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Carpet Monsters

Nicholas P. Money

in Carpet Monsters and Killer Spores: A Natural History of Toxic Mold

Published in print:
2004
Published Online:
September 2007
ISBN:
9780195172270
eISBN:
9780199790258
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195172270.003.0003
Subject:
Biology, Microbiology

This chapter explains how mold spores can cause allergies. Spores carry proteins on their surface, and those that act as antigens can cause a cascade of immune responses resulting in the miseries of ... More


T Cells: The Second Arm of Adapative Immunity

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0004
Subject:
Biology, Disease Ecology / Epidemiology

B cells and antibodies are only one arm of the adaptive immune system, specialized in removing foreign material from blood and lymph. The second arm of the adaptive system consists of T cells, which ... More


Extreme diversity in the major histocompatibility complex

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0012
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

The Major Histocompatibility Complex on chromosome 6 encodes a diverse array of genes involved in the immune and inflammatory response. The region is remarkably polymorphic and has been associated ... More


Interaction of Glial Cells with Monocytes

Ingo Bechmann and Robert Nitsch

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0023
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter begins with a brief overview of the different brain phagocyte populations in regard to the kinetics of their permanent supplementation by blood-derived precursors. It then provides a ... More


Antigen Processing, Presentation, and T Cell Interaction

Harald Neumann

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0024
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter discusses antigen processing, presentation, and T cell interaction. The central nervous system (CNS) is protected by a blood-brain barrier (BBB) designed to minimize the passage of ... More


Immunology, Self and Nonself

Thomas Pradeu and Elizabeth Vitanza

in The Limits of the Self: Immunology and Biological Identity

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199775286
eISBN:
9780199932818
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199775286.003.0002
Subject:
Philosophy, Philosophy of Science, Metaphysics/Epistemology

This chapter investigates the different definitions of immunology, in particular the dominant definition stating that immunology is the discipline that studies the defense of organisms against ... More


The Continuity Theory

Thomas Pradeu and Elizabeth Vitanza

in The Limits of the Self: Immunology and Biological Identity

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199775286
eISBN:
9780199932818
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199775286.003.0005
Subject:
Philosophy, Philosophy of Science, Metaphysics/Epistemology

This chapter offers a new theory in order to explain the triggering of an immune response, called the “continuity theory.” According to this theory, the triggering of an immune response is due to a ... More


Comparing the Continuity Theory to Other Immunological Theories

Thomas Pradeu and Elizabeth Vitanza

in The Limits of the Self: Immunology and Biological Identity

Published in print:
2012
Published Online:
May 2012
ISBN:
9780199775286
eISBN:
9780199932818
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199775286.003.0006
Subject:
Philosophy, Philosophy of Science, Metaphysics/Epistemology

This chapter compares the continuity theory that I propose with the other theories available in today’s immunology, including the self-nonself theory, the systemic theory of the immune “network” ... More


Using Public Health Data to Evaluate Screening Programs: Application to Prostate Cancer

Ruth Etzioni, Larry Kessler, and Dante Dl Tommaso

in Monitoring the Health of Populations: Statistical Principles and Methods for Public Health Surveillance

Published in print:
2003
Published Online:
September 2009
ISBN:
9780195146493
eISBN:
9780199864928
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195146493.003.0006
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter describes the use of computer modeling to quantify the link between prostate-specific antigen (PSA) screening and prostate cancer incidence and mortality. Data resources for both cancer ... More


Information, Decisions, and the Limits of Informed Consent

Carl E. Schneider and Michael H. Farrell

in Law and Medicine: Current Legal Issues Volume 3

Published in print:
2000
Published Online:
March 2012
ISBN:
9780198299189
eISBN:
9780191685644
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198299189.003.0006
Subject:
Law, Philosophy of Law, Medical Law

For many years, the dream of bioethics has been to confide medical decisions to patients and not to doctors. The favoured key to doing so has been the doctrine of informed consent. The success of ... More


A Parasite for All Seasons: Toxoplasma gondii

Dickson D. Despommier and William C. Campbell

in People, Parasites, and Plowshares: Learning From Our Body's Most Terrifying Invaders

Published in print:
2013
Published Online:
November 2015
ISBN:
9780231161947
eISBN:
9780231535267
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231161947.003.0004
Subject:
Public Health and Epidemiology, Public Health

This chapter focuses on the nature of Toxoplasma gondii—an obligate, intracellular, parasitic protozoan that causes the disease toxoplasmosis. This parasite is mostly acquired by eating fecally ... More


Breakthroughs at the Bench

Lara V. Marks

in The Lock and Key of Medicine: Monoclonal Antibodies and the Transformation of Healthcare

Published in print:
2015
Published Online:
January 2016
ISBN:
9780300167733
eISBN:
9780300213522
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300167733.003.0003
Subject:
History, History of Science, Technology, and Medicine

This chapter discusses how monoclonal antibodies (Mabs) opened new frontiers in research well beyond immunology and transformed the way scientists analyzed biological phenomena in the early 1980s. ... More


Joy, Disappointment, Determination: Early Clinical Tests

Lara V. Marks

in The Lock and Key of Medicine: Monoclonal Antibodies and the Transformation of Healthcare

Published in print:
2015
Published Online:
January 2016
ISBN:
9780300167733
eISBN:
9780300213522
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300167733.003.0005
Subject:
History, History of Science, Technology, and Medicine

This chapter considers the development of monoclonal antibodies (Mabs) for cancer treatment. In the early 1980s, many scientists were optimistic that Mabs would defeat cancer. In 1982, John Minna of ... More


Prostate Cancer

Catherine M. Tangen, Marian L. Neuhouser, and Janet L. Stanford

in Cancer Epidemiology and Prevention

Published in print:
2017
Published Online:
December 2017
ISBN:
9780190238667
eISBN:
9780190238698
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190238667.003.0053
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

Prostate cancer is the most common solid tumor and the second leading cause of cancer-related mortality in American men. Worldwide, prostate cancer ranks second and fifth as a cause of cancer and ... More


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