7, “Natural selection and demography as causes of molecular non-randomness,” outlines the predictable molecular evolutionary patterns that arise when the Neutral Theory has its assumptions ... More


The Genetic Effective Size of a Population

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0003
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

The effects of genetic drift usually assume an idealized population of constant size. This chapter shows how the population size for such an idealized population can be replaced with an effective ... More


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