Angela C. Roberts
- Published in print:
- 2007
- Published Online:
- September 2007
- ISBN:
- 9780195314274
- eISBN:
- 9780199786695
- Item type:
- chapter
- Publisher:
- Oxford University Press
- DOI:
- 10.1093/acprof:oso/9780195314274.003.0016
- Subject:
- Psychology, Cognitive Neuroscience
Dopamine and serotonin have been implicated in a wide variety of cognitive and emotional control processes. This chapter reviews the evidence that these two neuromodulators differentially regulate ...
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Dopamine and serotonin have been implicated in a wide variety of cognitive and emotional control processes. This chapter reviews the evidence that these two neuromodulators differentially regulate two distinct forms of cognitive flexibility in marmoset monkeys, namely, attentional set‐shifting and discrimination reversal learning, through their independent actions within the lateral prefrontal cortex and orbitofrontal cortex, respectively. Consideration is given to the psychological and cellular mechanisms that may underlie their effects, not only at the level of the prefrontal cortex, but also at other neural sites known to contribute to these forms of flexibility, namely, the striatum and amygdala.Less
Dopamine and serotonin have been implicated in a wide variety of cognitive and emotional control processes. This chapter reviews the evidence that these two neuromodulators differentially regulate two distinct forms of cognitive flexibility in marmoset monkeys, namely, attentional set‐shifting and discrimination reversal learning, through their independent actions within the lateral prefrontal cortex and orbitofrontal cortex, respectively. Consideration is given to the psychological and cellular mechanisms that may underlie their effects, not only at the level of the prefrontal cortex, but also at other neural sites known to contribute to these forms of flexibility, namely, the striatum and amygdala.
